Eukaryotic mRNA decay
Team Leader : Bertrand SERAPHIN
Department : Executive management
Bertrand SERAPHIN
Researcher
seraphin@igbmc.fr
Research team(s)
Research subgroup(s)
Publications
2025
Article in a journal
The CCR4–NOT complex: a multifaceted sensor of molecular signals instructing eukaryotic mRNA translation and stability
- Guillaume Caulier
- Joseph Siblini
- Lina Sène
- Fabienne Mauxion
- Bertrand Séraphin
Nucleic Acids Research ; Volume: 53
2023
Chapter of the book
An RNA-ligation-based RACE-PAT assay to monitor poly(A) tail length of mRNAs of interest
- Fabienne Mauxion
- Bertrand Séraphin
Methods in Molecular Biology ; Page: 113-123
Article in a journal
HELZ2: a new, interferon-regulated, human 3′-5′ exoribonuclease of the RNB family is expressed from a non-canonical initiation codon
- Eric Huntzinger
- Jordan Sinteff
- Bastien Morlet
- Bertrand Séraphin
Nucleic Acids Research
Pre-publication, Working Document
Multiple Myeloma associated DIS3 mutations drive AID-dependent IGH Translocations
- Tomasz Kuliński
- Olga Gewartowska
- Mélanie Mahé
- Karolina Kasztelan
- Janina Durys
- Anna Stroynowska-Czerwińska
- Marta Jedynak-Slyvka
- Ewelina Owczarek
- Debadeep Chaudhury
- Marcin Nowotny
- Aleksandra Pękowska
- Bertrand Séraphin
- Andrzej Dziembowski
Article in a journal
The human CNOT1-CNOT10-CNOT11 complex forms a structural platform for protein-protein interactions
- Fabienne Mauxion
- Jérôme Basquin
- Sevim Ozgur
- Marion Rame
- Jana Albrecht
- Ingmar Schäfer
- Bertrand Séraphin
- Elena Conti
Cell Reports ; Volume: 42 ; Page: 111902
2022
Article in a journal
The S. cerevisiae m6A-reader Pho92 promotes timely meiotic recombination by controlling key methylated transcripts
- Jérémy Scutenaire
- Damien Plassard
- Mélody Matelot
- Tommaso Villa
- Julie Zumsteg
- Domenico Libri
- Bertrand Séraphin
Nucleic Acids Research
2021
Article in a journal
A conserved motif in human BTG1 and BTG2 proteins mediates interaction with the poly(A) binding protein PABPC1 to stimulate mRNA deadenylation
- Hamza Amine
- Nina Ripin
- Sahil Sharma
- Georg Stoecklin
- Frédéric Allain
- Bertrand Séraphin
- Fabienne Mauxion
RNA Biology ; Page: 1-16
2020
Article in a journal
Pby1 is a direct partner of the Dcp2 decapping enzyme
- Clément Charenton
- Claudine Gaudon-Plesse
- Régis Back
- Nathalie Ulryck
- Loreline Cosson
- Bertrand Séraphin
- Marc Graille
Nucleic Acids Research ; Volume: 48
2019
Article in a journal
Mammalian Hbs1L deficiency causes congenital anomalies and developmental delay associated with Pelota depletion and 80S monosome accumulation
- Amy O'Connell
- Maxim Gerashchenko
- Marie-Françoise O'Donohue
- Samantha Rosen
- Eric Huntzinger
- Diane Gleeson
- Antonella Galli
- Edward Ryder
- Siqi Cao
- Quinn Murphy
- Shideh Kazerounian
- Sarah Morton
- Klaus Schmitz-Abe
- Vadim Gladyshev
- Pierre-Emmanuel Gleizes
- Bertrand Séraphin
- Pankaj Agrawal
PLoS Genetics ; Volume: 15 ; Page: e1007917
2017
Article in a journal
A unique surface on Pat1 C-terminal domain directly interacts with Dcp2 decapping enzyme and Xrn1 5′–3′ mRNA exonuclease in yeast
- Clément Charenton
- Claudine Gaudon-Plesse
- Zaineb Fourati
- Valério Taverniti
- Régis Back
- Olga Kolesnikova
- Bertrand Séraphin
- Marc Graille
Proceedings of the National Academy of Sciences of the United States of America ; Volume: 114 ; Page: E9493-E9501