GenomEast
Leader : Christelle THIBAULT-CARPENTIER
Stephanie LE GRAS
Engineer
slegras@igbmc.fr
Platform(s) / Service(s)
Research platforms
Publications
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2025
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Accelerated epigenetic aging in Huntington’s disease involves polycomb repressive complex 1
- Baptiste Brulé
- Rafael Alcalá-Vida
- Noémie Penaud
- Jil Scuto
- Coline Mounier
- Jonathan Seguin
- Sina Vincent Khodaverdian
- Brigitte Cosquer
- Etienne Birmelé
- Stéphanie Le Gras
- Charles Decraene
- Anne-Laurence Boutillier
- Karine Merienne
Nature Communications ; Volume: 16 ; Page: 1550
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2024
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RNA polymerase II transcription initiation in holo-TFIID-depleted mouse embryonic stem cells
- Vincent Hisler
- Paul Bardot
- Dylane Detilleux
- Andrea Bernardini
- Matthieu Stierle
- Emmanuel Garcia Sanchez
- Claire Richard
- Lynda Hadj Arab
- Cynthia Ehrhard
- Bastien Morlet
- Yavor Hadzhiev
- Matthieu Jung
- Stéphanie Le Gras
- Luc Négroni
- Ferenc Müller
- László Tora
- Stéphane Vincent
Cell Reports ; Volume: 43 ; Page: 114791
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Dysregulated expression of cholesterol biosynthetic genes in Alzheimer's disease alters epigenomic signatures of hippocampal neurons
- Isabel Paiva
- Jonathan Seguin
- Iris Grgurina
- Akash Kumar Singh
- Brigitte Cosquer
- Damien Plassard
- Laura Tzeplaeff
- Stephanie Le Gras
- Ludovica Cotellessa
- Charles Decraene
- Johanne Gambi
- Rafael Alcala-Vida
- Muthusamy Eswaramoorthy
- Luc Buée
- Jean-Christophe Cassel
- Paolo Giacobini
- David Blum
- Karine Merienne
- Tapas Kundu
- Anne-Laurence Boutillier
Neurobiology of Disease ; Volume: 198 ; Page: 106538
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Dysregulated expression of cholesterol biosynthetic genes in Alzheimer's disease alters epigenomic signatures of hippocampal neurons
- I. Paiva
- J. Seguin
- I. Grgurina
- A. K. Singh
- B. Cosquer
- D. Plassard
- L. Tzeplaeff
- S. Le Gras
- Ludovica Cotellessa
- C. Decraene
- J. Gambi
- R. Alcala-Vida
- M. Eswaramoorthy
- Luc Buee
- J. C. Cassel
- Paolo Giacobini
- David Blum
- K. Merienne
- T. K. Kundu
- A. L. Boutillier
Neurobiology of Disease ; Volume: 198 ; Page: 106538
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2023
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MBD4 loss results in global reactivation of promoters and retroelements with low methylated CpG density
- Christophe Papin
- Abdulkhaleg Ibrahim
- Jamal Sabir
- Stéphanie Le Gras
- Isabelle Stoll
- Raed Albiheyri
- Ali Zari
- Ahmed Bahieldin
- Alfonso Bellacosa
- Christian Bronner
- Ali Hamiche
Journal of experimental & clinical cancer research ; Volume: 42 ; Page: 301
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Super-enhancer-driven expression of BAHCC1 promotes melanoma cell proliferation and genome stability
- Pietro Berico
- Maguelone Nogaret
- Max Cigrang
- Antonin Lallement
- Fatemeh Vand-Rajabpour
- Amanda Flores-Yanke
- Giovanni Gambi
- Guillaume Davidson
- Leane Seno
- Julian Obid
- Bujamin Vokshi
- Stephanie Le Gras
- Gabrielle Mengus
- Tao Ye
- Carlos Fernandez Cordero
- Mélanie Dalmasso
- Emmanuel Compe
- Corine Bertolotto
- Eva Hernando
- Irwin Davidson
- ...
Cell Reports ; Volume: 42 ; Page: 113363
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Mutant FUS induces chromatin reorganization in the hippocampus and alters memory processes
- Laura Tzeplaeff
- Jonathan Seguin
- Stéphanie Le Gras
- Salim Megat
- Brigitte Cosquer
- Damien Plassard
- Stéphane Dieterlé
- Isabel Paiva
- Gina Picchiarelli
- Charles Decraene
- Rafael Alcalá-Vida
- Jean-Christophe Cassel
- Karine Merienne
- Luc Dupuis
- Anne-Laurence Boutillier
Progress in Neurobiology ; Volume: 227 ; Page: 102483
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Mitotic chromosome condensation resets chromatin to safeguard transcriptional homeostasis during interphase
- Lucía Ramos-Alonso
- Petter Holland
- Stéphanie Le Gras
- Xu Zhao
- Bernard Jost
- Magnar Bjørås
- Yves Barral
- Jorrit Enserink
- Pierre Chymkowitch
Proceedings of the National Academy of Sciences of the United States of America ; Volume: 120
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Analysis of the P. lividus sea urchin genome highlights contrasting trends of genomic and regulatory evolution in deuterostomes
- Ferdinand Marlétaz
- Arnaud Couloux
- Julie Poulain
- Karine Labadie
- Corinne da Silva
- Sophie Mangenot
- Benjamin Noel
- Albert J Poustka
- Philippe Dru
- Cinta Pegueroles
- Marco Borra
- Elijah K Lowe
- Guy Lhomond
- Lydia Besnardeau
- Stéphanie Le Gras
- Tao Ye
- Daria Gavriouchkina
- Roberta Russo
- Caterina Costa
- Francesca Zito
- ...
Cell Genomics ; Volume: 3 ; Page: 100295
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Multi-Omics Data Integration Reveals Sex-Dependent Hippocampal Programming by Maternal High-Fat Diet during Lactation in Adult Mouse Offspring
- Thibaut Gauvrit
- Hamza Benderradji
- Alexandre Pelletier
- Soulaimane Aboulouard
- Emilie Faivre
- Kévin Carvalho
- Aude Deleau
- Emmanuelle Vallez
- Agathe Launay
- Anna Bogdanova
- Mélanie Besegher
- Stéphanie Le Gras
- Anne Tailleux
- Michel Salzet
- Luc Buée
- Fabien Delahaye
- David Blum
- Didier Vieau
Nutrients ; Volume: 15 ; Page: 4691
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