Pathophysiology of Down's syndrome and rare dose-effect diseases causing intellectual disabilities (ID) or autism spectrum disorders (ASD) and other comorbidities
Team Leader : Yann HERAULT
Department : Translational medecine and neurogenetics
Yann HERAULT
Researcher
yann.herault@igbmc.fr
Research team(s)
Research subgroup(s)
Publications
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2017
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Dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A) inhibitors: a survey of recent patent literature
- T.L. Nguyen
- Corinne Fruit
- Y. Hérault
- L. Meijer
- Thierry Besson
Expert Opinion on Therapeutic Patents ; Volume: 27 ; Page: 1183-1199
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A Fast, Easy, and Customizable Eight-Color Flow Cytometric Method for Analysis of the Cellular Content of Bronchoalveolar Lavage Fluid in the Mouse
- Francois Daubeuf
- Julien Becker
- Juan Aguilar-Pimentel
- Claudine Ebel
- Martin Hrabě de Angelis
- Yann Herault
- Nelly Frossard
Current Protocols in Mouse Biology ; Volume: 7 ; Page: 88-99
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Identification d'une nouvelle ADN méthyltransférase « DNMT3C » qui protège les cellules germinales mâles de l'activité des transposons
- Joan Barau
- Aurélie Teissandier
- Natasha Zamudio
- Stéphanie Roy
- Valerie Nalesso
- Yann Hérault
- Florian Guillou
- Deborah Bourc'His
Page: np
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Introduction to Mammalian Genome Special Issue: Genome Editing
- Lydia Teboul
- Yann Herault
- Cynthia Smith
- Bruce Whitelaw
Mammalian Genome ; Volume: 28 ; Page: 235-236
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Disease model discovery from 3,328 gene knockouts by The International Mouse Phenotyping Consortium
- Terrence Meehan
- Nathalie Conte
- David West
- Julius Jacobsen
- Jeremy Mason
- Jonathan Warren
- Chao Chen
- Ilinca Tudose
- Mike Relac
- Peter Matthews
- Natasha Karp
- Luis Santos
- Tanja Fiegel
- Natalie Ring
- Henrik Westerberg
- Simon Greenaway
- Duncan Sneddon
- Hugh Morgan
- Gemma Codner
- Michelle Stewart
- ...
Nature Genetics ; Volume: 49 ; Page: 1231-1238
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Mouse models of 17q21.31 microdeletion and microduplication syndromes highlight the importance of Kansl1 for cognition
- Thomas Arbogast
- G Iacono
- C Chevalier
- N Afinowi
- X Houbaert
- M van Eede
- C Laliberte
- Marie-Christine Birling
- K Linda
- H Meziane
- M Selloum
- T Sorg
- N Nadif Kasri
- D Koolen
- H Stunnenberg
- R Henkelman
- M Kopanitsa
- Yann Humeau
- B de Vries
- Yann Herault
PLoS Genetics ; Volume: 13
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Atp6ap2 ablation in adult mice impairs viability through multiple organ deficiencies
- Olivia Wendling
- Marie-France Champy Methlin
- Solène Jaubert
- Guillaume Pavlovic
- Aline Dubos
- Loic Lindner
- Hugues Jacobs
- Manuel Mark
- Roy Combe
- Isabelle Goncalves da Cruz
- Hervé Luche
- John Mudgett
- Thomas Rosahl
- Tania Sorg-Guss
- Marie Malissen
- Patrick Reilly
- Yann Herault
Scientific Reports ; Volume: 7
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Modeling human disease in rodents by CRISPR/Cas9 genome editing
- Marie-Christine Birling
- Yann Herault
- Guillaume Pavlovic
Mammalian Genome ; Volume: 28 ; Page: 291-301
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2016
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Physiological Expression of AMPKγ2 Mutation Causes Wolff-Parkinson-White Syndrome and Induces Kidney Injury in Mice
- Xiaodong Yang
- John Mudgett
- Ghina Bou About
- Marie-France Champy Methlin
- Hugues Jacobs
- Laurent Monassier
- Guillaume Pavlovic
- Tania Sorg-Guss
- Yann Hérault
- Benoît Petit-Demoulière
- Ku Lu
- Wen Feng
- Hongwu Wang
- Li-Jun Ma
- Roger Askew
- Mark D. Erion
- David E. Kelley
- Robert W. Myers
- Cai Li
- Hong-Ping Guan
Journal of Biological Chemistry ; Volume: 291 ; Page: 23428-23439
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Fasudil treatment in adult reverses behavioural changes and brain ventricular enlargement in Oligophrenin-1 mouse model of intellectual disability
- Hamid Meziane
- Malik Khelfaoui
- Noemi Morello
- Bassem Hiba
- Eleonora Calcagno
- Sophie Reibel-Foisset
- Mohammed Selloum
- Jamel Chelly
- Yann Humeau
- Fabrice Riet
- Ginevra Zanni
- Yann Hérault
- Thierry Bienvenu
- Maurizio Giustetto
- Pierre Billuart
Human Molecular Genetics ; Volume: 25 ; Page: 2314-2323
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