IGBMC : Institut de la Génétique et de la Biologie Moléculaire et Cellulaire

• Chercheurs

  Hinrich GRONEMEYER

  Marco Antonio MENDOZA PARRA

• Post-Doctorants

  Akinchan KUMAR

• Ingénieurs & Techniciens

  Alaa BADREDDINE

  Cathie ERB

  Michèle LIEB

  Samuel NICAISE

• Master

  Virginia DAVOLIO

Génomique fonctionnelle et cancer

Biologie des systèmes des décisions du destin cellulaire dans les cellules normales et tumorales

Publications

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• Enantioselective apoptosis induction in histiocytic lymphoma cells and acute promyelocytic leukemia cells.

  Ivanova D, Gronemeyer H, Steinberg P, Nau H.

  Arch Toxicol Feb 2013;87:303-10.

• Sequential chromatin immunoprecipitation protocol for global analysis through massive parallel sequencing (reChIP-seq)

  Mendoza-Parra Marco Antonio , Pattabhiraman Shankaranarayanan Gronemeyer Hinrich

  PROTOCOL EXCHANGE 2012 2012;:.

• Indole-derived psammaplin A analogues as epigenetic modulators with multiple inhibitory activities.

  Pereira R(1), Benedetti R, Pérez-Rodríguez S, Nebbioso A, García-Rodríguez J, Carafa V, Stuhldreier M, Conte M, Rodríguez-Barrios F, Stunnenberg HG, Gronemeyer H, Altucci L, de Lera AR.

  J Med Chem 26 novembre 2012;55:9467-91.

• Disila-analogues of the synthetic retinoids EC23 and TTNN: synthesis, structure and biological evaluation.

  Gluyas JB(1), Burschka C, Dörrich S, Vallet J, Gronemeyer H, Tacke R.

  Org Biomol Chem 14 septembre 2012;10:6914-29.

• Modulation of RXR function through ligand design.

  Pérez E(1), Bourguet W, Gronemeyer H, de Lera AR.

  Biochim Biophys Acta Jan 2012;1821:57-69.

• A DNA methyltransferase modulator inspired by peyssonenyne natural product structures.

  García-Domínguez P(1), Weiss M, Lepore I, Álvarez R, Altucci L, Gronemeyer H, de Lera ÁR.

  ChemMedChem Dec 2012;7:2101-12.

• Single-tube linear DNA amplification for genome-wide studies using a few thousand cells.

  Shankaranarayanan P(1), Mendoza-Parra MA, van Gool W, Trindade LM, Gronemeyer H.

  Nat Protoc 26 janvier 2012;7:328-38.

• POLYPHEMUS: R package for comparative analysis of RNA polymerase II ChIP-seq profiles by non-linear normalization.

  Mendoza-Parra MA(1), Sankar M, Walia M, Gronemeyer H.

  Nucleic Acids Res Feb 2012;40:e30.