IGBMC : Institut de la Génétique et de la Biologie Moléculaire et Cellulaire

• Chercheurs

  Susan CHAN

  Céline CHARVET

  Beate HEIZMANN

  Philippe KASTNER

  Peggy KIRSTETTER

• Doctorants

  Chiara BERNARDI

  Giovanni COVA

  Marie-Céline DEAU

  Guillaume MOREL

  Célestine SIMAND

• Ingénieurs & Techniciens

  Patricia MARCHAL

• Master

  Lauriane LUTGEN

• Stagiaire

  Vincent MITTELHEISSER

Génomique fonctionnelle et cancer

Hématopoïèse et leucémogenèse chez la souris

Publications

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• CBP and P300 regulate distinct gene networks required for human primary myoblast differentiation and muscle integrity.

  Fauquier L(1), Azzag K(1)(2), Parra MAM(3), Quillien A(1), Boulet M(1)(4), Diouf S(1)(4), Carnac G(5), Waltzer L(1)(4), Gronemeyer H(3), Vandel L(6)(7).

  Sci Rep 22 août 2018;8:12629.

• Ikaros cooperates with Notch activation and antagonizes TGFbeta signaling to promote pDC development.

  Mastio J(1), Simand C(1), Cova G(1), Kastner P(1)(2), Chan S(1), Kirstetter P(1).

  PLoS Genet 12 juillet 2018;14:e1007485.

• Severe combined immunodeficiency in stimulator of interferon genes (STING) V154M/wild-type mice.

  Bouis D(1), Kirstetter P(2), Arbogast F(3), Lamon D(1), Delgado V(1), Jung S(4), Ebel C(2), Jacobs H(5), Knapp AM(6), Jeremiah N(7), Belot A(8), Martin T(9), Crow YJ(10), Andre-Schmutz I(11), Korganow AS(9), Rieux-Laucat F(12), Soulas-Sprauel P(13).

  J Allergy Clin Immunol 23 mai 2018.

• Requirement of GSK-3 for PUMA induction upon loss of pro-survival PI3K signaling.

  Schubert F(1)(2)(3), Rapp J(1)(3), Brauns-Schubert P(1)(2)(3)(4), Schlicher L(1)(2)(3)(4), Stock K(1)(3), Wissler M(1), Wei M(1), Charvet C(5), Borner C(1)(2)(4), Maurer U(6)(7)(8).

  Cell Death Dis 23 avril 2018;9:470.

• Treatment of MCPT8DTR mice with high- or low-dose diphtheria toxin leads to differential depletion of basophils and granulocyte-macrophage progenitors.

  El Hachem C(1), Hener P(1), Kirstetter P(1), Li J(1), Chan S(1), Li M(1).

  Eur J Immunol May 2018;48:861-873.

• The Ikaros family in lymphocyte development.

  Heizmann B(1), Kastner P(2), Chan S(3).

  Curr Opin Immunol Apr 2018;51:14-23.

• Therapeutical modulation of plasmacytoid dendritic cells in experimental arthritis.

  Nehmar R(1)(2), Alsaleh G(1)(2), Voisin B(3), Flacher V(3), Mariotte A(1)(2), Saferding V(4), Puchner A(4), Niederreiter B(4), Vandamme T(5), Schabbauer G(6), Kastner P(7), Chan S(7), Kirstetter P(7), Holcmann M(8), Mueller C(3), Sibilia J(1)(2), Bahram S(1)(2), Bluml S(4), Georgel P(1)(2).

  Arthritis Rheumatol Nov 2017;69:2124-2135.

• Helios expression coordinates the development of a subset of striatopallidal medium spiny neurons.

  Martin-Ibanez R(1)(2)(3)(4)(5), Pardo M(1)(2)(3)(4), Giralt A(3)(4)(6), Miguez A(1)(2)(3)(4), Guardia I(1)(2)(3)(4), Marion-Poll L(7), Herranz C(1)(2)(3)(4)(5), Esgleas M(1)(3)(4), Garcia-Diaz Barriga G(2)(3)(4)(6), Edel MJ(8)(9)(10), Vicario-Abejon C(4)(11), Alberch J(2)(3)(4), Girault JA(7), Chan S(1)(2), Kastner P(12)(13), Canals JM(14)(2)(3)(4)(5).

  Development 15 avril 2017;144:1566-1577.