IGBMC : Institut de la Génétique et de la Biologie Moléculaire et Cellulaire

• Researchers

  Norbert GHYSELINCK

  Manuel MARK

• Post-Doctoral Fellowships

  Aurore GELY PERNOT

• Phd Students

  Mathilde RAVERDEAU

• Engineers & Technicians

  Christine DENNEFELD

  Betty FERET

  Muriel KLOPFENSTEIN

• Master Students

  Mouni STAMBOULI

Development & stems cells

Retinoic acid signaling pathways driving stem spermatogonia ontogenesis and differentiation

Publications

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• Spermatogonia differentiation requires retinoic acid receptor .

  Gely-Pernot A, Raverdeau M, Célébi C, Dennefeld C, Feret B, Klopfenstein M, Yoshida S, Ghyselinck NB, Mark M.

  Endocrinology Jan 2012 ; 153:438-49 .

• Genetic disruption of aurora B uncovers an essential role for aurora C during early mammalian development

  Fernandez-Miranda G., Trakala M., Martin J., Escobar B., Gonzalez A., Ghyselinck N.B., Ortega S., Canamero M., de Castro I.P., Malumbres M.

  Development Jul 2011 ; 138:2661-72 .

• RA-RAR-beta counteracts myelin-dependent inhibition of neurite outgrowth via Lingo-1 repression

  Puttagunta R., Schmandke A., Floriddia E., Gaub P., Fomin N., Ghyselinck N.B., Di Giovanni S.

  J Cell Biol June 27, 2011 ; 193:1147-56 .

• Retinoids enhance glucocorticoid-induced apoptosis of T cells by facilitating glucocorticoid receptor-mediated transcription

  Toth K., Sarang Z., Scholtz B., Brazda P., Ghyselinck N., Chambon P., Fesus L., Szondy Z.

  Cell Death Differ May 2011 ; 18:783-92 .

• Standardized Post-Mortem Examination and Fixation Procedures for Mutant and Treated Mice

  Antal M.C., muller S., Wendling O, Herault Y, Mark M.

  Current Protocols in Mouse Biology 2011 ; 1:1-38 .

• TIF1beta association with HP1 is essential for post-gastrulation development, but not for Sertoli cell functions during spermatogenesis

  Herzog M., Wendling O., Guillou F., Chambon P., Mark M., Losson R., Cammas F.

  Dev Biol Feb. 15, 2011 ; 350:548-58 .

• Transcription cofactors TRIM24, TRIM28, and TRIM33 associate to form regulatory complexes that suppress murine hepatocellular carcinoma

  Herquel B., Ouararhni K., Khetchoumian K., Ignat M., Teletin M., Mark M., Bechade G., Van Dorsselaer A., Sanglier-Cianferani S., Hamiche A., Cammas F., Davidson I., Losson R.

  Proc Natl Acad Sci U S A May 17, 2011 ; 108:8212-7 .

• Retinoic acid drives aryl hydrocarbon receptor expression and is instrumental to dioxin-induced toxicity during palate development.

  Jacobs H, Dennefeld C, Féret B, Viluksela M, Håkansson H, Mark M, Ghyselinck NB.

  Environ Health Perspect Nov 2011 ; 119:1590-5 .