4 research departments
750 employees
45 nationalities
55 research teams
16 ERC laureates
260 publications per year
24000 m² lab area

Support us through

Fondation universite de Strasbourg



Key figures

52 research teams
127 researchers
34 post-doctoral fellows
31 PhD students
109 engineers & technicians
110 administrators & general services 110 ICS employees

Quick Links

Job opportunities

Postdoctoral Position In Live Imaging Of Chromatin Dynamics

Reference : IGBMC-POD-47

Offer publication : Sept. 23, 2021

Sexton lab, IGBMC, Strasbourg. www.igbmc.fr/sexton
Chromatin architecture has long been linked with regulation of gene expression, in particular via the organization of chromosomes into topologically associated domains and apparent physical proximities between gene promoters and regulatory elements such as enhancers. However, much less is known about how the dynamics of chromatin architectures in real-time. We have recently optimized a system for live imaging of specifically tagged genomic sites and have uncovered surprising locus-specific properties of chromatin diffusive properties (https://www.biorxiv.org/content/10.1101/2021.03.16.435699v1; accepted in Nature Communications). We have also found that enhancer-promoter distance is affected much less than local diffusive properties when comparing transcribing and non-transcribing loci (manuscript in preparation), suggesting that chromatin dynamics may be an important yet largely unexplored facet of gene regulation.


A postdoctoral position is available in the Sexton lab (two years, with possibility to extend) to assess more systematically and mechanistically the link between chromatin dynamics and transcriptional regulation. Expertise in optical microscopy (especially live) and image analysis is highly desirable.

Your application

Please send applications (CV plus cover letter) to sexton@igbmc.fr

Imprimer Envoyer

Université de Strasbourg

IGBMC - CNRS UMR 7104 - Inserm U 1258
1 rue Laurent Fries / BP 10142 / 67404 Illkirch CEDEX / France Tél +33 (0)3 88 65 32 00 / Fax +33 (0)3 88 65 32 01 / directeur.igbmc@igbmc.fr