Rôles physiopathologiques des voies de signalisation des récepteurs nucléaires
Chef d'équipe : Daniel METZGER
Département : Génomique fonctionnelle et cancer
Daniel METZGER
Chercheur
metzger@igbmc.fr
Équipe(s)
Sous-groupe(s)
Publications
2007
Article dans une revue
Estrogen prevents bone loss via estrogen receptor alpha and induction of Fas ligand in osteoclasts.
- Takashi Nakamura
- Yuuki Imai
- Takahiro Matsumoto
- Shingo Sato
- Kazusane Takeuchi
- Katsuhide Igarashi
- Yoshiaki Azuma
- Andree Krust
- Yoko Yamamoto
- Hiroshi Nishina
- Shu Takeda
- Hiroshi Takayanagi
- Daniel Metzger
- Jun Kanno
- Kunio Takaoka
- T John Martin
- Pierre Chambon
- Shigeaki Kato
Cell ; Volume: 130 ; Page: 811-23
Article dans une revue
LRH-1-mediated glucocorticoid synthesis in enterocytes protects against inflammatory bowel disease.
- Agnès Coste
- Laurent Dubuquoy
- Romain Barnouin
- Jean-Sébastien Annicotte
- Benjamin Magnier
- Mario Notti
- Nadia Corazza
- Maria Cristina Antal
- Daniel Metzger
- Pierre Desreumaux
- Thomas Brunner
- Johan Auwerx
- Kristina Schoonjans
Proceedings of the National Academy of Sciences of the United States of America ; Volume: 104 ; Page: 13098-103
Article dans une revue
The TFIID subunit TAF4 regulates keratinocyte proliferation and has cell-autonomous and non-cell-autonomous tumour suppressor activity in mouse epidermis.
- Anas Fadloun
- Dominique Kobi
- Jean-Christophe Pointud
- Arup Kumar Indra
- Marius Teletin
- Christine Bole-Feysot
- Barbara Testoni
- Roberto Mantovani
- Daniel Metzger
- Gabrielle Mengus
- Irwin Davidson
Development (Cambridge, England) ; Volume: 134 ; Page: 2947-58
Article dans une revue
IL-13 induces expression of CD36 in human monocytes through PPARgamma activation.
- Antoine Berry
- Patricia Balard
- Agnès Coste
- David Olagnier
- Céline Lagane
- Hélène Authier
- Françoise Benoit-Vical
- Jean-Claude Lepert
- Jean-Paul Séguéla
- Jean-François Magnaval
- Pierre Chambon
- Daniel Metzger
- Béatrice Desvergne
- Walter Wahli
- Johan Auwerx
- Bernard Pipy
European Journal of Immunology ; Volume: 37 ; Page: 1642-52
Article dans une revue
Malignant transformation of DMBA/TPA-induced papillomas and nevi in the skin of mice selectively lacking retinoid-X-receptor alpha in epidermal keratinocytes.
- Arup Kumar Indra
- Eduardo Castaneda
- Maria Cristina Antal
- Ming Jiang
- Nadia Messaddeq
- Xiangjun Meng
- Christiane V Loehr
- Patricio Gariglio
- Shigeaki Kato
- Walter Wahli
- Béatrice Desvergne
- Daniel Metzger
- Pierre Chambon
Journal of Investigative Dermatology ; Volume: 127 ; Page: 1250-60
Article dans une revue
Inducible Cre/loxP recombination in the mouse proximal tubule.
- Bernd Dworniczak
- Boris Skryabin
- Joëlle Tchinda
- Silke Heuck
- Franz-Josef Seesing
- Daniel Metzger
- Pierre Chambon
- Jürgen Horst
- Petra Pennekamp
Nephron Experimental Nephrology ; Volume: 106 ; Page: e11-20
Chapitre d’ouvrage
Contribution of targeted conditional somatic mutagenesis to deciphering retinoid X receptor functions and to generating mouse models of human diseases.
- Daniel Metzger
- Pierre Chambon
Handbook of Experimental Pharmacology ; Page: 511-524
2006
Article dans une revue
PGC1alpha expression is controlled in skeletal muscles by PPARbeta, whose ablation results in fiber-type switching, obesity, and type 2 diabetes.
- Michael Schuler
- Faisal Ali
- Céline Chambon
- Delphine Duteil
- Jean-Marc Bornert
- Aubry Tardivel
- Béatrice Desvergne
- Walter Wahli
- Pierre Chambon
- Daniel Metzger
Cell Metabolism ; Volume: 4 ; Page: 407-14
Article dans une revue
LPS-induced TNF-alpha factor (LITAF)-deficient mice express reduced LPS-induced cytokine: Evidence for LITAF-dependent LPS signaling pathways.
- Xiaoren Tang
- Daniel Metzger
- Susan Leeman
- Salomon Amar
Proceedings of the National Academy of Sciences of the United States of America ; Volume: 103 ; Page: 13777-82
Article dans une revue
Topical vitamin D3 and low-calcemic analogs induce thymic stromal lymphopoietin in mouse keratinocytes and trigger an atopic dermatitis.
- Mei Li
- Pierre Hener
- Zhikun Zhang
- Shigeaki Kato
- Daniel Metzger
- Pierre Chambon
Proceedings of the National Academy of Sciences of the United States of America ; Volume: 103 ; Page: 11736-41