Genome expression and repair
Team Leader : Frédéric COIN
Department : Functional genomics and cancer
Frédéric COIN
Research team(s)
Publications
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2025
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Pan-inhibition of super-enhancer-driven oncogenic transcription by next-generation synthetic ecteinascidins yields potent anti-cancer activity
- Max Cigrang
- Julian Obid
- Maguelone Nogaret
- Leane Seno
- Tao Ye
- Guillaume Davidson
- Philippe Catez
- Pietro Berico
- Clara Capelli
- Clara Marechal
- Amélie Zachayus
- Clémence Elly
- Marie Jose Guillen Navarro
- Marta Martínez Diez
- Gema Santamaria Nunez
- Tsai-Kun Li
- Emmanuel Compe
- Pablo Avilés
- Irwin Davidson
- Jean-Marc Egly
- ...
Nature Communications ; Volume: 16 ; Page: 512
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2023
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Active mRNA degradation by EXD2 nuclease elicits recovery of transcription after genotoxic stress
- Jérémy Sandoz
- Max Cigrang
- Amélie Zachayus
- Philippe Catez
- Lise-Marie Donnio
- Clèmence Elly
- Jadwiga Nieminuszczy
- Pietro Berico
- Cathy Braun
- Sergey Alekseev
- Jean-Marc Egly
- Wojciech Niedzwiedz
- Giuseppina Giglia-Mari
- Emmanuel Compe
- Frédéric Coin
Nature Communications ; Volume: 14 ; Page: 341
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Super-enhancer-driven expression of BAHCC1 promotes melanoma cell proliferation and genome stability
- Pietro Berico
- Maguelone Nogaret
- Max Cigrang
- Antonin Lallement
- Fatemeh Vand-Rajabpour
- Amanda Flores-Yanke
- Giovanni Gambi
- Guillaume Davidson
- Leane Seno
- Jolian Obid
- Bujamin H. Vokshi
- Stéphanie Le Gras
- Gabrielle Mengus
- Tao Ye
- Carlos Fernandez Cordero
- Mélanie Dalmasso
- Emmanuel Compe
- Corine Bertolotto
- Eva Hernando
- Irwin Davidson
- ...
Cell Reports ; Volume: 42 ; Page: 113363
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2022
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Phosphorylation of XPD drives its mitotic role independently of its DNA repair and transcription functions
- Emmanuel Compe
- Evanthia Pangou
- Nicolas Le May
- Clémence Elly
- Cathy Braun
- Ji-Hyun Hwang
- Frédéric Coin
- Izabela Sumara
- Kwang-Wook Choi
- Jean-Marc Egly
Science Advances ; Volume: 8
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Phosphorylation of XPD drives its mitotic role independently of its DNA repair and transcription functions
- Emmanuel Compe
- Evanthia Pangou
- Nicolas Le May
- Clémence Elly
- Cathy Braun
- Ji-Hyun Hwang
- Frédéric Coin
- Izabela Sumara
- Kwang-Wook Choi
- Jean-Marc Egly
Science Advances ; Volume: 8
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Promoters of ASCL1‐ and NEUROD1‐dependent genes are specific targets of lurbinectedin in SCLC cells
- Federico Costanzo
- Marta Martínez Diez
- Gema Santamaría Nuñez
- Juan Ignacio Díaz-Hernandéz
- Carlos Mario Genes Robles
- Javier Díez Pérez
- Emmanuel Compe
- Romeo Ricci
- Tsai‐kun Li
- Frédéric Coin
- Juan Fernando Martínez Leal
- Eva Maria Garrido-Martin
- Jean Marc Egly
EMBO Molecular Medicine ; Volume: 14
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2021
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CDK7 and MITF repress a transcription program involved in survival and drug tolerance in melanoma
- Pietro Berico
- Max Cigrang
- Guillaume Davidson
- Cathy Braun
- Jeremy Sandoz
- Stephanie Legras
- Bujamin Hektor Vokshi
- Nevena Slovic
- François Peyresaubes
- Carlos Mario Gene Robles
- Jean‐marc Egly
- Emmanuel Compe
- Irwin Davidson
- Frédéric Coin
EMBO Reports ; Volume: 22 ; Page: e51683
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The Long Road to Understanding RNAPII Transcription Initiation and Related Syndromes
- Frédéric Coin
- Emmanuel Compe
- Jean-Marc Egly
Annual Review of Biochemistry ; Volume: 90 ; Page: 193-219
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2020
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Defective transcription of ATF3 responsive genes, a marker for Cockayne Syndrome
- Alexey Epanchintsev
- Marc-Alexander Rauschendorf
- Federico Costanzo
- Nadege Calmels
- Cathy Obringer
- Alain Sarasin
- Frédéric Coin
- Vincent Laugel
- Jean‐marc Egly
Scientific Reports ; Volume: 10 ; Page: 1105
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Defective transcription of ATF3 responsive genes, a marker for Cockayne Syndrome
- Alexey Epanchintsev
- Marc-Alexander Rauschendorf
- Federico Costanzo
- Nadège Calmels
- Cathy Obringer
- Alain Sarasin
- Frédéric Coin
- Vincent Laugel
- Jean-Marc Egly
Scientific Reports ; Volume: 10 ; Page: 1105
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