Différenciation et physiopathologie des cellules endocrines pancréatiques et intestinales
Chef d'équipe : Gerard GRADWOHL
Département : Biologie du développement et cellules souches
Gerard GRADWOHL
Chercheur
gradwohl@igbmc.fr
Équipe(s)
Publications
2016
Article dans une revue
STAT3 modulates β-cell cycling in injured mouse pancreas and protects against DNA damage
- S de Groef
- D Renmans
- Y Cai
- G Leuckx
- S Roels
- W Staels
- G Gradwohl
- L Baeyens
- Y Heremans
- G Martens
- N de Leu
- M Sojoodi
- M van de Casteele
- H Heimberg
Cell Death and Disease ; Volume: 7 ; Page: e2272-e2272
Article dans une revue
Expression and functional studies of the GDNF family receptor alpha 3 in the pancreas
- Laure Nivlet
- Joel Herrmann
- Delia Esteban Martin
- Aline Meunier
- Christophe Orvain
- Gérard Gradwohl
Journal of Molecular Endocrinology ; Volume: 56 ; Page: 77-90
2015
Article dans une revue
Differentially Expressed MicroRNA-483 Confers Distinct Functions in Pancreatic β- and α-Cells
- Ramkumar Mohan
- Yiping Mao
- Shungang Zhang
- Yu-Wei Zhang
- Cheng-Ran Xu
- Gérard Gradwohl
- Xiaoqing Tang
Journal of Biological Chemistry ; Volume: 290 ; Page: 19955-19966
Article dans une revue
Pairing-up SOX to kick-start beta cell genesis
- Anne Grapin-Botton
- Philip Allan Seymour
- Gerard Gradwohl
Diabetologia ; Volume: 58 ; Page: 859-861
2014
Article dans une revue
Pak3 promotes cell cycle exit and differentiation of β-cells in the embryonic pancreas and is necessary to maintain glucose homeostasis in adult mice.
- Julie Piccand
- Aline Meunier
- Carole Merle
- Zhengping Jia
- Jean-Vianney Barnier
- Gérard Gradwohl
Diabetes ; Volume: 63 ; Page: 203-15
Article dans une revue
Rfx6 Maintains the Functional Identity of Adult Pancreatic β Cells
- Julie Piccand
- Perrine Strasser
- David J. Hodson
- Aline Meunier
- Tao Ye
- Céline Keime
- Marie-Christine Birling
- Guy A. Rutter
- Gérard Gradwohl
Cell Reports ; Volume: 9 ; Page: 2219-2232
2013
Article dans une revue
Conditional deletion of neurogenin-3 using Nkx2.1iCre results in a mouse model for the central control of feeding, activity and obesity
- Neal Anthwal
- Michelle Pelling
- Suzanne Claxton
- Georg Mellitzer
- Caitlin Collin
- Nicoletta Kessaris
- William D Richardson
- Gérard Gradwohl
- Siew-Lan Ang
Disease Models & Mechanisms
2012
Article dans une revue
The homeodomain-containing transcription factors Arx and Pax4 control enteroendocrine subtype specification in mice.
- Anthony Beucher
- Elisabet Gjernes
- Caitlin Collin
- Monica Courtney
- Aline Meunier
- Patrick Collombat
- Gérard Gradwohl
PLoS ONE ; Volume: 7 ; Page: e36449
Article dans une revue
Competence of failed endocrine progenitors to give rise to acinar but not ductal cells is restricted to early pancreas development
- Anthony Beucher
- Mercè Martin
- Caroline Spenle
- Martine Poulet
- Caitlin Collin
- Gerard Gradwohl
Developmental biology ; Volume: 361 ; Page: 277-285
Article dans une revue
Pancreatic islet and progenitor cell surface markers with cell sorting potential
- J Hald
- T Galbo
- C Rescan
- L Radzikowski
- A Sprinkel
- H Heimberg
- J Ahnfelt-Ronne
- J Jensen
- R Scharfmann
- Gerard Gradwohl
- K H Kaestner
- C Stoeckert
- J N Jensen
- O D Madsen
Diabetologia ; Volume: 55 ; Page: 154-165