IGBMC : Institut de la Génétique et de la Biologie Moléculaire et Cellulaire

• Chercheurs

  Hinrich GRONEMEYER

  Marco Antonio MENDOZA PARRA

• Post-Doctorants

  Akinchan KUMAR

• Ingénieurs & Techniciens

  Alaa BADREDDINE

  Cathie ERB

  Michèle LIEB

  Samuel NICAISE

• Master

  Virginia DAVOLIO

  François STUDER

Génomique fonctionnelle et cancer

Biologie des systèmes des décisions du destin cellulaire dans les cellules normales et tumorales

Publications

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• Reconstructed cell fate-regulatory programs in stem cells reveal hierarchies and key factors of neurogenesis.

  Mendoza-Parra MA(1), Malysheva V(1), Mohamed Saleem MA(1), Lieb M(1), Godel A(1), Gronemeyer H(1).

  Genome Res Nov 2016;26:1505-1519.

• Antibody performance in ChIP-sequencing assays: From quality scores of public data sets to quantitative certification.

  Mendoza-Parra MA1, Saravaki V1, Cholley PE1, Blum M1, Billoré B1, Gronemeyer H1.

  Version 2. F1000Res. jan 2016;11:54.

• Reconstruction of gene regulatory networks reveals chromatin remodelers and key transcription factors in tumorigenesis.

  Malysheva V(1), Mendoza-Parra MA(1), Saleem MA(1), Gronemeyer H(2).

  Genome Med 19 mai 2016;8:57.

• NGS-QC Generator: A Quality Control System for ChIP-Seq and Related Deep Sequencing-Generated Datasets.

  Mendoza-Parra MA(1), Saleem MA(2), Blum M(2), Cholley PE(2), Gronemeyer H(2).

  Methods Mol Biol 2016;1418:243-65.

• TARDIS, a targeted RNA directional sequencing method for rare RNA discovery.

  Portal MM(1), Pavet V(1), Erb C(1), Gronemeyer H(1).

  Nat Protoc Dec 2015;10:1915-38.

• Modulation of Retinoic Acid Receptor Subtypes by 5- and 8-Substituted (Naphthalen-2-yl)-based Arotinoids.

  Álvarez S(1), Lieb M(2), Martínez C(1), Khanwalkar H(2), Rodríguez-Barrios F(1), Álvarez R(3), Gronemeyer H(4), de Lera AR(5).

  ChemMedChem Aug 2015;10:1378-91.

• An Unexpected Mode Of Binding Defines BMS948 as A Full Retinoic Acid Receptor beta (RARbeta, NR1B2) Selective Agonist.

  Nadendla E(1), Teyssier C(2), Delfosse V(2), Vivat V(3), Krishnasamy G(4), Gronemeyer H(5), Bourguet W(2), Germain P(2).

  PLoS One 1 mai 2015;10:e0123195.

• The inactive X chromosome is epigenetically unstable and transcriptionally labile in breast cancer.

  Chaligné R(1), Popova T(2), Mendoza-Parra MA(3), Saleem MA(3), Gentien D(4), Ban K(1), Piolot T(5), Leroy O(5), Mariani O(6), Gronemeyer H(7), Vincent-Salomon A(8), Stern MH(9), Heard E(10).

  Genome Res Apr 2015;25:488-503.