Chemical biophysics of transcriptional signaling
Team Leader : Annick DEJAEGERE
Department : Integrated structural biology
Natacha ROCHEL-GUIBERTEAU
Researcher
rochel@igbmc.fr
Research team(s)
Research subgroup(s)
Publications
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2025
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Guanidinium‐Stapled Helical Peptides for Targeting Protein‐Protein Interactions
- Camille Perdriau
- Anaïs Luton
- Katharina Zimmeter
- Maxime Neuville
- Claire Saragaglia
- Carole Peluso-Iltis
- Judit Osz
- Brice Kauffmann
- Gavin Collie
- Natacha Rochel
- Gilles Guichard
- Morgane Pasco
Angewandte Chemie International Edition ; Volume: 64 ; Page: e202416348
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2024
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First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity
- Julian Loureiro
- Samuel Seoane
- Ivo Sampaio-Dias
- Carole Peluso-Iltis
- Thierry Guiberteau
- Beatriz Brito
- Carlos Gregorio
- Román Pérez-Fernández
- Natacha Rochel
- Antonio Mouriño
- José Rodríguez-Borges
Journal of Medicinal Chemistry ; Volume: 67 ; Page: 21505-21519
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Retinoids Molecular Probes by Late‐stage Azide Insertion – Functional Tools to Decrypt Retinoid Metabolism
- Jessica Coulleray
- Alexia Kindler
- Mohamad Rima
- Héloïse Cahuzac
- Natacha Rochel
- Guilhem Chaubet
- Wojciech Krezel
- Alain Wagner
ChemBioChem ; Volume: 25 ; Page: e202300689
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A vitamin D‐based strategy overcomes chemoresistance in prostate cancer
- Kateryna Len‐tayon
- Claire Beraud
- Clara Fauveau
- Anna Y Belorusova
- Yassmine Chebaro
- Antonio Mouriño
- Thierry Massfelder
- Anne Chauchereau
- Daniel Metzger
- Natacha Rochel
- Gilles Laverny
British Journal of Pharmacology ; Page: Online ahead of print
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Design, Synthesis, and Biological Evaluation of New Type of Gemini Analogues with a Cyclopropane Moiety in Their Side Chain
- Uxía Gómez-Bouzó
- Carole Peluso-Iltis
- Hugo Santalla
- Mario Alfredo Quevedo
- Lieve Verlinden
- Annemieke Verstuyf
- Yagamare Fall
- Generosa Gómez
- Natacha Rochel
Journal of Medicinal Chemistry ; Volume: 67 ; Page: 10386-10400
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Design, synthesis, and biological activity of D-bishomo-1α,25-dihydroxyvitamin D3 analogs and their crystal structures with the vitamin D nuclear receptor
- Adrian Fabisiak
- Pawel Brzeminski
- Rafal Sicinski
- Natacha Rochel
- Ewa Maj
- Beata Filip-Psurska
- Joanna Wietrzyk
- Lori Plum
- Hector Deluca
European Journal of Medicinal Chemistry ; Volume: 271 ; Page: 116403
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4-Hydroxy-1α,25-Dihydroxyvitamin D$_3$: Synthesis and Structure–Function Study
- Carole Peluso-Iltis
- Noé Pierrat
- Daniela Rovito
- Judit Osz
- Daisuke Sawada
- Atsushi Kittaka
- Gilles Laverny
- Natacha Rochel
Biomolecules ; Volume: 14 ; Page: 551
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2023
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Further Studies on the Highly Active Des-C-Ring and Aromatic-D-Ring Analogues of 1,25-Dihydroxyvitamin D3 (Calcitriol): Refinement of the Side Chain
- Araceli Zárate-Ruíz
- Samuel Seoane
- Carole Peluso-Iltis
- Stefan Peters
- Carlos Gregorio
- Thierry Guiberteau
- Miguel A Maestro
- Román Pérez-Fernández
- Natacha Rochel
- Antonio Mouriño
Journal of Medicinal Chemistry ; Volume: 66 ; Page: 15326-15339
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Vitamin D Receptor Antagonist MeTC7 Inhibits PD-L1
- Negar Khazan
- Emily Quarato
- Niloy Singh
- Cameron Snyder
- Taylor Moore
- John Miller
- Masato Yasui
- Yuki Teramoto
- Takuro Goto
- Sabeeha Reshi
- Jennifer Hong
- Naixin Zhang
- Diya Pandey
- Priyanka Srivastava
- Alexandra Morell
- Hiroki Kawano
- Yuko Kawano
- Thomas Conley
- Deepak Sahasrabudhe
- Naohiro Yano
- ...
Cancers ; Volume: 15 ; Page: 3432
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Structural analysis and biological activities of C25-amino and C25-nitro vitamin D analogs
- Uxía Gómez-Bouzó
- Anna Belorusova
- Marcos L Rivadulla
- Hugo Santalla
- Lieve Verlinden
- Annemieke Verstuyf
- Maria J Ferronato
- Alejandro C Curino
- Maria M Facchinetti
- Yagamare Fall
- Generosa Gómez
- Natacha Rochel
Bioorganic Chemistry ; Volume: 136 ; Page: 106528
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