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Antinociceptive Effects of Potent, Selective and Brain Penetrant Muscarinic M4 Positive Allosteric Modulators in Rodent Pain Models.
Grauer SM(1), Sanoja R(2), Poulin D(3), Rashid H(3), Jochnowitz N(4), Calhoun M(4), Zwilling D(4), Varty GB(4), Rosahl TW(4), Meziane H(5), Mittlelhaeuser C(5), Mazzola R(4), Morrow J(2), Smith SM(2), Henze D(2), Marcus J(2).
Brain Res Mar 29:146814 2020
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Aralar Sequesters GABA into Hyperactive Mitochondria, Causing Social Behavior Deficits.
Kanellopoulos AK(1), Mariano V(2), Spinazzi M(3), Woo YJ(4), McLean C(5), Pech U(6), Li KW(7), Armstrong JD(8), Giangrande A(9), Callaerts P(10), Smit AB(7), Abrahams BS(11), Fiala A(6), Achsel T(1), Bagni C(12).
Cell March 19, 2020
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A rare codon-based translational program of cell proliferation.
Guimaraes JC(1), Mittal N(2), Gnann A(2)(3), Jedlinski D(2), Riba A(2)(4), Buczak K(5), Schmidt A(5), Zavolan M(6).
Genome Biol Feb. 27, 2020
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Ascl1 is required to specify a subset of ventromedial hypothalamic neurons.
Aslanpour S(1)(2)(3), Rosin JM(4)(2)(3), Balakrishnan A(5), Klenin N(4)(2)(3), Blot F(6), Gradwohl G(6), Schuurmans C(5), Kurrasch DM(7)(4)(2)(3).
Development April 6, 2020
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A Small Compound Targeting Prohibitin with Potential Interest for Cognitive Deficit Rescue in Aging mice and Tau Pathology Treatment.
Guyot AC(1), Leuxe C(1), Disdier C(1)(2), Oumata N(3), Costa N(1), Roux GL(1), Fernandez-Varela P(4), Duchon A(5), Charbonnier JB(4), Herault Y(5), Pavoni S(6), Galons H(3), Andriambeloson E(7), Wagner S(7), Meijer L(8), Lund AK(9), Mabondzo A(10).
Sci Rep Jan. 24, 2020
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BAHD1 haploinsufficiency results in anxiety-like phenotypes in male mice.
Pourpre R(1), Naudon L(1)(2), Meziane H(3), Lakisic G(1), Jouneau L(4), Varet H(5)(6), Legendre R(5)(6), Wendling O(3), Selloum M(3), Proux C(6), Coppée JY(6), Herault Y(3)(7), Bierne H(1).
PLoS One May 14, 2020
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Benign hereditary chorea: From benign to serious.
Lamiral A(1), El Chehadeh S(2), Chelly J(3), Anheim M(4), Laugel V(5), Tranchant C(4).
Rev Neurol (Paris) Jan. 23, 2020
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Blood Flow Limits Endothelial Cell Extrusion in the Zebrafish Dorsal Aorta.
Campinho P(1), Lamperti P(1), Boselli F(1), Vilfan A(2), Vermot J(3).
Cell Rep April 14, 2020
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