4 research departments
750 employees
45 nationalities
55 research teams
16 ERC laureates
260 publications per year
24000 m² lab area

Support us through

Fondation universite de Strasbourg

Key figures 2019

9 congresses, workshops and meetings
5 special seminars
0 internal seminars
24 thesis


Quick Links


Control of Immunemetabolism by the Glucocorticoid Receptor

Director of the Institute of Comparative Molecular Endocrinology (CME), University of Ulm, Germany

Monday, September 30th 2019 - 11 a.m. - Meeting room 4004, IGBMC
Hosted by Functional genomics and cancer, Daniel METZGER

The glucocorticoid receptor (GR) has pivotal roles in the control of energy metabolism and inflammation. While this was for a long time considered as separated processes, we show now that the GR in macrophages modulate insulin resistance during obesity and that nutrient sensing enzymes mediate GR anti-inflammatory actions in macrophages during acute inflammation and regeneration. 

Thus finetuning of immunometabolism by GR in a cell type specific manner can be beneficial to limit inflammation and reduce insulin resistance. 

Imprimer Envoyer

Université de Strasbourg

IGBMC - CNRS UMR 7104 - Inserm U 1258
1 rue Laurent Fries / BP 10142 / 67404 Illkirch CEDEX / France Tél +33 (0)3 88 65 32 00 / Fax +33 (0)3 88 65 32 01 / directeur.igbmc@igbmc.fr