IGBMC : Institut de la Génétique et de la Biologie Moléculaire et Cellulaire

• Researchers

  Nacho MOLINA

• Post-Doctoral Fellows

  Sascha CONIC

  Attila ORAVECZ

  Andrea RIBA

• PhD Students

  Karen AMARAL DE OLIVEIRA

  Guilherme MONTEIRO OLIVEIRA

  Sergio SARNATARO

• Engineers & Technicians

  Olivier TASSY

Development and stem cells

Stochastic Systems Biology of Gene Regulation

Publications

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• Visualization of Endogenous Transcription Factors in Single Cells Using an Antibody Electroporation-Based Imaging Approach.

  Conic S(1)(2)(3)(4), Desplancq D(5)(6), Ferrand A(7), Molina N(8)(9)(10)(5), Weiss E(5)(6), Tora L(11)(12)(13)(14).

  Methods Mol Biol 2019;2038:209-221.

• Co-translational assembly of mammalian nuclear multisubunit complexes.

  Kamenova I(1)(2)(3)(4), Mukherjee P(1)(2)(3)(4), Conic S(1)(2)(3)(4), Mueller F(5), El-Saafin F(1)(2)(3)(4), Bardot P(1)(2)(3)(4), Garnier JM(1)(2)(3)(4), Dembele D(1)(2)(3)(4), Capponi S(6), Timmers HTM(6), Vincent SD(1)(2)(3)(4), Tora L(7)(8)(9)(10).

  Nat Commun April 15, 2019;10:1740.

• Uniform Widespread Nuclear Phosphorylation of Histone H2AX Is an Indicator of Lethal DNA Replication Stress.

  Moeglin E(1), Desplancq D(2), Conic S(3)(4)(5)(6), Oulad-Abdelghani M(7)(8)(9)(10), Stoessel A(11), Chiper M(12), Vigneron M(13), Didier P(14), Tora L(15)(16)(17)(18), Weiss E(19).

  Cancers (Basel) March 13, 2019;11:E355.

• A cell cycle-coordinated Polymerase II transcription compartment encompasses gene expression before global genome activation.

  Hadzhiev Y(1), Qureshi HK(1), Wheatley L(1), Cooper L(1), Jasiulewicz A(1), Van Nguyen H(2), Wragg JW(1), Poovathumkadavil D(1), Conic S(3)(4), Bajan S(5), Sik A(6)(7), Hutvagner G(5), Tora L(3)(4), Gambus A(1), Fossey JS(2), Muller F(8).

  Nat Commun Feb. 11, 2019;10:691.

• Electroporation of Labeled Antibodies to Visualize Endogenous Proteins and Posttranslational Modifications in Living Metazoan Cell Types.

  Conic S(1)(2)(3)(4), Desplancq D(4)(5), Tora L(1)(2)(3)(4), Weiss E(4)(5).

  Bio Protoc Nov. 5, 2018;8:10.21769/BioProtoc.3069.

• Terminal exon characterization with TECtool reveals an abundance of cell-specific isoforms.

  Gruber AJ(1), Gypas F(2), Riba A(3), Schmidt R(2), Zavolan M(4).

  Nat Methods Oct 2018;15:832-836.

• Multiple inputs ensure yeast cell size homeostasis during cell cycle progression.

  Garmendia-Torres C(1), Tassy O(1), Matifas A(1), Molina N(1), Charvin G(1).

  Elife July 4, 2018;7:e34025.

• Recapitulating early development of mouse musculoskeletal precursors of the paraxial mesoderm in vitro.

  Chal J(1)(2)(3)(4), Al Tanoury Z(1)(2)(3)(4), Oginuma M(1)(2)(3)(4), Moncuquet P(1), Gobert B(1)(5), Miyanari A(1), Tassy O(1), Guevara G(2)(3)(4), Hubaud A(1)(2)(3)(4), Bera A(1), Sumara O(1), Garnier JM(1), Kennedy L(1), Knockaert M(1)(2)(3)(4), Gayraud-Morel B(6)(7), Tajbakhsh S(6)(7), Pourquie O(8)(2)(3)(4).

  Development March 19, 2018;145:dev157339.