Pathophysiology of Down's syndrome and rare dose-effect diseases causing intellectual disabilities (ID) or autism spectrum disorders (ASD) and other comorbidities
Team Leader : Yann HERAULT
Department : Translational medecine and neurogenetics
Yann HERAULT
Researcher
yann.herault@igbmc.fr
Research team(s)
Research subgroup(s)
Publications
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2013
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Article in a journal
Epigallocatechin‐3‐gallate, a DYRK1A inhibitor, rescues cognitive deficits in D own syndrome mouse models and in humans
- Rafael de la Torre
- Susana de Sola
- Meritxell Pons
- Arnaud Duchon
- María Martínez de Lagran
- Magí Farré
- Montserrat Fitó
- Bessy Benejam
- Klaus Langohr
- Joan Rodriguez
- Mitona Pujadas
- Jean Charles Bizot
- Aída Cuenca
- Nathalie Janel
- Silvina Catuara
- Maria Isabel Covas
- Henri Blehaut
- Yann Hérault
- Jean Marie Delabar
- Mara Dierssen
Molecular Nutrition and Food Research ; Volume: 58 ; Page: 278-288
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Article in a journal
FELASA guidelines for the refinement of methods for genotyping genetically-modified rodents
- Paolo Cinelli
- Eleni Douni
- Yann Hérault
- Alex Maas
- Pirjo Pakarinen
- Matti Poutanen
- Mirentxu Santos Lafuente
- Ferdinando Scavizzi
Laboratory Animals ; Volume: 47 ; Page: 134-145
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Article in a journal
Surveying the Down syndrome mouse model resource identifies critical regions responsible for chronic otitis media
- Mahmood F. Bhutta
- Michael T. Cheeseman
- Yann Hérault
- Yuejin E. Yu
- Steve D. M. Brown
Mammalian Genome ; Volume: 24 ; Page: 439--445
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Article in a journal
DYRK1A overexpression decreases plasma lecithin:cholesterol acyltransferase activity and apolipoprotein A-I levels
- Asma Tlili
- Christophe Noll
- Sandrine Middendorp
- Arnaud Duchon
- Marie Jouan
- Eva Benabou
- Yann Hérault
- Jean-Louis Paul
- Jean-Maurice Delabar
- Nathalie Janel
Molecular Genetics and Metabolism ; Volume: 110 ; Page: 371--377
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Article in a journal
The homeodomain factor Gbx1 is required for locomotion and cell specification in the dorsal spinal cord
- Hamid Meziane
- Valérie Fraulob
- Fabrice Riet
- Wojciech Krezel
- Mohammed Selloum
- Michaela Geffarth
- Dario Acampora
- Yann Hérault
- Antonio Simeone
- Michael Brand
- Pascal Dollé
- Muriel Rhinn
PeerJ ; Volume: 1 ; Page: e142
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2012
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Article in a journal
The App-Runx1 Region Is Critical for Birth Defects and Electrocardiographic Dysfunctions Observed in a Down Syndrome Mouse Model
- Matthieu Raveau
- Jacques Lignon
- Valérie Nalesso
- Arnaud Duchon
- Yoram Groner
- Andrew Sharp
- Doulaye Dembele
- Véronique Brault
- Yann Hérault
PLoS Genetics ; Volume: 8 ; Page: e1002724
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Article in a journal
Highly‐efficient, fluorescent, locus directed cre and FlpO deleter mice on a pure C57BL/6N genetic background
- Marie-Christine Birling
- Andrée Dierich
- Sylvie Jacquot
- Yann Hérault
- Guillaume Pavlovic
Genesis - The Journal of Genetics and Development ; Volume: 50 ; Page: 482-489
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Article in a journal
DYRK1A: A master regulatory protein controlling brain growth
- Fayçal Guedj
- Patricia Lopes Pereira
- Sonia Najas
- Maria-Jose Barallobre
- Caroline Chabert
- Benoit Souchet
- Catherine Sebrie
- Catherine Verney
- Yann Hérault
- Mariona Arbones
- Jean M Delabar
Neurobiology of Disease ; Volume: 46 ; Page: 190--203
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Article in a journal
Mouse large-scale phenotyping initiatives: overview of the European Mouse Disease Clinic (EUMODIC) and of the Wellcome Trust Sanger Institute Mouse Genetics Project
- Abdelkader Ayadi
- Marie-Christine Birling
- Joanna Bottomley
- James Bussell
- Helmut Fuchs
- Martin Fray
- Valérie Gailus-Durner
- Simon Greenaway
- Richard Houghton
- Natasha Karp
- Sophie Leblanc
- Christoph Lengger
- Holger Maier
- Ann-Marie Mallon
- Susan Marschall
- David Melvin
- Hugh Morgan
- Guillaume Pavlovic
- Ed Ryder
- William C. Skarnes
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Mammalian Genome ; Volume: 23 ; Page: 600-610
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Chapter of the book
The in vivo Down syndrome genomic library in mouse
- Yann Hérault
- Véronique Brault
- Arnaud Duchon
- Emilie Velot
- Damien Marechal
Progress in Brain Research ; Volume: 197 ; Page: 169--197
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