Pathophysiological role of nuclear receptor signalling
Team Leader : Daniel METZGER
Department : Functional genomics and cancer
Daniel METZGER
Researcher
metzger@igbmc.fr
Research team(s)
Research subgroup(s)
Publications
-
2024
-
LSD1 inhibition circumvents glucocorticoid-induced muscle wasting of male mice
- Qingshuang Cai
- Rajesh Sahu
- Vanessa Ueberschlag-Pitiot
- Sirine Souali-Crespo
- Céline Charvet
- Ilyes Silem
- Félicie Cottard
- Tao Ye
- Fatima Taleb
- Eric Metzger
- Roland Schuele
- Isabelle Billas
- Gilles Laverny
- Daniel Metzger
- Delphine Duteil
Nature Communications ; Volume: 15 ; Page: 3563
-
-
2023
-
Androgen receptor coordinates muscle metabolic and contractile functions
- Kamar Ghaibour
- Mélanie Schuh
- Sirine Souali‐crespo
- Céline Chambon
- Anouk Charlot
- Joe Rizk
- Daniela Rovito
- Anna‐isavella Rerra
- Qingshuang Cai
- Nadia Messaddeq
- Joffrey Zoll
- Delphine Duteil
- Daniel Metzger
Journal of Cachexia, Sarcopenia and Muscle ; Volume: 14 ; Page: 1707 - 1720
-
-
2022
-
Vitamin D Analogs Bearing C-20 Modifications Stabilize the Agonistic Conformation of Non-Responsive Vitamin D Receptor Variants
- Anna Belorusova
- Daniela Rovito
- Yassmine Chebaro
- Stefanie Doms
- Lieve Verlinden
- Annemieke Verstuyf
- Daniel Metzger
- Natacha Rochel
- Gilles Laverny
International Journal of Molecular Sciences ; Volume: 23 ; Page: 8445
-
Hypoxia-mediated stabilization of HIF1A in prostatic intraepithelial neoplasia promotes cell plasticity and malignant progression
- Mohamed A Abu El Maaty
- Julie Terzic
- Céline Keime
- Daniela Rovito
- Régis Lutzing
- Darya Yanushko
- Maxime Parisotto
- Elise Grelet
- Izzie Jacques Namer
- Véronique Lindner
- Gilles Laverny
- Daniel Metzger
Science Advances ; Volume: 8 ; Page: eabo2295
-
TRPC3 shapes the ER-mitochondria Ca2+ transfer characterizing tumour-promoting senescence
- Valerio Farfariello
- Dmitri Gordienko
- Lina Mesilmany
- Yasmine Touil
- Emmanuelle Germain
- Ingrid Fliniaux
- Emilie Desruelles
- Dimitra Gkika
- Morad Roudbaraki
- George Shapovalov
- Lucile Noyer
- Mathilde Lebas
- Laurent Allart
- Nathalie Zienthal-Gelus
- Oksana Iamshanova
- Franck Bonardi
- Martin Figeac
- William Laine
- Jerome Kluza
- Philippe Marchetti
- ...
Nature Communications ; Volume: 13 ; Page: 956
-
-
2021
-
Single-cell analyses unravel cell type–specific responses to a vitamin D analog in prostatic precancerous lesions
- Mohamed Abu El Maaty
- Elise Grelet
- Céline Keime
- Anna-Isavella Rerra
- Justine Gantzer
- Camille Emprou
- Julie Terzic
- Régis Lutzing
- Jean-Marc Bornert
- Gilles Laverny
- Daniel Metzger
Science Advances ; Volume: 7
-
Myod1 and GR coordinate myofiber-specific transcriptional enhancers
- Daniela Rovito
- Anna-Isavella Rerra
- Vanessa Ueberschlag-Pitiot
- Shilpy Joshi
- Nezih Karasu
- Vanessa Dacleu-Siewe
- Khalil Ben Rayana
- Kamar Ghaibour
- Maxime Parisotto
- Arnaud Ferry
- Scott A Jelinsky
- Gilles Laverny
- Bruno P Klaholz
- Tom Sexton
- Isabelle M L Billas
- Delphine Duteil
- Daniel Metzger
Nucleic Acids Research ; Volume: 49 ; Page: 4472 - 4492
-
Tyrosine hydroxylase conditional KO mice reveal peripheral tissue-dependent differences in dopamine biosynthetic pathways
- Katsuya Miyajima
- Chiaki Kawamoto
- Satoshi Hara
- Masayo Mori-Kojima
- Tamae Ohye
- Chiho Sumi-Ichinose
- Nae Saito
- Toshikuni Sasaoka
- Daniel Metzger
- Hiroshi Ichinose
Journal of Biological Chemistry ; Volume: 296 ; Page: 100544
-
-
2020
-
In vivo RyR1 reduction in muscle triggers a core-like myopathy
- Laurent Pelletier
- Anne Petiot
- Julie Brocard
- Benoit Giannesini
- Diane Giovannini
- Colline Sanchez
- Lauriane Travard
- Mathilde Chivet
- Mathilde Beaufils
- Candice Kutchukian
- David Bendahan
- Daniel Metzger
- Clara Franzini Armstrong
- Norma B Romero
- John Rendu
- Vincent Jacquemond
- Julien Fauré
- Isabelle Marty
Acta Neuropathologica Communications ; Volume: 8
-
Cytosolic sequestration of the vitamin D receptor as a therapeutic option for vitamin D-induced hypercalcemia
- Daniela Rovito
- Anna y Belorusova
- Sandra Chalhoub
- Anna-Isavella Rerra
- Elvire Guiot
- Arnaud Molin
- Agnès Linglart
- Natacha Rochel
- Gilles Laverny
- Daniel Metzger
Nature Communications ; Volume: 11 ; Page: 6249
-