IGBMC : Institut de la Génétique et de la Biologie Moléculaire et Cellulaire

• Référent Scientifique

  Ngoc Hoan NGUYEN

• Ingénieurs & Techniciens

  Vincent DESSERICH

  Florence GRANGER

  Alain LITT

  Alastair MC EWEN

  Julio ORTIZ ESPINOZA

  Marie-Christine POTERSZMAN

  Pierre POUSSIN-COURMONTAGNE

  Mathieu SCHAEFFER

• Catherine BIRCK

  Luka VANDERVELDEN

Plateformes technologiques

Biologie et génomique structurale

Publications

Année : Page :

• CASQ1 mutations impair calsequestrin polymerization and cause tubular aggregate myopathy.

  Bohm J(1), Lornage X(2), Chevessier F(3), Birck C(2), Zanotti S(4), Cudia P(5), Bulla M(6), Granger F(2), Bui MT(7), Sartori M(2), Schneider-Gold C(8), Malfatti E(7), Romero NB(7), Mora M(4), Laporte J(9).

  Acta Neuropathol Jan 2018

• Biophysical analysis of Arabidopsis protein-only RNase P alone and in complex with tRNA provides a refined model of tRNA binding.

  Pinker F(1)(2), Schelcher C(2), Fernandez-Millan P(1), Gobert A(2), Birck C(3), Thureau A(4), Roblin P(4)(5), Giege P(6), Sauter C(7).

  J Biol Chem 25 août 2017

• Dissecting mechanism of coupled folding and binding of an intrinsically disordered protein by chemical synthesis of conformationally constrained analogues.

  Schmidtgall B(1), Chaloin O, Bauer V, Sumyk M, Birck C, Torbeev V.

  Chem Commun (Camb) 29 juin 2017

• Dynamics of Methylated Cytosine Flipping by UHRF1.

  Kilin V(1), Gavvala K(1), Barthes NP(2), Michel BY(2), Shin D(3), Boudier C(1), Mauffret O(4), Yashchuk V(5), Mousli M(1), Ruff M(6), Granger F(6), Eiler S(6), Bronner C(6), Tor Y(7), Burger A(2), Mely Y(1).

  J Am Chem Soc 15 février 2017

• The crystal structure of the 5 functional domain of the transcription riboregulator 7SK.

  Martinez-Zapien D(1), Legrand P(2), McEwen AG(3)(4)(5)(6), Proux F(7)(8), Cragnolini T(9), Pasquali S(10), Dock-Bregeon AC(7)(8)(11)(12).

  Nucleic Acids Res 7 avril 2017

• XPR1 mutations are a rare cause of primary familial brain calcification.

  Anheim M(1,)(2,)(3), Lopez-Sanchez U(4,)(5,)(6,)(7), Giovannini D(4,)(5,)(6,)(7), Richard AC(8,)(9,)(10), Touhami J(4,)(5,)(6,)(7), N'Guyen L(1,)(2,)(3), Rudolf G(1,)(2,)(3), Thibault-Stoll A(1), Frebourg T(8,)(9,)(11), Hannequin D(8,)(9,)(10,)(11,)(12), Campion D(8,)(9,)(10,)(13), Battini JL(14,)(15,)(16,)(17), Sitbon M(18,)(19,)(20,)(21), Nicolas G(22,)(23,)(24,)(25).

  J Neurol Aug 2016

• BTG2 bridges PABPC1 RNA-binding domains and CAF1 deadenylase to control cell proliferation.

  Stupfler B, Birck C, Séraphin B, Mauxion F.

  Nat Commun 25 février 2016

• TCTP contains a BH3-like domain, which instead of inhibiting, activates Bcl-xL.

  Thébault S(1,)(2), Agez M(1,)(3), Chi X(4,)(5), Stojko J(6), Cura V(1), Telerman SB(7,)(8), Maillet L(9), Gautier F(9,)(10), Billas-Massobrio I(1), Birck C(1), Troffer-Charlier N(1), Karafin T(2,)(3), Honoré J(3), Senff-Ribeiro A(2,)(3), Montessuit S(11), Johnson CM(8), Juin P(9,)(10), Cianférani S(6), Martinou JC(11), Andrews DW(4,)(5), Amson R(2,)(3), Telerman A(2,)(3), Cavarelli J(1).

  Sci Rep 27 janvier 2016