Bases Moléculaires de la Régulation de la Chromatine et de la Transcription
Chef d'équipe : Christophe ROMIER
Département : Biologie structurale intégrative
Christophe ROMIER
Chercheur
romier@igbmc.fr
Équipe(s)
Publications
2016
Molecular basis and specificity of H2A.Z–H2B recognition and deposition by the histone chaperone YL1
- Chrysa Latrick
- Martin Marek
- Khalid Ouararhni
- Christophe Papin
- Isabelle Stoll
- Maria Ignatyeva
- Arnaud Obri
- Eric Ennifar
- Stefan Dimitrov
- Christophe Romier
- Ali Hamiche
Nature Structural and Molecular Biology ; Volume: 23 ; Page: 309-316
Synthesis and Biological Investigation of Oxazole Hydroxamates as Highly Selective Histone Deacetylase 6 (HDAC6) Inhibitors
- J. Senger
- J. Melesina
- Martin Marek
- Christophe Romier
- I. Oehme
- O. Witt
- W. Sippl
- M. Jung
Journal of Medicinal Chemistry ; Volume: 59 ; Page: 1545-55
Large-Scale Overproduction and Purification of Recombinant Histone Deacetylase 8 (HDAC8) from the Human-Pathogenic Flatworm Schistosoma mansoni
- Martin Marek
- Tajith Baba Shaik
- Sylvie Duclaud
- R. J. Pierce
- Christophe Romier
Methods in Molecular Biology ; Volume: 1436 ; Page: 109-18
2015
Characterization and Production of Protein Complexes by Co-expression in Escherichia coli
- Matthias Haffke
- Martin Marek
- Martin Pelosse
- Marie-Laure Diebold
- Uwe Schlattner
- Imre Berger
- Christophe Romier
Methods in Molecular Biology ; Volume: 1261 ; Page: 63-89
Schistosome sirtuins as drug targets
- Julien Lancelot
- Alejandro Cabezas Cruz
- Stéphanie Caby
- Martin Marek
- Johan Schultz
- Christophe Romier
- Wolfgang Sippl
- Manfred Jung
- Raymond J Pierce
Future Medicinal Chemistry ; Volume: 7 ; Page: 765-782
2014
Characterization of the interaction between protein Snu13p/15.5K and the Rsa1p/NUFIP factor and demonstration of its functional importance for snoRNP assembly
- Benjamin Rothé
- Régis Back
- Marc Quinternet
- Jonathan Bizarro
- Marie-Cécile Robert
- Magali Blaud
- Christophe Romier
- Xavier Manival
- Bruno Charpentier
- Edouard Bertrand
- Christiane Branlant
Nucleic Acids Research ; Volume: 42 ; Page: 2015-2036
Molecular basis for the antiparasitic activity of a mercaptoacetamide derivative that inhibits histone deacetylase 8 (HDAC8) from the human pathogen schistosoma mansoni
- D Stolfa
- Martin Marek
- J Lancelot
- A Hauser
- A Walter
- E Leproult
- J Melesina
- T Rumpf
- Jean-Marie Wurtz
- Jean Cavarelli
- W Sippl
- R Pierce
- Christophe Romier
- Matthieu Jung
Journal of Molecular Biology ; Volume: 426 ; Page: 3442-3453
TAF4, a subunit of transcription factor II D, directs promoter occupancy of nuclear receptor HNF4A during post-natal hepatocyte differentiation
- Daniil Alpern
- Diana Langer
- Benoit Ballester
- Stephanie Le Gras
- Christophe Romier
- Gabrielle Mengus
- Irwin Davidson
eLife ; Volume: 3 ; Page: 308-312
2013
Structural Basis for the Inhibition of Histone Deacetylase 8 (HDAC8), a Key Epigenetic Player in the Blood Fluke Schistosoma mansoni
- Martin Marek
- Srinivasaraghavan Kannan
- Alexander-Thomas Hauser
- Marina Moraes Mourão
- Stéphanie Caby
- Vincent Cura
- Diana A Stolfa
- Karin Schmidtkunz
- Julien Lancelot
- Luiza Andrade
- Jean-Paul Renaud
- Guilherme Oliveira
- Wolfgang Sippl
- Manfred Jung
- Jean Cavarelli
- Raymond J Pierce
- Christophe Romier
PLoS Pathogens ; Volume: 9
2012
TFIID TAF6-TAF9 complex formation involves the HEAT repeat-containing C-terminal domain of TAF6 and is modulated by TAF5 protein.
- Elisabeth Scheer
- Frédéric Delbac
- Laszlo Tora
- Dino Moras
- Christophe Romier
Journal of Biological Chemistry ; Volume: 287 ; Page: 27580-92