Expression et réparation du génome
Chef d'équipe : Frederic COIN
Département : Génomique fonctionnelle et cancer
Frederic COIN
Équipe(s)
Publications
2017
Transcription without XPB Establishes a Unified Helicase-Independent Mechanism of Promoter Opening in Eukaryotic Gene Expression
- Sergey Alekseev
- Zita Nagy
- Jérémy Sandoz
- Amélie Weiss
- Jean-Marc Egly
- Nicolas Le May
- Frédéric Coin
Molecular Cell ; Volume: 65 ; Page: 504-514.e4
2016
Lurbinectedin Specifically Triggers the Degradation of Phosphorylated RNA Polymerase II and the Formation of DNA Breaks in Cancer Cells
- Gema Santamaría Nuñez
- Carlos Mario Genes Robles
- Christophe Giraudon
- Juan Fernando Martínez-Leal
- Emmanuel Compe
- Frédéric Coin
- Pablo Aviles
- Carlos María Galmarini
- Jean-Marc Egly
Molecular Cancer Therapeutics ; Volume: 15 ; Page: 2399-2412
2015
Revisiting the Function of CDK7 in Transcription by Virtue of a Recently Described TFIIH Kinase Inhibitor
- Frédéric Coin
- Jean-Marc Egly
Molecular Cell ; Volume: 59 ; Page: 513-514
Orchestral maneuvers at the damaged sites in nucleotide excision repair
- Sergey Alekseev
- Frédéric Coin
Cellular and Molecular Life Sciences ; Volume: 72 ; Page: 2177-2186
TFIIH Subunit Alterations Causing Xeroderma Pigmentosum and Trichothiodystrophy Specifically Disturb Several Steps during Transcription
- Frédéric Coin
- Amita Singh
- Emanuel Compe
- Nicolas Le may
- Jean-Marc Egly
American Journal of Human Genetics ; Volume: 96 ; Page: 194-207
2014
ZFC3H1, a Zinc Finger Protein, Modulates IL-8 Transcription by Binding with Celastramycin A, a Potential Immune Suppressor
- Takeshi Tomita
- Katsuaki Ieguchi
- Frédéric Coin
- Yasuhiro Kato
- Haruhisa Kikuchi
- Yoshiteru Oshima
- Shoichiro Kurata
- Yoshiro Maru
PLoS ONE ; Volume: 9 ; Page: e108957
Sequential and ordered assembly of a large DNA repair complex on undamaged chromatin
- Salim Ziani
- Zita Nagy
- Sergey Alekseev
- Evi Soutoglou
- Jean-Marc Egly
- Frédéric Coin
Journal of Cell Biology ; Volume: 206 ; Page: 589-598
A Small Molecule Screen Identifies an Inhibitor of DNA Repair Inducing the Degradation of TFIIH and the Chemosensitization of Tumor Cells to Platinum
- Sergey Alekseev
- Mériam Ayadi
- Laurent Brino
- Jean-Marc Egly
- Annette k. Larsen
- Frédéric Coin
Chemistry and Biology ; Volume: 21 ; Page: 398-407
2013
ELL, a novel TFIIH partner, is involved in transcription restart after DNA repair
- S. Mourgues
- V. Gautier
- A. Lagarou
- C. Bordier
- A. Mourcet
- J. Slingerland
- L. Kaddoum
- Frédéric Coin
- W. Vermeulen
- A. Gonzales de Peredo
- B. Monsarrat
- P.-O. Mari
- G. Giglia-Mari
Proceedings of the National Academy of Sciences of the United States of America ; Volume: 110 ; Page: 17927-17932
Histone Methyltransferase DOT1L Drives Recovery of Gene Expression after a Genotoxic Attack
- Valentyn Oksenych
- Alexander Zhovmer
- Salim Ziani
- Pierre-Olivier Mari
- Jitka Eberova
- Tiziana Nardo
- Miria Stefanini
- Giuseppina Giglia-Mari
- Jean-Marc Egly
- Frédéric Coin
PLoS Genetics ; Volume: 9 ; Page: e1003611