Pathophysiology of Down's syndrome and rare dose-effect diseases causing intellectual disabilities (ID) or autism spectrum disorders (ASD) and other comorbidities
Team Leader : Yann HERAULT
Department : Translational medecine and neurogenetics
Yann HERAULT
Researcher
yann.herault@igbmc.fr
Research team(s)
Research subgroup(s)
Publications
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2024
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The Rogdi knockout mouse is a model for Kohlschütter–Tönz syndrome
- Alexandra Jimenez-Armijo
- Supawich Morkmued
- José Tomás Ahumada
- Naji Kharouf
- Yvan de Feraudy
- Gergo Gogl
- Fabrice Riet
- Karen Niederreither
- Jocelyn Laporte
- Marie Christine Birling
- Mohammed Selloum
- Yann Hérault
- Magali Hernandez
- Agnès Bloch-Zupan
Scientific Reports ; Volume: 14 ; Page: 445
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The COL6A5-p.Glu2272* mutation induces chronic itch in mice
- Ameer Abu Bakr Rasheed
- Marie-Christine Birling
- Giuseppe Lauria
- Claire Gaveriaux-Ruff
- Yann Hérault
Mammalian Genome ; Volume: 35 ; Page: 122-134
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2023
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How much do we know about the function of mammalian genes?
- Lydia Teboul
- Yann Hérault
- Sara Wells
- Guillaume Pavlovic
BMC Biology ; Volume: 21
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Stefin B Inhibits NLRP3 Inflammasome Activation via AMPK/mTOR Signalling
- Mojca Trstenjak-Prebanda
- Monika Biasizzo
- Klemen Dolinar
- Sergej Pirkmajer
- Boris Turk
- Véronique Brault
- Yann Herault
- Nataša Kopitar-Jerala
Cells ; Volume: 12 ; Page: 2731
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Interneuron migration defects during corticogenesis contribute to Dyrk1a haploinsufficiency syndrome pathogenesis via actomyosin dynamics deregulations
- Maria Victoria Hinckelmann
- Aline Dubos
- Victorine Artot
- Gabrielle Rudolf
- Thu Lan Nguyen
- Peggy Tilly
- Valérie Nalesso
- Maria del Mar Muniz Moreno
- Marie-Christine Birling
- Juliette Godin
- Véronique Brault
- Yann Herault
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Changes in social behavior with MAPK2 and KCTD13/CUL3 pathways alterations in two new outbred rat models for the 16p11.2 syndromes with autism spectrum disorders
- Sandra Martin Lorenzo
- Maria del Mar Muniz Moreno
- Helin Atas
- Marion Pellen
- Valérie Nalesso
- Wolfgang Raffelsberger
- Geraldine Prevost
- Loic Lindner
- Marie-Christine Birling
- Séverine Menoret
- Laurent Tesson
- Luc Negroni
- Jean-Paul Concordet
- Ignacio Anegon
- Yann Herault
Frontiers in Neuroscience ; Volume: 17 ; Page: 1148683
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Towards Preclinical Validation of Arbaclofen (R-baclofen) Treatment for 16p11.2 Deletion Syndrome
- Brigitta B Gundersen
- William T O’brien
- Melanie D Schaffler
- Maria N Schultz
- Tatsuya Tsukahara
- Sandra Martin Lorenzo
- Valérie Nalesso
- Alice H Luo Clayton
- Ted Abel
- Jacqueline N Crawley
- Sandeep Robert Datta
- Yann Herault
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Genome-wide screening reveals the genetic basis of mammalian embryonic eye development
- Justine M Chee
- Louise Lanoue
- Dave Clary
- Kendall Higgins
- Lynette Bower
- Ann Flenniken
- Ruolin Guo
- David J Adams
- Fatima Bosch
- Robert E Braun
- Steve D M Brown
- H.-J. Genie Chin
- Mary E Dickinson
- Chih-Wei Hsu
- Michael Dobbie
- Xiang Gao
- Sanjeev Galande
- Anne Grobler
- Jason D Heaney
- Yann Hérault
- ...
BMC Biology ; Volume: 21 ; Page: 22
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Increased On-Target Rate and Risk of Concatemerization after CRISPR-Enhanced Targeting in ES Cells
- Valérie Erbs
- Romain Lorentz
- Benjamin Eisenman
- Laurence Schaeffer
- Laurence Luppi
- Loic Lindner
- Yann Hérault
- Guillaume Pavlovic
- Marie Wattenhofer-Donzé
- Marie-Christine Birling
Genes ; Volume: 14 ; Page: 401
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Identifying foetal forebrain interneurons as a target for monogenic autism risk factors and the polygenic 16p11.2 microdeletion
- Yifei Yang
- Sam A Booker
- James M Clegg
- Idoia Quintana-Urzainqui
- Anna Sumera
- Zrinko Kozic
- Owen Dando
- Sandra Martin Lorenzo
- Yann Hérault
- Peter C Kind
- David J Price
- Thomas Pratt
BMC Neuroscience ; Volume: 24 ; Page: 5
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