Regulation of DNA topology
Team Leader : Valerie LAMOUR
Department : Integrated structural biology
Valerie LAMOUR
Researcher
lamourv@igbmc.fr
Research team(s)
Research subgroup(s)
Publications
2026
Article in a journal
DNA deformability in sequence-dependent capture of E. coli gyrase
- Matthew Baker
- Haley Johnson
- Ryan Eckerty
- Jonathan Fogg
- Silvia Summers
- Marlène Vayssières
- Nils Marechal
- Valérie Lamour
- Wilma Olson
- Lynn Zechiedrich
Nature Communications
Article in a journal
DNA Topoisomerase II Mutations in Cancer: Structural Impact and Drug Response in High-grade Serous Ovarian Carcinoma
- Viola Mazzoleni
- Amélie Boichard
- Valérie Lamour
Journal of Molecular Biology ; Volume: 438 ; Page: 169384
Article in a journal
MYC modulates TOP2A diffusion to promote substrate detection and activity
- Donald Cameron
- Kathryn Jackson
- Alessia Loffreda
- Carl Möller
- Vladislav Kuzin
- Matteo Mazzocca
- Evanthia Iliopoulou
- Hallgerdur Kolbeinsdottir
- Andrej Paluda
- Evgeniya Pavlova
- Bea Jagodic
- Brian Saidel Lopez Duran
- Valérie Lamour
- Fredrik Westerlund
- Davide Mazza
- Laura Baranello
Nature Communications ; Volume: 17 ; Page: 2527
2025
Article in a journal
DNA topoisomerase I acts as supercoiling sensor for bacterial transcription elongation
- Vita Vidmar
- Céline Borde
- Lisa Bruno
- Nataliya Miropolskaya
- Maria Takacs
- Claire Batisse
- Charlotte Saint-André
- Chengjin Zhu
- Olivier Espéli
- Valerie Lamour
- Albert Weixlbaumer
Nature Structural and Molecular Biology
2024
Article in a journal
Structural basis of DNA crossover capture by Escherichia coli DNA gyrase
- Marlène Vayssières
- Nils Marechal
- Long Yun
- Brian Lopez Duran
- Naveen Kumar Murugasamy
- Jonathan Fogg
- Lynn Zechiedrich
- Marc Nadal
- Valérie Lamour
Science ; Volume: 384 ; Page: 227-232
2023
Article in a journal » Review article
What’s on the Other Side of the Gate: A Structural Perspective on DNA Gate Opening of Type IA and IIA DNA Topoisomerases
- Vita Vidmar
- Marlène Vayssières
- Valérie Lamour
International Journal of Molecular Sciences ; Volume: 24 ; Page: 3986
2022
Article in a journal
The human RNA polymerase I structure reveals an HMG-like docking domain specific to metazoans
- Julia L Daiß
- Michael Pilsl
- Kristina Straub
- Andrea Bleckmann
- Mona Höcherl
- Florian B Heiss
- Guillermo Abascal-Palacios
- Ewan P Ramsay
- Katarina Tlučková
- Jean-Clement Mars
- Torben Fürtges
- Astrid Bruckmann
- Till Rudack
- Carrie Bernecky
- Valérie Lamour
- Konstantin Panov
- Alessandro Vannini
- Tom Moss
- Christoph Engel
Life Science Alliance ; Volume: 5 ; Page: e202201568
2021
Article in a journal
Structural basis for allosteric regulation of Human Topoisomerase IIα
- Arnaud Vanden Broeck
- Christophe Lotz
- Robert Drillien
- Léa Haas
- Claire Bedez
- Valérie Lamour
Nature Communications ; Volume: 12
Article in a journal
Exonuclease VII repairs quinolone-induced damage by resolving DNA gyrase cleavage complexes
- Shar-Yin N. Huang
- Stephanie A. Michaels
- Brianna B. Mitchell
- Nadim Majdalani
- Arnaud Vanden Broeck
- Andres Canela
- Yuk-Ching Tse-Dinh
- Valérie Lamour
- Yves Pommier
Science Advances ; Volume: 7 ; Page: eabe0384
2020
Article in a journal
Structural and Functional Studies of Human Type II Topoisomerases and their Post-Translational Modifications
- Christophe Lotz
- Claire Bedez
- Claire Batisse
- Arnaud Vanden Broeck
- Robert Drillien
- Marc Ruff
- Valerie Lamour
Biophysical Journal ; Volume: 118 ; Page: 532a