FRIDAY LECTURES: Selective sorting at the heart of the cell: Dirk Görlich unveils the mechanisms of disordered proteins, Friday, January 9, 3 PM, IGBMC Auditorium
The IGBMC is pleased to welcome Dirk Görlich, Director at the Max Planck Institute for Multidisciplinary Sciences in Göttingen and recipient of the 2025 Lasker Award, one of the highest honors in biomedical research.
A visionary researcher, Dirk Görlich is recognized for his pioneering work on disordered protein regions and their role in the organization and functioning of cells.
A Smart Barrier at the Heart of the Cell
Dirk Görlich has revealed how the FG domains of nuclear pores form a sophisticated selective filter:
A molecular “gel” that blocks unwanted molecules while allowing essential transporters and their cargo to pass.
A discovery that opens the field of biomolecular condensates and transforms our understanding of cellular organization.
His work also explains how certain viruses, such as HIV, hijack this system to enter the cell nucleus, offering new therapeutic avenues.
International Recognition
The 2025 Lasker Award, often seen as a precursor to the Nobel Prize, honors his work on disordered proteins, shared with Steven McKnight.
This research is crucial for understanding neurodegenerative diseases such as ALS and Huntington’s disease.
An Exceptional Meeting organized and hosted by Izabela Sumara, this event offers a unique opportunity to discover how the cell decides what enters, what stays out, and how these invisible mechanisms govern life.