Eukaryotic mRNA decay
Team Leader : Bertrand SERAPHIN
Department : Executive management
SUBGROUP LEADER
In eukaryotes, mRNA decay is intimately associated with translation. The latter process relies on specific marks to be efficient, namely the 5’ mRNA cap and the 3’ poly(A) tail. These characteristic modifications that delimits full mRNAs become ultimately the targets of the mRNA decay machinery. We are investigating how mRNA decay factors interact and/or interfere with the translation apparatus and how RNA modifications affect translation.
Chapter of the book
Methods in Molecular Biology ; Page: 113-123
Article in a journal
Nucleic Acids Research
Article in a journal
Cell Reports ; Volume: 42 ; Page: 111902
Article in a journal
Nucleic Acids Research
Article in a journal
RNA Biology ; Page: 1-16
Article in a journal
Nucleic Acids Research ; Volume: 48
Article in a journal
PLoS Genetics ; Volume: 15 ; Page: e1007917
Article in a journal
Proceedings of the National Academy of Sciences of the United States of America ; Volume: 114 ; Page: E9493-E9501
Article in a journal
RNA ; Volume: 23 ; Page: 968-981
Article in a journal
EMBO Reports ; Volume: 18 ; Page: 264-279