Transcription and mRNA export machineries SAGA and TREX-2 maintain monoubiquitinated H2B balance required for DNA repair.
Evangelista FM(1)(2)(3)(4), Maglott-Roth A(1)(2)(3)(4), Stierle M(1)(2)(3)(4), Brino L(1)(2)(3)(4), Soutoglou E(5)(2)(3)(4), Tora L(6)(2)(3)(4).
J Cell Biol 27 juillet 2018
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Genes and Pathways Regulated by Androgens in Human Neural Cells, Potential Candidates for the Male Excess in Autism Spectrum Disorder.
Quartier A(1), Chatrousse L(2), Redin C(1), Keime C(1), Haumesser N(1), Maglott-Roth A(1), Brino L(1), Le Gras S(1), Benchoua A(2), Mandel JL(3), Piton A(4).
Biol Psychiatry 15 août 2018
; 84:239-252
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A molecular roadmap for the emergence of early-embryonic-like cells in culture.
Rodriguez-Terrones D(1)(2), Gaume X(1)(2), Ishiuchi T(1)(3), Weiss A(2), Kopp A(2), Kruse K(4), Penning A(1), Vaquerizas JM(4), Brino L(2), Torres-Padilla ME(5)(6).
Nat Genet Jan 2018
; 50:106-119
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ISCA1 is essential for mitochondrial Fe4S4 biogenesis in vivo.
Beilschmidt LK(1,)(2,)(3,)(4,)(5), Ollagnier de Choudens S(6,)(7,)(8), Fournier M(1,)(2,)(3,)(4), Sanakis I(9), Hograindleur MA(6,)(7,)(8,)(10), Clemancey M(7,)(8,)(10), Blondin G(7,)(8,)(10), Schmucker S(1,)(2,)(3,)(4,)(5), Eisenmann A(1,)(2,)(3,)(4,)(5), Weiss A(1,)(2,)(3,)(4), Koebel P(1,)(2,)(3,)(4), Messaddeq N(1,)(2,)(3,)(4), Puccio H(1,)(2,)(3,)(4,)(5), Martelli A(1,)(2,)(3,)(4,)(5).
Nat Commun 11 mai 2017
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Transcription without XPB Establishes a Unified Helicase-Independent Mechanism of Promoter Opening in Eukaryotic Gene Expression.
Alekseev S(1), Nagy Z(1), Sandoz J(1), Weiss A(1), Egly JM(1), Le May N(1), Coin F(2).
Mol Cell 2 février 2017
; 65:504-514
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Ubiquitin Receptor Protein UBASH3B Drives Aurora B Recruitment to Mitotic Microtubules.
Krupina K(1), Kleiss C(1), Metzger T(1), Fournane S(1), Schmucker S(1), Hofmann K(2), Fischer B(1), Paul N(3), Porter IM(4), Raffelsberger W(5), Poch O(6), Swedlow JR(4), Brino L(1), Sumara I(7).
Dev Cell 11 janvier 2016
; 36:63-78
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Temporal and Spatial Uncoupling of DNA Double Strand Break Repair Pathways within Mammalian Heterochromatin.
Tsouroula K(1), Furst A(1), Rogier M(1), Heyer V(1), Maglott-Roth A(1), Ferrand A(2), Reina-San-Martin B(3), Soutoglou E(4).
Mol Cell 5 juillet 2016
; 63:293-305
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A targeted functional RNA interference screen uncovers glypican 5 as an entry factor for hepatitis B and D viruses.
Verrier ER(1,)(2), Colpitts CC(1,)(2), Bach C(1,)(2), Heydmann L(1,)(2), Weiss A(3), Renaud M(3), Durand SC(1,)(2), Habersetzer F(4), Durantel D(5), Abou-Jaoudé G(6), López Ledesma MM(7), Felmlee DJ(1,)(2), Soumillon M(8), Croonenborghs T(9,)(10), Pochet N(9), Nassal M(11), Schuster C(1,)(2), Brino L(3), Sureau C(6), Zeisel MB(1,)(2), Baumert TF(1,)(2,)(4).
Hepatology Jan 2016
; 63:35-48
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PI4K-beta and MKNK1 are regulators of hepatitis C virus IRES-dependent translation.
