Yann HERAULT

Researcher
yann.herault@igbmc.fr

Research team(s)

Pathophysiology of Down's syndrome and rare dose-effect diseases causing intellectual disabilities (ID) or autism spectrum disorders (ASD) and other comorbidities
Team Leader : Yann HERAULT
Department : Translational medecine and neurogenetics

Research subgroup(s)

Aging, Down's syndrome and Alzheimer's disease
Leader : Yann HERAULT
Teams : Pathophysiology of Down's syndrome and rare dose-effect diseases causing intellectual disabilities (ID) or autism spectrum disorders (ASD) and other comorbidities
Modeling of "genotype-phenotype" relationships and therapeutic approach in Down syndrome
Leader : Yann HERAULT
Teams : Pathophysiology of Down's syndrome and rare dose-effect diseases causing intellectual disabilities (ID) or autism spectrum disorders (ASD) and other comorbidities
neurobiology of 16p11.2 and 17q21.31syndromes and other genetic diseases with ID or ASD
Leader : Yann HERAULT
Teams : Pathophysiology of Down's syndrome and rare dose-effect diseases causing intellectual disabilities (ID) or autism spectrum disorders (ASD) and other comorbidities

Publications

2022
- Overproduction of hydrogen sulfide, generated by cystathionine β-synthase, disrupts brain wave patterns and contributes to neurobehavioral dysfunction in a rat model of down syndrome
  - Theodora Panagaki
  - Laura Lozano-Montes
  - Lucia Janickova
  - Karim Zuhra
  - Marcell Szabo
  - Tomas Majtan
  - Gregor Rainer
  - Damien Maréchal
  - Yann Herault
  - Csaba Szabo
  Redox Biology ; Volume: 51 ; Page: 102233
  HAL DOI
- INFRAFRONTIER quality principles in systemic phenotyping
  - Hilke Ehlich
  - Heather Cater
  - Ann Flenniken
  - Isabelle Goncalves da Cruz
  - Anne-Marie Mura
  - Vasileios Ntafis
  - Michael Raess
  - Mohammed Selloum
  - Claudia Stoeger
  - Sarka Suchanova
  - Reetta Vuolteenaho
  - Steve Brown
  - Yann Hérault
  - Reetta Hinttala
  - Martin Hrabě de Angelis
  - George Kollias
  - Dimitris Kontoyiannis
  - Bernard Malissen
  - Colin Mckerlie
  - Radislav Sedláček
  - ...
  Mammalian Genome ; Volume: 33 ; Page: 120-122
  HAL DOI
- EOSC-Life -D1.3 EOSC-Life EOSC FAIR services deployment for open calls
  - Helen Parkinson
  - Philip Gribbon
  - Ugis Sarkans
  - Gesa Witt
  - Andrea Zaliani
  - Manfred Kohler
  - Jason Swedlow
  - Jean-Marie Burel
  - Morris Swertz
  - Esther van Enckevort
  - Petr Holub
  - Marzia Massimi
  - Rafaele Matteoni
  - Holger Maier
  - Reetta Hinttala
  - Anne Heikkinen
  - Philipp Gormanns
  - Laurent Vasseur
  - Sophie Leblanc
  - Yann Herault
  - ...
  HAL DOI
- Behavioral Testing Design for Evaluation of Cognitive Disabilities
  - Fabrice Riet
  - Christophe Mittelhaeuser
  - Aline Lux
  - Raphael Bour
  - Mohammed Selloum
  - Tania Sorg
  - Yann Herault
  - Hamid Meziane
  Current Protocols ; Volume: 2
  HAL DOI
- Structure-Activity Relationship in the Leucettine Family of Kinase Inhibitors
  - Tania Tahtouh
  - Emilie Durieu
  - Benoit Villiers
  - Celine Bruyere
  - Thu Lan Nguyen
  - Xavier Fant
  - Kwang H. Ahn
  - Leepakshi Khurana
  - Emmanuel Deau
  - Mattias F. Lindberg
  - Elodie Severe
  - Frederic Miege
  - Didier Roche
  - Emmanuelle Limanton
  - Jean-Martial L'Helgoual'Ch
  - Guillaume Burgy
  - Solene Guiheneuf
  - Yann Hérault
  - Debra A. Kendall
  - François Carreaux
  - ...
  Journal of Medicinal Chemistry ; Volume: 65 ; Page: 1396-1417
  HAL DOI
- HRAS germline mutations impair LKB1/AMPK signaling and mitochondrial homeostasis in Costello syndrome models
  - Laetitia Dard
  - Christophe Hubert
  - Pauline Esteves
  - Wendy Blanchard
  - Ghina Bou About
  - Lyla Baldasseroni
  - Elodie Dumon
  - Chloe Angelini
  - Mégane Delourme
  - Veronique Guyonnet-Duperat
  - Stephane Claverol
  - Laura Fontenille
  - Karima Kissa
  - Pierre-Emmanuel Seguela
  - Jean-Benoit Thambo
  - Nicolas Levy
  - Yann Hérault
  - Nadege Bellance
  - Nivea Dias Amoedo
  - Frédérique Magdinier
  - ...
  JOURNAL OF CLINICAL INVESTIGATION ; Volume: 132
  HAL DOI
- The Human SCN9AR185H Point Mutation Induces Pain Hypersensitivity and Spontaneous Pain in Mice
  - Yaping Xue
  - Mélanie Kremer
  - Maria del Mar Muniz Moreno
  - Celeste Chidiac
  - Romain Lorentz
  - Marie-Christine Birling
  - Michel Barrot
  - Yann Herault
  - Claire Gaveriaux-Ruff
  Frontiers in Molecular Neuroscience ; Volume: 15 ; Page: 913990
  HAL DOI
- Possible association of 16p11.2 copy number variation with altered lymphocyte and neutrophil counts
  - Giuliana Giannuzzi
  - Nicolas Chatron
  - Katrin Mannik
  - Chiara Auwerx
  - Sylvain Pradervand
  - Gilles Willemin
  - Kendra Hoekzema
  - Xander Nuttle
  - Jacqueline Chrast
  - Marie Sadler
  - Eleonora Porcu
  - Nicolas Chatron
  - Katrin Männik
  - Damien Sanlaville
  - Caroline Schluth-Bolard
  - Cédric Le Caignec
  - Mathilde Nizon
  - Sandra Martin
  - Sébastien Jacquemont
  - Armand Bottani
  - ...
  npj Genomic Medicine ; Volume: 7 ; Page: 38
  HAL DOI
2021
- The Human SCN10AG1662S Point Mutation Established in Mice Impacts on Mechanical, Heat, and Cool Sensitivity
  - Céleste Chidiac
  - Yaping Xue
  - Maria del Mar Muniz Moreno
  - Ameer Abu Bakr Rasheed
  - Romain Lorentz
  - Marie-Christine Birling
  - Claire Gaveriaux-Ruff
  - Yann Herault
  Frontiers in Pharmacology ; Volume: 12 ; Page: 780132
  HAL DOI
- HDAC inhibitor ameliorates behavioral deficits in Mecp2308/y mouse model of Rett syndrome
  - Nicolas Lebrun
  - Chloé Delépine
  - Mohamed Selloum
  - Hamid Meziane
  - Juliette Nectoux
  - Yann Herault
  - Thierry Bienvenu
  Brain Research ; Volume: 1772 ; Page: 147670
  HAL DOI

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Yann HERAULT

Research team(s)

Research subgroup(s)

Publications

2022

2021