Pathophysiology of Down's syndrome and rare dose-effect diseases causing intellectual disabilities (ID) or autism spectrum disorders (ASD) and other comorbidities
Team Leader : Yann HERAULT
Department : Translational medecine and neurogenetics
Yann HERAULT
Researcher
yann.herault@igbmc.fr
Research team(s)
Research subgroup(s)
Publications
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2023
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Timeline of Developmental Defects Generated upon Genetic Inhibition of the Retinoic Acid Receptor Signaling Pathway
- Marius Teletin
- Manuel Mark
- Olivia Wendling
- Nadège Vernet
- Betty Féret
- Muriel Klopfenstein
- Yann Herault
- Norbert B Ghyselinck
Biomedicines ; Volume: 11
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Gdaphen, R pipeline to identify the most important qualitative and quantitative predictor variables from phenotypic data
- Maria del Mar Muniz Moreno
- Claire Gaveriaux-Ruff
- Yann Hérault
BMC Bioinformatics ; Volume: 24 ; Page: 28
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2022
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A 16p11.2 deletion mouse model displays quantitatively and qualitatively different behaviours in sociability and social novelty over short- and long-term observation
- Anna Rusu
- Claire Chevalier
- Fabrice de Chaumont
- Valérie Nalesso
- Véronique Brault
- Yann Hérault
- Elodie Ey
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Large-Scale Functional Assessment of Genes Involved in Rare Diseases with Intellectual Disabilities Unravels Unique Developmental and Behaviour Profiles in Mouse Models
- Hamid Meziane
- Marie-Christine Birling
- Olivia Wendling
- Sophie Leblanc
- Aline Dubos
- Mohammed Selloum
- Guillaume Pavlovic
- Tania Sorg
- Vera M. Kalscheuer
- Pierre Billuart
- Frédéric Laumonnier
- Jamel Chelly
- Hans van Bokhoven
- Yann Hérault
Biomedicines ; Volume: 10
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Analysis of genome-wide knockout mouse database identifies candidate ciliopathy genes
- Kendall Higgins
- Bret A. Moore
- Zorana Berberovic
- Hibret A. Adissu
- Mohammad Eskandarian
- Ann M. Flenniken
- Andy Shao
- Denise M. Imai
- Dave Clary
- Louise Lanoue
- Susan Newbigging
- Lauryl M. J. Nutter
- David J. Adams
- Fatima Bosch
- Robert E. Braun
- Steve D. M. Brown
- Mary E. Dickinson
- Michael Dobbie
- Paul Flicek
- Xiang Gao
- ...
Scientific Reports ; Volume: 12
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Ts66Yah, a mouse model of Down syndrome with improved construct and face validity
- Arnaud Duchon
- Maria del Mar Muñiz Moreno
- Claire Chevalier
- Valérie Nalesso
- Philippe Andre
- Marta Fructuoso-Castellar
- Mary Mondino
- Chrystelle Po
- Vincent Noblet
- Marie-Christine Birling
- Marie-Claude Potier
- Yann Herault
Disease Models & Mechanisms ; Volume: 15 ; Page: dmm049721
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Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease
- Julia Viard
- Yann Loe-Mie
- Rachel Daudin
- Malik Khelfaoui
- Christine Plancon
- Anne Boland
- Francisco Tejedor
- Richard L. Huganir
- Eunjoon Kim
- Makoto Kinoshita
- Guofa Liu
- Volker Haucke
- Thomas Moncion
- Eugene Yu
- Valérie Hindie
- Henri Bléhaut
- Clotilde Mircher
- Yann Hérault
- Jean-François Deleuze
- Jean-Christophe Rain
- ...
Life Science Alliance ; Volume: 5
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INFRAFRONTIER quality principles in systemic phenotyping
- Hilke Ehlich
- Heather Cater
- Ann Flenniken
- Isabelle Goncalves da Cruz
- Anne-Marie Mura
- Vasileios Ntafis
- Michael Raess
- Mohammed Selloum
- Claudia Stoeger
- Sarka Suchanova
- Reetta Vuolteenaho
- Steve Brown
- Yann Hérault
- Reetta Hinttala
- Martin Hrabě de Angelis
- George Kollias
- Dimitris Kontoyiannis
- Bernard Malissen
- Colin Mckerlie
- Radislav Sedláček
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Mammalian Genome ; Volume: 33 ; Page: 120-122
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Structure-Activity Relationship in the Leucettine Family of Kinase Inhibitors
- Tania Tahtouh
- Emilie Durieu
- Benoit Villiers
- Celine Bruyere
- Thu Lan Nguyen
- Xavier Fant
- Kwang H. Ahn
- Leepakshi Khurana
- Emmanuel Deau
- Mattias F. Lindberg
- Elodie Severe
- Frederic Miege
- Didier Roche
- Emmanuelle Limanton
- Jean-Martial L'Helgoual'Ch
- Guillaume Burgy
- Solene Guiheneuf
- Yann Hérault
- Debra A. Kendall
- François Carreaux
- ...
Journal of Medicinal Chemistry ; Volume: 65 ; Page: 1396-1417
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Possible association of 16p11.2 copy number variation with altered lymphocyte and neutrophil counts
- Giuliana Giannuzzi
- Nicolas Chatron
- Katrin Mannik
- Chiara Auwerx
- Sylvain Pradervand
- Gilles Willemin
- Kendra Hoekzema
- Xander Nuttle
- Jacqueline Chrast
- Marie Sadler
- Eleonora Porcu
- Nicolas Chatron
- Katrin Männik
- Damien Sanlaville
- Caroline Schluth-Bolard
- Cédric Le Caignec
- Mathilde Nizon
- Sandra Martin
- Sébastien Jacquemont
- Armand Bottani
- ...
npj Genomic Medicine ; Volume: 7 ; Page: 38
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