Pathophysiology of Down's syndrome and rare dose-effect diseases causing intellectual disabilities (ID) or autism spectrum disorders (ASD) and other comorbidities
Team Leader : Yann HERAULT
Department : Translational medecine and neurogenetics
Yann HERAULT
Researcher
yann.herault@igbmc.fr
Research team(s)
Research subgroup(s)
Publications
-
2018
-
A new mouse model of ARX dup24 recapitulates the patients' behavioral and fine motor alterations
- Aline Dubos
- Hamid Meziane
- Giovanni Iacono
- Aurore Curie
- Fabrice Riet
- Christelle Martin
- Nadège Loaec
- Marie-Christine Birling
- Mohammed Selloum
- Elisabeth Normand
- Guillaume Pavlovic
- Tania Sorg
- Henk G. Stunnenberg
- Jamel Chelly
- Yann Humeau
- Gaëlle Friocourt
- Yann Herault
Human Molecular Genetics ; Volume: 27 ; Page: 2138-2153
-
Hepatocyte SHP deficiency protects mice from acetaminophen-evoked liver injury in a JNK-signaling regulation and GADD45beta-dependent manner
- Yong-Hoon Kim
- Jung-Ran Noh
- Jung Hwan Hwang
- Kyoung-Shim Kim
- Dong-Hee Choi
- Jae-Hoon Kim
- Sung Je Moon
- Ji Hyun Choi
- Yann Herault
- Tae Geol Lee
- Hueng-Sik Choi
- Chul-Ho Lee
Archives of Toxicology ; Volume: 92 ; Page: 2563-2572
-
Translating molecular advances in Down syndrome and Fragile X syndrome into therapies
- Victor Faundez
- Ilario de Toma
- Barbara Bardoni
- Renata Bartesaghi
- Dean Nizetic
- Rafael de la Torre
- Roi Cohen Kadosh
- Yann Hérault
- Mara Dierssen
- Marie-Claude Potier
- Stylianos Antonarakis
- Renata Bartesaghi
- Andrea Contestabile
- Tonnie Coppus
- Peter de Deyn
- Alain Dekker
- Jean-Maurice Delabar
- Mara Dierssen
- Elisabeth Fisher
- Yann Hérault
- ...
European Neuropsychopharmacology ; Volume: 28 ; Page: 675--690
-
-
2017
-
WD40-repeat 47, a microtubule-associated protein, is essential for brain development and autophagy
- Meghna Kannan
- Efil Bayam
- Christel Wagner
- Bruno Rinaldi
- Perrine Kretz
- Peggy Tilly
- Marna Roos
- Lara Mcgillewie
- Séverine Bär
- Shilpi Minocha
- Claire Chevalier
- Chrystelle Po
- Jamel Chelly
- Jean-Louis Mandel
- Renato Borgatti
- Amélie Piton
- Craig Kinnear
- Ben Loos
- David Adams
- Yann Herault
- ...
Proceedings of the National Academy of Sciences of the United States of America ; Volume: 114 ; Page: E9308-E9317
-
A large scale hearing loss screen reveals an extensive unexplored genetic landscape for auditory dysfunction
- Michael Bowl
- Michelle Simon
- Neil Ingham
- Simon Greenaway
- Luis Santos
- Heather Cater
- Sarah Taylor
- Jeremy Mason
- Natalja Kurbatova
- Selina Pearson
- Lynette Bower
- Dave Clary
- Hamid Meziane
- Patrick Reilly
- Osamu Minowa
- Lois Kelsey
- Glauco Tocchini-Valentini
- Xiang Gao
- Allan Bradley
- William Skarnes
- ...
Nature Communications ; Volume: 8
-
Prevalence of sexual dimorphism in mammalian phenotypic traits
- Natasha Karp
- Jeremy Mason
- Arthur Beaudet
- Yoav Benjamini
- Lynette Bower
- Robert Braun
- Steve Brown
- Elissa Chesler
- Mary Dickinson
- Ann Flenniken
- Helmut Fuchs
- Martin Hrabe de Angelis
- Xiang Gao
- Shiying Guo
- Simon Greenaway
- Ruth Heller
- Yann Herault
- Monica Justice
- Natalja Kurbatova
- Christopher Lelliott
- ...
Nature Communications ; Volume: 8
-
Fluorescent nanodiamond tracking reveals intraneuronal transport abnormalities induced by brain-disease-related genetic risk factors
- Simon Haziza
- Nitin Mohan
- Yann Loe-Mie
- Aude-Marie Lepagnol-Bestel
- Sophie Massou
- Marie-Pierre Adam
- Xuan Loc Le
- Julia Viard
- Christine Plancon
- Rachel Daudin
- Pascale Koebel
- Emilie Dorard
- Christiane Rose
- Feng-Jen Hsieh
- Chih-Che Wu
- Brigitte Potier
- Yann Hérault
- Carlo Sala
- Aiden Corvin
- Bernadette Allinquant
- ...
Nature Nanotechnology ; Volume: 12 ; Page: 322-328
-
Nox4 genetic inhibition in experimental hypertension and metabolic syndrome
- Ghina Bouabout
- Estelle Ayme-Dietrich
- Hugues Jacobs
- Marie-France Champy Methlin
- Marie-Christine Birling
- Guillaume Pavlovic
- Lola Madeira
- Lahcen El Fertak
- Benoît Petit-Demoulière
- Tania Sorg-Guss
- Yann Hérault
- John Mudgett
- Laurent Monassier
Archives of cardiovascular diseases ; Volume: 111 ; Page: 41-52
-
Rodent models in Down syndrome research: impact and future opportunities
- Yann Herault
- Jean M. Delabar
- Elizabeth M. C. Fisher
- Victor L. J. Tybulewicz
- Eugene Yu
- Veronique Brault
Disease Models & Mechanisms ; Volume: 23 ; Page: 578-589
-
Efficient and rapid generation of large genomic variants in rats and mice using CRISMERE
- Marie-Christine Birling
- Laurence Schaeffer
- Philippe Andre
- Loic Lindner
- Damien Marechal
- Abdelkader Ayadi
- Tania Sorg-Guss
- Guillaume Pavlovic
- Yann Herault
Scientific Reports ; Volume: 7
-