Spatial organisation of the genome
Team Leader : Thomas SEXTON
Department : Functional genomics and cancer
Thomas SEXTON
Researcher
thomas.sexton@igbmc.fr
Research team(s)
Publications
2021
Age-related and disease locus-specific mechanisms contribute to early remodelling of chromatin structure in Huntington’s disease mice
- Rafael Alcalá-Vida
- Jonathan Seguin
- Caroline Lotz
- Anne Molitor
- Ibai Irastorza-Azcarate
- Ali Awada
- Nezih Karasu
- Aurélie Bombardier
- Brigitte Cosquer
- Jose Luis Gomez Skarmeta
- Jean-Christophe Cassel
- Anne-Laurence Boutillier
- Thomas Sexton
- Karine Merienne
Nature Communications ; Volume: 12 ; Page: 364
Precise measurements of chromatin diffusion dynamics by modeling using Gaussian processes
- Guilherme Oliveira
- Attila Oravecz
- Dominique Kobi
- Manon Maroquenne
- Kerstin Bystricky
- Thomas Sexton
- Nacho Molina
Nature Communications ; Volume: 12 ; Page: 6184
Precise measurements of chromatin diffusion dynamics by modeling using Gaussian processes
- Guilherme Monteiro Oliveira
- Attila Oravec
- Dominique Kobi
- Manon Maroquenne
- Kerstin Bystricky
- Thomas Sexton
- Nacho Molina
Nature Communications ; Volume: 12
4C-Seq: Interrogating Chromatin Looping with Circular Chromosome Conformation Capture
- Nezih Karasu
- Thomas Sexton
Methods in molecular biology (Clifton, N.J.) ; Volume: 2157 ; Page: 19-34
Assessment of 3D Interactions Between Promoters and Distal Regulatory Elements with Promoter Capture Hi-C (PCHi-C)
- Nezih Karasu
- Thomas Sexton
Methods in molecular biology (Clifton, N.J.) ; Volume: 2351 ; Page: 229-248
2020
Alternative Enhancer Usage and Targeted Polycomb Marking Hallmark Promoter Choice during T Cell Differentiation
- Muhammad Ahmad Maqbool
- Léo Pioger
- Amal Zine El Aabidine
- Nezih Karasu
- Anne Marie Molitor
- Lan T M Dao
- Guillaume Charbonnier
- Francois van Laethem
- Romain Fenouil
- Frederic Koch
- Georges Lacaud
- Ivo Gut
- Marta Gut
- Sebastian Amigorena
- Olivier Joffre
- Thomas Sexton
- Salvatore Spicuglia
- Jean-Christophe Andrau
Cell Reports ; Volume: 32
2017
Single-cell absolute contact probability detection reveals chromosomes are organized by multiple low-frequency yet specific interactions
- Diego Cattoni
- Andrés M Cardozo Gizzi
- Mariya Georgieva
- Marco Di Stefano
- Alessandro Valeri
- Delphine Chamousset
- Christophe Houbron
- Stephanie Déjardin
- Jean-Bernard Fiche
- Inma González
- Jia-Ming Chang
- Thomas Sexton
- Marc A Marti-Renom
- Frederic Bantignies
- Giacomo Cavalli
- Marcelo Nollmann
Nature Communications ; Volume: 8 ; Page: 1753
Detecting Spatial Chromatin Organization by Chromosome Conformation Capture II: Genome-Wide Profiling by Hi-C
- Matteo Viettri Rudan
- Suzana Hadjur
- Thomas Sexton
Methods in Molecular Biology ; Volume: 1589 ; Page: 47-74