Pathophysiology of Down's syndrome and rare dose-effect diseases causing intellectual disabilities (ID) or autism spectrum disorders (ASD) and other comorbidities
Team Leader : Yann HERAULT
Department : Translational medecine and neurogenetics
Yann HERAULT
Researcher
yann.herault@igbmc.fr
Research team(s)
Research subgroup(s)
Publications
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2018
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Synaptic dysfunction in amygdala in intellectual disorder models
- Marianne Aincy
- Hamid Meziane
- Yann Herault
- Yann Humeau
Progress in Neuro-Psychopharmacology and Biological Psychiatry ; Volume: 84 ; Page: 392-397
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A Population Study of Common Ocular Abnormalities in C57BL/6N rd8 Mice
- Bret A Moore
- Michel Roux
- Lionel Sebbag
- Ann Cooper
- Sydney G Edwards
- Brian C Leonard
- Denise M Imai
- Stephen Griffey
- Lynette Bower
- Dave Clary
- K. C Kent Lloyd
- Yann Hérault
- Sara M Thomasy
- Christopher J Murphy
- Ala Moshiri
Investigative Ophthalmology & Visual Science ; Volume: 59 ; Page: 2252
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Ptchd1 deficiency induces excitatory synaptic and cognitive dysfunctions in mouse
- D. Ung
- G Iacono
- H Méziane
- E. Blanchard
- M-A Papon
- M Selten
- J-R van Rhijn
- R Montjean
- J Rucci
- Stéphane Martin
- A Fleet
- M-C Birling
- S Marouillat
- R Roepman
- M Selloum
- A. Lux
- R-A Thépault
- P Hamel
- K Mittal
- J. Vincent
- ...
Molecular Psychiatry ; Volume: 23 ; Page: 1356-1367
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A new mouse model of ARX dup24 recapitulates the patients' behavioral and fine motor alterations
- Aline Dubos
- Hamid Meziane
- Giovanni Iacono
- Aurore Curie
- Fabrice Riet
- Christelle Martin
- Nadège Loaec
- Marie-Christine Birling
- Mohammed Selloum
- Elisabeth Normand
- Guillaume Pavlovic
- Tania Sorg
- Henk G. Stunnenberg
- Jamel Chelly
- Yann Humeau
- Gaëlle Friocourt
- Yann Herault
Human Molecular Genetics ; Volume: 27 ; Page: 2138-2153
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Translating molecular advances in Down syndrome and Fragile X syndrome into therapies
- Victor Faundez
- Ilario de Toma
- Barbara Bardoni
- Renata Bartesaghi
- Dean Nizetic
- Rafael de la Torre
- Roi Cohen Kadosh
- Yann Hérault
- Mara Dierssen
- Marie-Claude Potier
- Stylianos Antonarakis
- Renata Bartesaghi
- Andrea Contestabile
- Tonnie Coppus
- Peter de Deyn
- Alain Dekker
- Jean-Maurice Delabar
- Mara Dierssen
- Elisabeth Fisher
- Yann Hérault
- ...
European Neuropsychopharmacology ; Volume: 28 ; Page: 675--690
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Hepatocyte SHP deficiency protects mice from acetaminophen-evoked liver injury in a JNK-signaling regulation and GADD45beta-dependent manner
- Yong-Hoon Kim
- Jung-Ran Noh
- Jung Hwan Hwang
- Kyoung-Shim Kim
- Dong-Hee Choi
- Jae-Hoon Kim
- Sung Je Moon
- Ji Hyun Choi
- Yann Herault
- Tae Geol Lee
- Hueng-Sik Choi
- Chul-Ho Lee
Archives of Toxicology ; Volume: 92 ; Page: 2563-2572
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Identification of genetic elements in metabolism by high-throughput mouse phenotyping
- Jan Rozman
- Birgit Rathkolb
- Manuela Oestereicher
- Chrsitine Schutt
- Akash Chavan Ravindranath
- Stefanie Leuchtenberger
- Sapna Sharma
- Martin Kistler
- Monja Willershauser
- Robert Brommage
- Terrence Meehan
- Jeremy Mason
- Hamed Haselimashhadi
- Tertius Hough
- Ann-Marie Mallon
- Sara Wells
- Luis Santos
- Christopher Lelliott
- Jacqueline White
- Tania Sorg-Guss
- ...
Nature Communications ; Volume: 9
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Increased H3K9 methylation and impaired expression of Protocadherins are associated with the cognitive dysfunctions of the Kleefstra syndrome
- G. Iacono
- A. Dubos
- H. Meziane
- M. Benevento
- E. Habibi
- A. Mandoli
- F. Riet
- M. Selloum
- Robert Feil
- H. Zhou
- T. Kleefstra
- N. N. Kasri
- H. Van Bokhoven
- Y. Herault
- H. G. Stunnenberg
Nucleic Acids Research ; Volume: 46 ; Page: 4950–4965
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2017
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WD40-repeat 47, a microtubule-associated protein, is essential for brain development and autophagy
- Meghna Kannan
- Efil Bayam
- Christel Wagner
- Bruno Rinaldi
- Perrine Kretz
- Peggy Tilly
- Marna Roos
- Lara Mcgillewie
- Séverine Bär
- Shilpi Minocha
- Claire Chevalier
- Chrystelle Po
- Jamel Chelly
- Jean-Louis Mandel
- Renato Borgatti
- Amélie Piton
- Craig Kinnear
- Ben Loos
- David Adams
- Yann Herault
- ...
Proceedings of the National Academy of Sciences of the United States of America ; Volume: 114 ; Page: E9308-E9317
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A large scale hearing loss screen reveals an extensive unexplored genetic landscape for auditory dysfunction
- Michael Bowl
- Michelle Simon
- Neil Ingham
- Simon Greenaway
- Luis Santos
- Heather Cater
- Sarah Taylor
- Jeremy Mason
- Natalja Kurbatova
- Selina Pearson
- Lynette Bower
- Dave Clary
- Hamid Meziane
- Patrick Reilly
- Osamu Minowa
- Lois Kelsey
- Glauco Tocchini-Valentini
- Xiang Gao
- Allan Bradley
- William Skarnes
- ...
Nature Communications ; Volume: 8
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