Régulation de la topologie de l'ADN
Chefs d'équipe : Valerie LAMOUR , Marc RUFF
Département : Biologie structurale intégrative
Découverte de médicaments contre les bactéries nosocomiales
Découverte de médicaments contre les bactéries nosocomiales
RESPONSABLE DE SOUS-GROUPE
Équipes
Membres
Chercheur(euse)s
Publications
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2018
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Post-translational modifications in DNA topoisomerase 2α highlight the role of a eukaryote-specific residue in the ATPase domain
- Claire Bedez
- Christophe Lotz
- Claire Batisse
- Arnaud Vanden Broeck
- Roland Stote
- Eduardo Howard
- Karine Pradeau Aubreton
- Marc Ruff
- Valerie Lamour
Scientific Reports ; Volume: 8
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Genetic Flexibility of the NKNK Motif in HIV-1 Integrases Allows Its Involvement in Multiple Functions During Infection
- Marine Kanja
- Pierre Cappy
- Guillermo Blanco-Rodriguez
- Nicolas Levy
- Sylvie Schmidt
- Romain Gasser
- Paola Rossolillo
- Christiane Moog
- M. Ruff
- Francesca Di Nunzio
- Matteo Negroni
- Daniela Lener
Synthetic Biology eJournal
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Structure-function analyses unravel distinct effects of allosteric inhibitors of HIV-1 integrase on viral maturation and integration
- Damien Bonnard
- Erwann Le Rouzic
- Sylvia Eiler
- Céline Amadori
- Igor Orlov
- Jean-Michel Bruneau
- Julie Brias
- Julien Barbion
- Francis Chevreuil
- Daniele Spehner
- Sophie Chasset
- Benoit Ledoussal
- François Moreau
- Ali Saib
- Bruno P. Klaholz
- Stéphane Emiliani
- Marc Ruff
- Alessia Zamborlini
- Richard Benarous
Journal of Biological Chemistry ; Volume: 293 ; Page: 6172-6186
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Unstable Protein Purification Through the Formation of Stable Complexes
- Sylvia Eiler
- Nicolas Lévy
- Benoit Maillot
- Julien Batisse
- Karine Pradeau Aubreton
- Oyindamola Oladosu
- Marc Ruff
Methods in Molecular Biology ; Page: 315-328
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Toward High Resolution Structures of the HIV-1 In/LEDGF/DNA Complex
- Julien Batisse
- Eduardo Bruch
- Nicolas Lévy
- Benoit Maillot
- Sylvia Eiler
- Oyindamola Oladosu
- Marc Ruff
Biophysical Journal ; Volume: 114 ; Page: 218a
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2017
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The HIV-1 integrase-LEDGF allosteric inhibitor MUT-A: resistance profile, impairment of virus maturation and infectivity but without influence on RNA packaging or virus immunoreactivity
- Céline Amadori
- Yme Ubeles van Der Velden
- Damien Bonnard
- Igor Orlov
- Nikki van Bel
- Erwann Le Rouzic
- Laia Miralles
- Julie Brias
- Francis Chevreuil
- Daniele Spehner
- Sophie Chasset
- Benoit Ledoussal
- Luzia Mayr
- François Moreau
- Felipe García
- José Gatell
- Alessia Zamborlini
- Stéphane Emiliani
- Marc Ruff
- Bruno P. Klaholz
- ...
Retrovirology ; Volume: 14 ; Page: 50
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Modulation of chromatin structure by the FACT histone chaperone complex regulates HIV-1 integration
- Julien Matysiak
- Paul Lesbats
- Eric Mauro
- Delphine Lapaillerie
- Jean-William Dupuy
- Angelica P. Lopez
- Mohamed Salah Benleulmi
- Christina Calmels
- Marie-Line Andreola
- Marc Ruff
- Manuel Llano
- Olivier Delelis
- Marc Lavigne
- Vincent Parissi
Retrovirology ; Volume: 14 ; Page: 39
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Dynamics of Methylated Cytosine Flipping by UHRF1
- Christian Bronner
- Vasyl Kilin
- Krishna Gavvala
- Nicolas Barthes
- Benoît Michel
- Dongwon Shin
- Christian Boudier
- Olivier Mauffret
- Valeriy Yashchuk
- Marc Mousli
- Marc Ruff
- Florence Granger
- Sylvia Eiler
- Yitzhak Tor
- Alain Burger
- Yves Mély
Journal of the American Chemical Society ; Volume: 139 ; Page: 2520-2528
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The HIV-1 Pre-Integration Complexes: Structures, Functions and Dynamics
- Nicolas Levy
- Karine Pradeau-Aubreton
- Sylvia Eiler
- Julien Batisse
- Oyindamola Oladosu
- Benoit Maillot
- Marc Ruff
Biophysical Journal ; Volume: 112 ; Page: 30a
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Modulation of the functional association between the HIV-1 intasome and the nucleosome by histone amino-terminal tails
- Mohamed S Benleulmi
- Julien Matysiak
- Xavier Robert
- Csaba Miskey
- Eric Mauro
- Delphine Lapaillerie
- Paul Lesbats
- Stéphane Chaignepain
- Daniel R Henriquez
- Christina Calmels
- Oyindamola Oladosu
- Eloïse Thierry
- Oscar Leon
- Marc Lavigne
- Marie-Line Andreola
- Olivier Delelis
- Zoltán Ivics
- Marc Ruff
- Patrice Gouet
- Vincent Parissi
Retrovirology ; Volume: 14 ; Page: 54
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