Structural and functional basis of chromatin remodelling
Team Leader : Elisa BERGAMIN
Department : Functional genomics and cancer
Since its creation 30 years ago, the IGBMC has been a major player in cancer research. A pioneer in France in the study of nuclear receptors and their links with transcription, with certain receptors (estrogen, androgen, vitamin D3, vitamin A, etc.) having strong links with cancer, the institute's research teams and technological facilities together account for almost two-thirds of Cancéropôle Est's research strengths. The IGBMC also benefits from the support of numerous associations, such as the Ligue contre le cancer (several accredited teams), the Fondation ARC pour la recherche sur le cancer and Worldwide Research Cancer.
The IGBMC interacts with numerous professors at Strasbourg University Hospitals on translational projects involving sarcomas, pancreatic cancers, breast cancers, urological cancers, melanomas and gynecological cancers in particular. For all these types of cancer, medical researchers have completed their thesis at the IGBMC and continue their hospital activities with a research component at the IGBMC.
Some teams have focused their work on both rare and more common cancers:
The research carried out at the IGBMC touches on a number of cross-disciplinary subjects, and the knowledge generated concerns the biological mechanisms most often involved in cancer pathologies. For example, the institute is now at the cutting edge of high-performance research, being one of the first research centers in France to characterize the tumor cell ecosystem on a single-cell scale, with the spatio-temporal genomic study of tumors.
Team Leader : Elisa BERGAMIN
Department : Functional genomics and cancer
Team Leaders : Pierre CATTENOZ , Angela GIANGRANDE
Department : Functional genomics and cancer
Team Leader : Jean CAVARELLI
Department : Integrated structural biology
Team Leaders : Susan CHAN , Philippe KASTNER
Department : Functional genomics and cancer
Team Leader : Frederic COIN
Department : Functional genomics and cancer
Team Leader : Irwin DAVIDSON
Department : Functional genomics and cancer
Team Leader : Ali HAMICHE
Department : Functional genomics and cancer
Team Leader : Sophie JARRIAULT
Department : Development and stem cells
Team Leader : Bill KEYES
Department : Development and stem cells
Team Leader : Mei LI
Department : Functional genomics and cancer
Team Leader : Manuel MENDOZA
Department : Development and stem cells
Team Leader : Daniel METZGER
Department : Functional genomics and cancer
Team Leader : Bernardo REINA SAN MARTIN
Department : Development and stem cells
Team Leader : Christophe ROMIER
Department : Integrated structural biology
Team Leader : Patrick SCHULTZ
Department : Integrated structural biology
Team Leader : Bertrand SERAPHIN
Team Leader : Thomas SEXTON
Department : Functional genomics and cancer
Team Leader : Izabela SUMARA
Department : Development and stem cells
Team Leader : Catherine-Laure TOMASETTO
Department : Functional genomics and cancer
Team Leader : Gilles TRAVE
Department : Integrated structural biology
Team Leader : Stephane VINCENT
Department : Development and stem cells
Team Leader : Albert WEIXLBAUMER
Department : Integrated structural biology