Régulation de l’expression génique et cancer
Chef d'équipe : Irwin DAVIDSON
Département : Génomique fonctionnelle et cancer
Irwin DAVIDSON
Chercheur
irwin@igbmc.fr
Équipe(s)
Publications
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2025
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Pan-inhibition of super-enhancer-driven oncogenic transcription by next-generation synthetic ecteinascidins yields potent anti-cancer activity
- Max Cigrang
- Julian Obid
- Maguelone Nogaret
- Léane Seno
- Tao Ye
- Guillaume Davidson
- Philippe Catez
- Pietro Berico
- Clara Capelli
- Clara Marechal
- Amélie Zachayus
- Clémence Elly
- Marie Jose Guillen Navarro
- Marta Martinez Diez
- Gema Santamaria Nunez
- Tsai-Kun Li
- Emmanuel Compe
- Pablo Avilés
- Irwin Davidson
- Jean-Marc Egly
- ...
Nature Communications ; Volume: 16 ; Page: 512
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2024
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Changes in AXL and/or MITF melanoma subpopulations in patients receiving immunotherapy
- M. Willemsen
- J. Bulgarelli
- S.K. Chauhan
- R.R. Lereim
- D. Angeli
- G. Grisendi
- G. Krebbers
- I. Davidson
- J.A. Kyte
- M. Guidoboni
- Rosalie M Luiten
- W.J. Bakker
Immuno-Oncology and Technology ; Volume: 24 ; Page: 101009
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An atlas of the human liver diurnal transcriptome and its perturbation by hepatitis C virus infection.
- Atish Mukherji
- Frank Juehling
- Yogy Simanjuntak
- Emilie Crouchet
- Fabio del Zompo
- Yuji Teraoka
- Alexandre Haller
- Philippe Baltzinger
- Soumith Paritala
- Fahmida Rasha
- Naoto Fujiwara
- Cloé Gadenne
- Nevena Slovic
- Marine Oudot
- Sarah C. Durand
- Clara Ponsolles
- Catherine Schuster
- Xiaodong Zhuang
- Jacinta Holmes
- Ming-Lun Yeh
- ...
Nature Communications ; Volume: 15 ; Page: 7486
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2023
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Mesenchymal-like Tumor Cells and Myofibroblastic Cancer-Associated Fibroblasts Are Associated with Progression and Immunotherapy Response of Clear Cell Renal Cell Carcinoma
- Guillaume Davidson
- Alexandra Helleux
- Yann Vano
- Veronique Lindner
- Antonin Fattori
- Marie Cerciat
- Reza T. Elaidi
- Virginie Verkarre
- Cheng-Ming Sun
- Christine Chevreau
- Mostefa Bennamoun
- Hervé Lang
- Thibault Tricard
- Wolf H. Fridman
- Catherine Sautes-Fridman
- Xiaoping Su
- Damien Plassard
- Céline Keime
- Christelle Thibault-Carpentier
- Philippe Barthelemy
- ...
Cancer Research ; Volume: 83 ; Page: 2952-2969
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SMARCB1 regulates a TFCP2L1-MYC transcriptional switch promoting renal medullary carcinoma transformation and ferroptosis resistance
- Bujamin Vokshi
- Guillaume Davidson
- Nassim Tawanaie Pour Sedehi
- Alexandra Helleux
- Marc Rippinger
- Alexandre Haller
- Justine Gantzer
- Jonathan Thouvenin
- Philippe Baltzinger
- Rachida Bouarich
- Valeria Manriquez
- Sakina Zaidi
- Priya Rao
- Pavlos Msaouel
- Xiaoping Su
- Hervé Lang
- Thibault Tricard
- Véronique Lindner
- Didier Surdez
- Jean-Emmanuel Kurtz
- ...
Nature Communications ; Volume: 14 ; Page: 3034
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Epigenomic mapping identifies an enhancer repertoire that regulates cell identity in bladder cancer through distinct transcription factor networks
- Hélène Neyret-Kahn
- Jacqueline Fontugne
- Xiang Yu Meng
- Clarice Groeneveld
- Luc Cabel
- Tao Ye
- Elodie Guyon
- Clémentine Krucker
- Florent Dufour
- Elodie Chapeaublanc
- Audrey Rapinat
- Daniel Jeffery
- Laura Tanguy
- Victoria Dixon
- Yann Neuzillet
- Thierry Lebret
- David Gentien
- Irwin Davidson
- Yves Allory
- Isabelle Bernard-Pierrot
- ...
Oncogene ; Volume: 42 ; Page: 1524-1542
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An Enhancer Demethylator Phenotype Converged to Immune Dysfunction and Resistance to Immune Checkpoint Inhibitors in Clear-Cell Renal Cell Carcinomas
- Xiaofan Lu
- Yann Vano
- Alexandra Helleux
- Xiaoping Su
- Veronique Lindner
- Guillaume Davidson
- Roger Mouawad
- Jean-Philippe Spano
- Morgan Rouprêt
- Reza Elaidi
- Eva Compérat
- Virginie Verkarre
- Chengming Sun
- Christine Chevreau
- Mostefa Bennamoun
- Hervé Lang
- Thibault Tricard
- Wenxuan Cheng
- Li Xu
- Irwin Davidson
- ...
Clinical Cancer Research ; Volume: 29 ; Page: 1279-1291
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Phosphorylation of BRN2 Modulates Its Interaction with the Pax3 Promoter To Control Melanocyte Migration and Proliferation
- Irina Berlin
- Laurence Denat
- Anne-Lise Steunou
- Isabel Puig
- Delphine Champeval
- Sophie Colombo
- Karen Roberts
- Elise Bonvin
- Yveline Bourgeois
- Irwin Davidson
- Veronique Delmas
- Laurence Nieto
- Colin Goding
- Lionel Larue
Molecular and Cellular Biology ; Volume: 32 ; Page: 1237-1247
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Treatment of HCC with claudin-1-specific antibodies suppresses carcinogenic signaling and reprograms the tumor microenvironment
- Natascha Roehlen
- Marion Muller
- Zeina Nehme
- Emilie Crouchet
- Frank Jühling
- Fabio del Zompo
- Sara Cherradi
- François Ht Duong
- Nuno Almeida
- Antonio Saviano
- Mirian Fernández-Vaquero
- Tobias Riedl
- Houssein El Saghire
- Sarah C. Durand
- Clara Ponsolles
- Marine Oudot
- Romain Martin
- Nicolas Brignon
- Emanuele Felli
- Patrick Pessaux
- ...
Journal of Hepatology ; Volume: 78 ; Page: 343-355
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General transcription factor TAF4 antagonizes epigenetic silencing by Polycomb to maintain intestine stem cell functions.
- Susanna Säisä-Borreill
- Guillaume Davidson
- Thomas Kleiber
- Andréa Thevenot
- Elisabeth Martin
- Stanislas Mondot
- Hervé M. Blottiere
- Alexandra Helleux
- Gabrielle Mengus
- Michelina Plateroti
- Isabelle Duluc
- Irwin Davidson
- Jean-Noël Freund
Cell death and differentiation
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