IGBMC : Institut de la Génétique et de la Biologie Moléculaire et Cellulaire

• Scientific Referee

  Ngoc Hoan NGUYEN

• Engineers & Technicians

  Tat Cheung CHENG

  Alexandre DURAND

  Florence GRANGER

  Alain LITT

  Alastair MC EWEN

  Marie-Christine POTERSZMAN

  Pierre POUSSIN-COURMONTAGNE

• Catherine BIRCK

Technology platforms

Structural biology & genomics

Publications

Year : Page :

• Modulation of RXR-DNA complex assembly by DNA context.

  Osz J(1), McEwen AG(1), Wolf J(1), Poussin-Courmontagne P(1), Peluso-Iltis C(1), Chebaro Y(1), Kieffer B(2), Rochel N(3).

  Mol Cell Endocrinol Fev 5 2019

• CASQ1 mutations impair calsequestrin polymerization and cause tubular aggregate myopathy.

  Bohm J(1), Lornage X(2), Chevessier F(3), Birck C(2), Zanotti S(4), Cudia P(5), Bulla M(6), Granger F(2), Bui MT(7), Sartori M(2), Schneider-Gold C(8), Malfatti E(7), Romero NB(7), Mora M(4), Laporte J(9).

  Acta Neuropathol Jan 2018

• Biophysical analysis of Arabidopsis protein-only RNase P alone and in complex with tRNA provides a refined model of tRNA binding.

  Pinker F(1)(2), Schelcher C(2), Fernandez-Millan P(1), Gobert A(2), Birck C(3), Thureau A(4), Roblin P(4)(5), Giege P(6), Sauter C(7).

  J Biol Chem Aug. 25, 2017

• Dissecting mechanism of coupled folding and binding of an intrinsically disordered protein by chemical synthesis of conformationally constrained analogues.

  Schmidtgall B(1), Chaloin O, Bauer V, Sumyk M, Birck C, Torbeev V.

  Chem Commun (Camb) June 29, 2017

• Dynamics of Methylated Cytosine Flipping by UHRF1.

  Kilin V(1), Gavvala K(1), Barthes NP(2), Michel BY(2), Shin D(3), Boudier C(1), Mauffret O(4), Yashchuk V(5), Mousli M(1), Ruff M(6), Granger F(6), Eiler S(6), Bronner C(6), Tor Y(7), Burger A(2), Mely Y(1).

  J Am Chem Soc Feb. 15, 2017

• The crystal structure of the 5 functional domain of the transcription riboregulator 7SK.

  Martinez-Zapien D(1), Legrand P(2), McEwen AG(3)(4)(5)(6), Proux F(7)(8), Cragnolini T(9), Pasquali S(10), Dock-Bregeon AC(7)(8)(11)(12).

  Nucleic Acids Res April 7, 2017

• XPR1 mutations are a rare cause of primary familial brain calcification.

  Anheim M(1,)(2,)(3), Lopez-Sanchez U(4,)(5,)(6,)(7), Giovannini D(4,)(5,)(6,)(7), Richard AC(8,)(9,)(10), Touhami J(4,)(5,)(6,)(7), N'Guyen L(1,)(2,)(3), Rudolf G(1,)(2,)(3), Thibault-Stoll A(1), Frebourg T(8,)(9,)(11), Hannequin D(8,)(9,)(10,)(11,)(12), Campion D(8,)(9,)(10,)(13), Battini JL(14,)(15,)(16,)(17), Sitbon M(18,)(19,)(20,)(21), Nicolas G(22,)(23,)(24,)(25).

  J Neurol Aug 2016

• BTG2 bridges PABPC1 RNA-binding domains and CAF1 deadenylase to control cell proliferation.

  Stupfler B, Birck C, Séraphin B, Mauxion F.

  Nat Commun Feb. 25, 2016