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Genetic diversity in the nematode egg-laying circuit modulates an intergenerational fitness trade-off

Regulation of natural transdifferentiation in Caenorhabditis elegans by chromatin remodellers, environmental cues and stress responses

From sequences to fitness and motions, protein language models to the rescue?

Mandatory registration only for external staff >> here<< (access badge) Recent advancements in protein language models (pLMs) show promise in…

Species-wide quantitative transcriptomes and proteomes reveal distinct genetic control of gene expression variation

Gene expression is crucial for translating genotypes into phenotypes, yet our understanding of transcriptome and proteome variation at the species…

Characterization of developmental senescence using a new reporter mouse model to identify genes common across senescence states

Molecular mechanism underlying CaMK1D-dependent function in AgRP neurons

Development of an anti-diabetic kidney disease drug by targeting transcriptional activity of carbohydrate responsive element binding protein (ChREBP)

More than 30% of diabetic patients will eventually develop diabetic kidney disease (DKD), characterized by the presence of elevated urinary albumin…

Mini-Symposium Plasticity and Cancer

Cellular senescence: a complex interplay between tumor suppression and embryonic signaling