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A continuous evolution system for contracting the host range of bacteriophage T7.
Holtzman T(1)(2), Globus R(1), Molshanski-Mor S(1), Ben-Shem A(3), Yosef I(1), Qimron U(4).
Sci Rep Jan. 15, 2020
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Aminobenzosuberone derivatives as PfA-M1 inhibitors: Molecular recognition and antiplasmodial evaluation.
Salomon E(1), Schmitt M(1), Mouray E(2), McEwen AG(3), Bounaadja L(2), Torchy M(3), Poussin-Courmontagne P(3), Alavi S(1), Tarnus C(1), Cavarelli J(3), Florent I(2), Albrecht S(4).
Bioorg Chem March 11, 2020
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Correlation between equi-partition of aminoacyl-tRNA synthetases and amino-acid biosynthesis pathways.
Takénaka A(1)(2), Moras D(3)(4)(5)(6).
Nucleic Acids Res Jan. 22, 2020
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Including crystallographic symmetry in quantum-based refinement: Q|R#2.
Zheng M(1), Biczysko M(1), Xu Y(1), Moriarty NW(2), Kruse H(3), Urzhumtsev A(4), Waller MP(5), Afonine PV(2).
Acta Crystallogr D Struct Biol Jan. 1, 2020
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In TFIIH the Arch domain of XPD is mechanistically essential for transcription and DNA repair.
Peissert S(1), Sauer F(1), Grabarczyk DB(1), Braun C(2)(3)(4)(5), Sander G(1), Poterszman A(2)(3)(4)(5), Egly JM(6)(7)(8)(9), Kuper J(10), Kisker C(11)(12).
Nat Commun April 3, 2020
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Mechanism of ribosome shutdown by RsfS in Staphylococcus aureus revealed by integrative structural biology approach.
Khusainov I(1)(2)(3), Fatkhullin B(4)(5), Pellegrino S(6)(7), Bikmullin A(4), Liu WT(8), Gabdulkhakov A(5), Shebel AA(4), Golubev A(4)(6), Zeyer D(8), Trachtmann N(4)(9), Sprenger GA(9), Validov S(4), Usachev K(4), Yusupova G(10), Yusupov M(11)(12).
Nat Commun April 3, 2020
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NMR and crystallographic structural studies of the Elongation factor P from Staphylococcus aureus.
Golubev A(1)(2), Fatkhullin B(1)(3), Gabdulkhakov A(3), Bikmullin A(1), Nurullina L(1), Garaeva N(1), Islamov D(1), Klochkova E(1), Klochkov V(4), Aganov A(4), Khusainov I(1)(2)(5), Validov S(1), Yusupova G(2), Yusupov M(1)(2), Usachev K(6)(7).
Eur Biophys J March 9, 2020
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Targeting the Human 80S Ribosome in Cancer: From Structure to Function and Drug Design for Innovative Adjuvant Therapeutic Strategies.
Gilles A(1), Frechin L(2), Natchiar K(2), Biondani G(3), Loeffelholz OV(2), Holvec S(2), Malaval JL(1), Winum JY(1), Klaholz BP(2), Peyron JF(3).
Cells March 5, 2020