Lupberger J(1,)(2), Casanova C(3), Fischer B(4), Weiss A(4), Fofana I(1,)(2), Fontaine N(1,)(2), Fujiwara T(5), Renaud M(4), Kopp A(4), Schuster C(1,)(2), Brino L(4), Baumert TF(1,)(2,)(6), Thoma C(3).
Sci Rep 1 septembre 2015
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The Nuclear Oncogene SET Controls DNA Repair by KAP1 and HP1 Retention to Chromatin.
Kalousi A(1), Hoffbeck AS(1), Selemenakis PN(2), Pinder J(3), Savage KI(4), Khanna KK(4), Brino L(1), Dellaire G(3), Gorgoulis VG(5), Soutoglou E(6).
Cell Rep 7 avril 2015
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A high-throughput chemical screen with FDA approved drugs reveals that the antihypertensive drug Spironolactone impairs cancer cell survival by inhibiting homology directed repair.
Shahar OD(1), Kalousi A(2), Eini L(1), Fisher B(2), Weiss A(2), Darr J(1), Mazina O(3), Bramson S(4), Kupiec M(4), Eden A(1), Meshorer E(1), Mazin AV(3), Brino L(2), Goldberg M(5), Soutoglou E(6).
Nucleic Acids Res May 2014
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A small molecule screen identifies an inhibitor of DNA repair inducing the degradation of TFIIH and the chemosensitization of tumor cells to platinum.
Alekseev S(1), Ayadi M(2), Brino L(1), Egly JM(1), Larsen AK(2), Coin F(3).
Chem Biol 20 mars 2014
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The human TREX-2 complex is stably associated with the nuclear pore basket.
Umlauf D(1), Bonnet J, Waharte F, Fournier M, Stierle M, Fischer B, Brino L, Devys D, Tora L.
J Cell Sci 15 juin 2013
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HRas Signal Transduction Promotes Hepatitis C Virus Cell Entry by Triggering Assembly of the Host Tetraspanin Receptor Complex.
Zona L, Lupberger J, Sidahmed-Adrar N, Thumann C, Harris HJ, Barnes A, Florentin J, Tawar RG, Xiao F, Turek M, Durand SC, Duong FH, Heim MH, Cosset FL, Hirsch I, Samuel D, Brino L, Zeisel MB, Le Naour F, McKeating JA, Baumert TF.
Cell Host Microbe 13 mars 2013
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Pyridylthiourea-grafted polyethylenimine offers an effective assistance to siRNA-mediated gene silencing in vitro and in vivo.
Creusat G(1), Thomann JS, Maglott A, Pons B, Dontenwill M, Guérin E, Frisch B, Zuber G.
J Control Release 10 février 2012
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The nucleoporin 153, a novel factor in double-strand break repair and DNA damage response.
Lemaitre C(1), Fischer B, Kalousi A, Hoffbeck AS, Guirouilh-Barbat J, Shahar OD, Genet D, Goldberg M, Betrand P, Lopez B, Brino L, Soutoglou E.
Oncogene 8 novembre 2012
; 31:4803-9
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Large scale genotype comparison of human papillomavirus e2-host interaction networks provides new insights for e2 molecular functions.
Muller M, Jacob Y, Jones L, Weiss A, Brino L, Chantier T, Lotteau V, Favre M, Demeret C.
PLoS Pathog Jun 2012
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The SRA protein UHRF1 promotes epigenetic crosstalks and is involved in prostate cancer progression.
Babbio F, Pistore C, Curti L, Castiglioni I, Kunderfranco P, Brino L, Oudet P, Seiler R, Thalman GN, Roggero E, Sarti M, Pinton S, Mello-Grand M, Chiorino G, Catapano CV, Carbone GM, Bonapace IM.
Oncogene 15 novembre 2012
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Cullin 3 mediates SRC-3 ubiquitination and degradation to control the retinoic
acid response.
Ferry C, Gaouar S, Fischer B, Boeglin M, Paul N, Samarut E, Piskunov A,
Pankotai-Bodo G, Brino L, Rochette-Egly C.
