Pathophysiology of Down's syndrome and rare dose-effect diseases causing intellectual disabilities (ID) or autism spectrum disorders (ASD) and other comorbidities
Team Leader : Yann HERAULT
Department : Translational medecine and neurogenetics
Yann HERAULT
Researcher
yann.herault@igbmc.fr
Research team(s)
Research subgroup(s)
Publications
2026
Article in a journal
Standardized Pipeline for Metabolism and Cognition in GO‐DS21 Mouse Model: Investigating Down Syndrome Comorbidities
- Mohammed Selloum
- Patricia Da Silva‐buttkus
- Fabrice Riet
- Nathalia R V Dragano
- Lillian Garrett
- Hugues Jacobs
- Sabine M Hölter
- Nicolas Torquet
- Birgit Rathkolb
- Loic Lindner
- Valerie Gailus‐durner
- Guillaume Pavlovic
- Li Chan
- Johannes Beckers
- Benoit Petit Demoulière
- Helmut Fuchs
- Elodie Ey
- Tania Sorg
- Martin Hrabe De Angelis
- Yann Herault
Current Protocols ; Volume: 6
Article in a journal
Age‐related behavioral and molecular landmarks in new mouse models for studying Alzheimer's disease in Down syndrome
- Monika Rataj Baniowska
- Paige Mumford
- Francesca Prestia
- Pauline Stephan
- Millie Beament
- Marie‐christine Birling
- Chiara Lanzillotta
- Letizia Ciafardini
- Eugenio Barone
- Gloria Lau
- Claire Chevalier
- Chadia Nahy
- Nadia Messaddeq
- Thais Lestra
- Yixing Wu
- Valérie Nalesso
- Fabio Di Domenico
- Frances Wiseman
- Yann Herault
Alzheimer's & Dementia : the Journal of the Alzheimer's Association ; Volume: 22 ; Page: e71498
Article in a journal
Mapping the Brain Interaction Network of the Dual-Specificity, Tyrosine Phosphorylation-Regulated Kinase 1A (DYRK1A) Targeted by Leucettinib-21 Using Affinity Chromatography
- Emmanuel Deau
- Coralie Simon
- Gaëlle Hogrel
- Julien Caillette
- Julien Dairou
- Yann Herault
- Bastien Morlet
- Yoshihiko Miyata
- Laurent Meijer
- Mattias Lindberg
ACS Pharmacology & Translational Science ; Volume: 9 ; Page: 1204-1227
Article in a journal
Impaired vitamin D signaling reveals novel targets in tooth and alveolar bone
- Alexandra Jimenez-Armijo
- Alexandra Jimenez-Armijo
- Supawich Morkmued
- Eric Mathieu
- Valérie Fraulob
- Karen Niederreither
- Yann Herault
- Ariane Berdal
- Gilles Laverny
- Agnès Bloch-Zupan
Journal of Bone and Mineral Research
Article in a journal
Cdkn2a/p16Ink4a loss impairs Spatial memory independently of Alzheimer’s-associated genetic pathways in young adult mice
- Pauline Stephan
- Damien Plassard
- William M Keyes
- Yann Hérault
Cellular and Molecular Life Sciences ; Volume: 83 ; Page: 131
2025
Article in a journal
Better understanding of laboratory animal genetics will improve reproducibility
- Guillaume Pavlovic
- Sara Wells
- Yann Hérault
- Lydia Teboul
PLoS Biology ; Volume: 23 ; Page: e3003464
Article in a journal
Ripply3 overdosage induces mid-face shortening through Tbx1 downregulation in Down syndrome models
- José Tomás Ahumada Saavedra
- Claire Chevalier
- Agnes Bloch Zupan
- Yann Herault
PLoS Genetics ; Volume: 21 ; Page: e1011873
Article in a journal
Female C57BL/6J mice perform distinctive urination behaviour accompanied by ultrasonic vocalisation sequences with a stereotyped temporal organisation
- Fabrice de Chaumont
- Gaëlle Yvenou
- Ana Perez-Villalba
- Yann Hérault
- Thomas Bourgeron
- Elodie Ey
Behavioural Brain Research ; Volume: 495 ; Page: 115788
Article in a journal
The PTCHD1 protein: A prominent actor in brain function and in neurodevelopmental disorders
- Dévina C Ung
- Stéphane Martin
- Yann Hérault
- Frédéric Laumonnier
Neuroscience and Biobehavioral Reviews ; Volume: 176 ; Page: 106307
Article in a journal
Interneuron migration defects during corticogenesis contribute to Dyrk1a haploinsufficiency syndrome pathogenesis
- Maria Victoria Hinckelmann
- Aline Dubos
- Victorine Artot
- Gabrielle Rudolf
- Thu Lan Nguyen
- Peggy Tilly
- Valérie Nalesso
- Maria del Mar Muniz Moreno
- Marie-Christine Birling
- Juliette Godin
- Véronique Brault
- Yann Herault
Molecular Psychiatry ; Volume: 30 ; Page: 5227-5244