Biologie moléculaire et cellulaire des cancers du sein
Cheffe d'équipe : Catherine-Laure TOMASETTO
Département : Génomique fonctionnelle et cancer
Fabien ALPY
Chercheur
falpy@igbmc.fr
Équipe(s)
Fabien Alpy est directeur de recherche Inserm. Il étudie la biologie des cellules de cancer du sein, et s’intéresse en particulier aux interactions physiques entre les organites au sein de structure nommées sites de contact membranaire. Il cherche à comprendre l’organisation et la fonction des sites de contact, en particulier dans le transport intracellulaire des lipides, dans les cellules normales et les cellules cancéreuses du sein.
Publications
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2020
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Matrix Metalloproteinase-11 Promotes Early Mouse Mammary Gland Tumor Growth through Metabolic Reprogramming and Increased IGF1/AKT/FoxO1 Signaling Pathway, Enhanced ER Stress and Alteration in Mitochondrial UPR
- Bing Tan
- Amélie Jaulin
- Caroline Bund
- Hassiba Outilaft
- Corinne Wendling
- Marie-Pierrette Chenard
- Fabien Alpy
- A. Ercüment Cicek
- Izzie Namer
- Catherine Tomasetto
- Nassim Dali-Youcef
Cancers ; Volume: 12 ; Page: 2357
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Another hijack! Some enteroviruses co‐opt the c10orf76/ PI 4 KB complex for their own good
- Laetitia Voilquin
- Thomas Di Mattia
- Fabien Alpy
EMBO Reports ; Volume: 21
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Faraway, so close! Functions of Endoplasmic reticulum–Endosome contacts
- Thomas Di Mattia
- Catherine Tomasetto
- Fabien Alpy
Biochimica et Biophysica Acta Molecular and Cell Biology of Lipids ; Volume: 1865 ; Page: 158490
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The type 2 diabetes gene product STARD10 is a phosphoinositide-binding protein that controls insulin secretory granule biogenesis
- Gaelle Carrat
- Elizabeth Haythorne
- Alejandra Tomas
- Leena Haataja
- Andreas Müller
- Peter Arvan
- Alexandra Piunti
- Kaiying Cheng
- Mutian Huang
- Timothy Pullen
- Eleni Georgiadou
- Theodoros Stylianides
- Nur Shabrina Amirruddin
- Victoria Salem
- Walter Distaso
- Andrew Cakebread
- Kate Heesom
- Philip Lewis
- David Hodson
- Linford Briant
- ...
Molecular metabolism ; Volume: 40 ; Page: 101015
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Matrix Metalloproteinase-11 Promotes Early Mouse Mammary Gland Tumor Growth through Metabolic Reprogramming and Increased IGF1/AKT/FoxO1 Signaling Pathway, Enhanced ER Stress and Alteration in Mitochondrial UPR
- Bing Tan
- Amélie Jaulin
- Caroline Bund
- Hassiba Outilaft
- Corinne Wendling
- Marie-Pierrette Chenard
- Fabien Alpy
- A. Ercüment Cicek
- Izzie J Namer
- Catherine Tomasetto
- Nassim Dali-Youcef
Cancers ; Volume: 12 ; Page: 2357
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2019
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A novel machine learning-derived decision tree including uPA/PAI-1 for breast cancer care
- Nathalie Reix
- Massimo Lodi
- Stéphane Jankowski
- Sébastien Molière
- Elisabeth Luporsi
- Suzanne Leblanc
- Louise Scheer
- Issam Ibnouhsein
- Julie-Charlotte Benabu
- Victor Gabriele
- Alberto Guggiola
- Jean-Marc Lessinger
- Marie-Pierre Chenard
- Fabien Alpy
- Jean-Pierre Bellocq
- Karl Neuberger
- Catherine Tomasetto
- Carole Mathelin
Clinical Chemistry and Laboratory Medicine ; Volume: 57 ; Page: 901-910
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Intracellular and Plasma Membrane Cholesterol Labeling and Quantification Using Filipin and GFP-D4
- Léa Wilhelm
- Laetitia Voilquin
- Toshihide Kobayashi
- Catherine Tomasetto
- Fabien Alpy
Intracellular Lipid Transport ; Volume: 1949 ; Page: 137-152
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MOSPD2, un connecteur inter-organites, MOSPD2, an inter-organelle connector
- Thomas Di Mattia
- Catherine Tomasetto
- Fabien Alpy
Médecine/Sciences ; Volume: 35 ; Page: 23-25
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STARD3: A Swiss Army Knife for Intracellular Cholesterol Transport
- Laetitia Voilquin
- Massimo Lodi
- Thomas Di Mattia
- Marie-Pierre Chenard
- Carole Mathelin
- Fabien Alpy
- Catherine Tomasetto
Contact ; Volume: 2 ; Page: 251525641985673
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2018
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A Third Musketeer on the ER: MOSPD2 is a Novel VAP-related Receptor for FFAT Motifs
- Thomas Di Mattia
- Catherine Tomasetto
- Fabien Alpy
Contact ; Volume: 1 ; Page: Epub ahead of print
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