Proc Natl Acad Sci U S A 20 décembre 2011
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EGFR and EphA2 are host factors for hepatitis C virus entry and possible targets for antiviral therapy
Lupberger J., Zeisel M.B., Xiao F., Thumann C., Fofana I., Zona L., Davis C., Mee C.J., Turek M., Gorke S., Royer C., Fischer B., Zahid M.N., Lavillette D., Fresquet J., Cosset F.L., Rothenberg S.M., Pietschmann T., Patel A.H., Pessaux P., Doffoel M., Raffelsberger W., Poch O., McKeating J.A., Brino L., Baumert T.F.
Nat Med May 2011
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alpha5beta1 integrin antagonists reduce chemotherapy-induced premature senescence and facilitate apoptosis in human glioblastoma cells.
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Int J Cancer 1 septembre 2010
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E6 proteins from diverse papillomaviruses self-associate both in vitro and in vivo.
Zanier K(1), Ruhlmann C, Melin F, Masson M, Ould M'hamed Ould Sidi A, Bernard X, Fischer B, Brino L, Ristriani T, Rybin V, Baltzinger M, Vande Pol S, Hellwig P, Schultz P, Trave G.
J Mol Biol 12 février 2010
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Nondenaturing chemical proteomics for protein complex isolation and identification
Budin G., Moune-Dimala M., Leriche G., Saliou J.M., Papillon J., Sanglier-Cianferani S., Van Dorsselaer A., Lamour V., Brino L., Wagner A.
Chembiochem 22 novembre 2010
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A chemical labeling strategy for proteomics under nondenaturing conditions
Budin G., Dimala M.M., Lamour V., Oudet P., Mioskowski C., Meunier S., Brino L., Wagner A.
Chembiochem 4 janvier 2010
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Optimization of the Azobenzene Scaffold for Reductive Cleavage by Dithionite; Development of an Azobenzene Cleavable Linker for Proteomic Applications
Leriche G, Budin G, Brino L, Wagner A
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RNAi: a powerful tool to unravel hepatitis C virus-host interactions within the
infectious life cycle.
Lupberger J, Brino L, Baumert TF.
J Hepatol Mar 2008
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RReportGenerator: automatic reports from routine statistical analysis using R
Raffelsberger W., Krause Y., Moulinier L., Kieffer D., Morand A.L., Brino L., Poch O.
Bioinformatics 15 janvier 2008
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The PHD Domain of Np95 (mUHRF1) Is Involved in Large-Scale Reorganization of Pericentromeric Heterochromatin
Papait R., Pistore C., Grazini U., Babbio F., Cogliati S., Pecoraro D., Brino L., Morand A.L., Dechampesme A.M., Spada F., Leonhardt H., McBlane F., Oudet P., Bonapace I.M.
Mol Biol Cell Aug 2008
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A DNA microarray for fission yeast: minimal changes in global gene expression
after temperature shift.
Xue Y, Haas SA, Brino L, Gusnanto A, Reimers M, Talibi D, Vingron M, Ekwall K,
Wright AP.
Yeast 15 janvier 2004
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A novel design of whole-genome microarray probes for Saccharomyces cerevisiae
which minimizes cross-hybridization.
Talla E, Tekaia F, Brino L, Dujon B.
BMC Genomics 22 septembre 2003
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Localization of the yeast RNA polymerase I-specific subunits
Bischler N., Brino L., Carles C., Riva M., Tschochner H., Mallouh V., Schultz P.
Embo J 2002
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Dimerization of Escherichia coli DNA-gyrase B provides a structural mechanism for activating the ATPase catalytic center
Brino L., Urzhumtsev A., Mousli M., Bronner C., Mitschler A., Oudet P., Moras D.
J Biol Chem 2000
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Isoleucine 10 is essential for DNA gyrase B function in escherichia coli
Brino L., Bronner C., Oudet P., Mousli M.
Biochimie 1999
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Expression in Escherichia coli of Y5 mutant and N-terminal domain- deleted DNA gyrase B proteins affects strongly plasmid maintenance
Brino L., Mousli M., Oudet P., Weiss E.
Plasmid 1998
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Expression in Escherichia coli of Y5-mutant and N-terminal domain- deleted DNA gyrase B proteins affects strongly plasmid maintenance
Brino L., Mousli M., Oudet P., Weiss E.
Plasmid 1997
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