Structure-fonction des complexes impliqués dans le cycle de réplication du VIH, conception de médicaments

Publications

• 2003

  • The dual role of CHAPS in the crystallization of stromelysin-3 catalytic domain

    • Anne-Laure Gall
    • Marc Ruff
    • Dino Moras

    Acta Crystallographica Section D: Biological Crystallography ; Volume: 59 ; Page: 603-606

    HAL DOI

• 2001

  • Crystal structure of a mutant hERalpha ligand-binding domain reveals key structural features for the mechanism of partial agonism

    • Monique Gangloff
    • Marc Ruff
    • Sylvia Eiler
    • Sylvie Duclaud
    • Jean-Marie Wurtz
    • Dino Moras

    Journal of Biological Chemistry ; Volume: 276 ; Page: 15059-15065

    HAL DOI

  • Crystal structure of the stromelysin-3 (MMP-11) catalytic domain complexed with a phosphinic inhibitor mimicking the transition-state11

    • Anne-Laure Gall
    • Marc Ruff
    • Rama Kannan
    • Philippe Cuniasse
    • Athanasios Yiotakis
    • Vincent Dive
    • Marie-Christine Rio
    • Paul Basset
    • Dino Moras

    Journal of Molecular Biology ; Volume: 307 ; Page: 577-586

    HAL DOI

• 1998

  • Human TAFII28 and TAFII18 Interact through a Histone Fold Encoded by Atypical Evolutionary Conserved Motifs Also Found in the SPT3 Family

    • Catherine Birck
    • Olivier Poch
    • Christophe Romier
    • Marc Ruff
    • Gabrielle Mengus
    • Anne-Claire Lavigne
    • Irwin Davidson
    • Dino Moras

    Cell ; Volume: 94 ; Page: 239-249

    HAL DOI

• 1996

  • Crystallization and preliminary X-ray analysis of Escherichia coli methionyl–tRNA fMet formyltransferase

    • Emmanuelle Schmitt
    • Yves Mechulam
    • Marc Ruff
    • André Mitschler
    • Dino Moras
    • Sylvain Blanquet

    Proteins - Structure, Function and Bioinformatics ; Volume: 25 ; Page: 139-141

    HAL DOI

  • Crystallization of Escherichia coli aspartyl-tRNA synthetase in its free state and in a complex with yeast tRNAAsp

    • M. Boeglin
    • A. Dock-Bregeon
    • G. Eriani
    • J. Gangloff
    • M. Ruff
    • A. Poterszman
    • A. Mitschler
    • J. Thierry
    • D. Moras

    Acta crystallographica Section D : Structural biology [1993-...] ; Volume: 52 ; Page: 211-214

    HAL DOI

• 1995

  • Crystal structure of the ligand-binding domain of the human nuclear receptor RXR-alpha

    • William Bourguet
    • Marc Ruff
    • Pierre Chambon
    • Hinrich Gronemeyer
    • Dino Moras

    Nature ; Volume: 375 ; Page: 377-382

    HAL DOI

• 1992

  • Class II aminoacyl-tRNA synthetases seen through the crystal structure of the complex between yeast tRNAAsp aspartyl-tRNA synthetase

    • Jean Cavarelli
    • B. Rees
    • Marc Ruff
    • Arnaud Poterszman
    • J. C. Thierry
    • Dino Moras

    Structural Tools for the Analysis of Protein-nucleic Acid Complexes ; Page: 287-298

    HAL

  • The crystal structure of yeast tRNAAsp complexed with its cognate synthetase; functional relevance to class II aaRSS

    • Marc Ruff
    • Marcel Boeglin
    • S. Krishnaswamy
    • André Mitschler
    • Alberto Podjarny
    • Arnaud Poterszman
    • B. Rees
    • Dino Moras

    Structure and Function. Vol. 2: Proteins ; Page: 159-168

    HAL