Natacha ROCHEL-GUIBERTEAU

Publications

• 2025

  • Design, synthesis and biological evaluation of a novel non-Gemini analog of UVB1 and crystal structure of its complex with the vitamin D receptor

    • Uxía Gómez-Bouzó
    • Carole Peluso-Iltis
    • Hugo Santalla
    • Lieve Verlinden
    • Annemieke Verstuyf
    • Natacha Rochel
    • Generosa Gómez
    • Yagamare Fall

    Bioorganic Chemistry ; Volume: 157 ; Page: 108239

    HAL DOI

  • Guanidinium‐Stapled Helical Peptides for Targeting Protein‐Protein Interactions

    • Camille Perdriau
    • Anaïs Luton
    • Katharina Zimmeter
    • Maxime Neuville
    • Claire Saragaglia
    • Carole Peluso-Iltis
    • Judit Osz
    • Brice Kauffmann
    • Gavin Collie
    • Natacha Rochel
    • Gilles Guichard
    • Morgane Pasco

    Angewandte Chemie International Edition ; Volume: 64 ; Page: e202416348

    HAL DOI

• 2024

  • First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity

    • Julian Loureiro
    • Samuel Seoane
    • Ivo Sampaio-Dias
    • Carole Peluso-Iltis
    • Thierry Guiberteau
    • Beatriz Brito
    • Carlos Gregorio
    • Román Pérez-Fernández
    • Natacha Rochel
    • Antonio Mouriño
    • José Rodríguez-Borges

    Journal of Medicinal Chemistry ; Volume: 67 ; Page: 21505-21519

    HAL DOI

  • Retinoids Molecular Probes by Late‐stage Azide Insertion – Functional Tools to Decrypt Retinoid Metabolism

    • Jessica Coulleray
    • Alexia Kindler
    • Mohamad Rima
    • Héloïse Cahuzac
    • Natacha Rochel
    • Guilhem Chaubet
    • Wojciech Krezel
    • Alain Wagner

    ChemBioChem ; Volume: 25 ; Page: e202300689

    HAL DOI

  • A vitamin D‐based strategy overcomes chemoresistance in prostate cancer

    • Kateryna Len‐tayon
    • Claire Beraud
    • Clara Fauveau
    • Anna Y Belorusova
    • Yassmine Chebaro
    • Antonio Mouriño
    • Thierry Massfelder
    • Anne Chauchereau
    • Daniel Metzger
    • Natacha Rochel
    • Gilles Laverny

    British Journal of Pharmacology ; Page: Online ahead of print

    HAL DOI

  • Design, Synthesis, and Biological Evaluation of New Type of Gemini Analogues with a Cyclopropane Moiety in Their Side Chain

    • Uxía Gómez-Bouzó
    • Carole Peluso-Iltis
    • Hugo Santalla
    • Mario Alfredo Quevedo
    • Lieve Verlinden
    • Annemieke Verstuyf
    • Yagamare Fall
    • Generosa Gómez
    • Natacha Rochel

    Journal of Medicinal Chemistry ; Volume: 67 ; Page: 10386-10400

    HAL DOI

  • Design, synthesis, and biological activity of D-bishomo-1α,25-dihydroxyvitamin D3 analogs and their crystal structures with the vitamin D nuclear receptor

    • Adrian Fabisiak
    • Pawel Brzeminski
    • Rafal Sicinski
    • Natacha Rochel
    • Ewa Maj
    • Beata Filip-Psurska
    • Joanna Wietrzyk
    • Lori Plum
    • Hector Deluca

    European Journal of Medicinal Chemistry ; Volume: 271 ; Page: 116403

    HAL DOI

  • 4-Hydroxy-1α,25-Dihydroxyvitamin D$_3$: Synthesis and Structure–Function Study

    • Carole Peluso-Iltis
    • Noé Pierrat
    • Daniela Rovito
    • Judit Osz
    • Daisuke Sawada
    • Atsushi Kittaka
    • Gilles Laverny
    • Natacha Rochel

    Biomolecules ; Volume: 14 ; Page: 551

    HAL DOI

• 2023

  • Further Studies on the Highly Active Des-C-Ring and Aromatic-D-Ring Analogues of 1,25-Dihydroxyvitamin D3 (Calcitriol): Refinement of the Side Chain

    • Araceli Zárate-Ruíz
    • Samuel Seoane
    • Carole Peluso-Iltis
    • Stefan Peters
    • Carlos Gregorio
    • Thierry Guiberteau
    • Miguel A Maestro
    • Román Pérez-Fernández
    • Natacha Rochel
    • Antonio Mouriño

    Journal of Medicinal Chemistry ; Volume: 66 ; Page: 15326-15339

    HAL DOI

  • Vitamin D Receptor Antagonist MeTC7 Inhibits PD-L1

    • Negar Khazan
    • Emily Quarato
    • Niloy Singh
    • Cameron Snyder
    • Taylor Moore
    • John Miller
    • Masato Yasui
    • Yuki Teramoto
    • Takuro Goto
    • Sabeeha Reshi
    • Jennifer Hong
    • Naixin Zhang
    • Diya Pandey
    • Priyanka Srivastava
    • Alexandra Morell
    • Hiroki Kawano
    • Yuko Kawano
    • Thomas Conley
    • Deepak Sahasrabudhe
    • Naohiro Yano
    • ...

    Cancers ; Volume: 15 ; Page: 3432

    HAL DOI