Translating Triple Negative Breast Cancer and extracellular matrix interface from genetically diverse patients

Le 19 mai 2025 à 11h00 Séminaire

The overreaching focus of our research is to define breast cancer signaling events involving epithelial mesenchymal transitions (EMT) and the role of the extracellular matrix (ECM) that drives tumor initiation, proliferation and metastasis. The primary goals of our research involve 1) mammary gland development, 2) evaluation of ECM remodeling and the effects of EMT during breast cancer progression, and 3) investigating the occurrence of invasive breast cancer by analyzing ancestry dependent variations.