Integrated Structural Biology
Leader : Catherine BIRCK
Alastair MC EWEN
Platform(s) / Service(s)
Research platforms
Publications
2026
Article in a journal
STARD3 regulates lysosome positioning and contacts via a GSK3-controlled phosphorylation switch
- Julie Eichler
- Corinne Wendling
- Sophie Huver
- Mehdi Zouiouich
- Victor Hanss
- Anna Cardinal
- Victoria Fimbel
- Catherine Birck
- Alastair G Mcewen
- Céline Knorr
- Catherine Fromental-Ramain
- Maxime Boutry
- Marie-Pierre Chenard
- Guillaume Drin
- Catherine Tomasetto
- Fabien Alpy
The EMBO Journal ; Volume: 45 ; Page: 2239-2277
2025
Pre-publication, Working Document » Preprint/Prepublication
Structural analysis of HERC2/UBE3A and HERC2/DOCK10 complexes provides new insights into the molecular basis of Angelman, Angelman-like and Dup15q Syndromes
- Auguste Demenge
- Jiawen Lim
- Arpoudamarie Roc
- Boglarka Zambo
- Gergo Gogl
- Alexandra Cousido-Siah
- Alastair G Mcewen
- Anna Bonhoure
- Camille Kostmann
- Christine Fagotto-Kaufmann
- Pascal Eberling
- Judit Osz-Papai
- Alberto Podjarny
- Eduardo Howard
- Christelle Golzio
- Anne Debant
- Susanne Schmidt
- Gilles Travé
Article in a journal
The adaptability of the fungal tRNA ligase’s ATP-binding pocket: a potential target for new antifungal drugs
- Alastair G Mcewen
- Alessandro Giovinazzo
- Pierre Poussin-Courmontagne
- Matilde Merolle
- Glauco P Tocchini-Valentini
- Manuela Pellegrini
- Giuseppe D Tocchini-Valentini
NAR Molecular Medicine ; Volume: 2
Article in a journal
The Holdup Multiplex, an assay for high-throughput measurement of protein-ligand affinity constants using a mass-spectrometry readout
- François Delalande
- So̷ren Østergaard
- Gergő Gógl
- Alexandra Cousido-Siah
- Alastair G Mcewen
- Yushi Men
- Farida Salimova
- Aurélien Rohrbacher
- Camille Kostmann
- Yves Nominé
- Renaud Vincentelli
- Pascal Eberling
- Christine Carapito
- Gilles Travé
- Elodie Monsellier
Journal of the American Chemical Society ; Volume: 147 ; Page: 10886-10902
2024
Article in a journal
Molecular mechanism of IKK catalytic dimer docking to NF-κB substrates
- Changqing Li
- Stefano Moro
- Kateryna Shostak
- Francis J O’reilly
- Mariel Donzeau
- Andrea Graziadei
- Alastair G Mcewen
- Dominique Desplancq
- Pierre Poussin-Courmontagne
- Thomas Bachelart
- Mert Fiskin
- Nicolas Berrodier
- Simon Pichard
- Karl Brillet
- Georges Orfanoudakis
- Arnaud Poterszman
- Vladimir Torbeev
- Juri Rappsilber
- Norman E Davey
- Alain Chariot
- ...
Nature Communications ; Volume: 15 ; Page: 7692
2023
Article in a journal
Asymmetric dimerization in a transcription factor superfamily is promoted by allosteric interactions with DNA
- Abdul Kareem Mohideen Patel
- Pierre Vilela
- Tajith Baba Shaik
- Alastair G Mcewen
- Isabelle Hazemann
- Karl Brillet
- Eric Ennifar
- Ali Hamiche
- Gabriel V Markov
- Vincent Laudet
- Dino Moras
- Bruno P Klaholz
- Isabelle M Billas
Nucleic Acids Research ; Volume: 51 ; Page: 8864-8879
Article in a journal
Crystal Structure of Staphopain C from Staphylococcus aureus
- Malgorzata Magoch
- Alastair McEwen
- Valeria Napolitano
- Benedykt Władyka
- Grzegorz Dubin
Molecules ; Volume: 28 ; Page: 4407
2022
Article in a journal
A novel nuclear receptor subfamily enlightens the origin of heterodimerization
- Brice Beinsteiner
- Gabriel V Markov
- Maxime Bourguet
- Alastair G Mcewen
- Stéphane Erb
- Abdul Kareem Mohideen Patel
- Fatima Z El Khaloufi El Khaddar
- Claire Lecroisey
- Guillaume Holzer
- Karim Essabri
- Isabelle Hazemann
- Ali Hamiche
- Sarah Cianférani
- Dino Moras
- Vincent Laudet
- Isabelle M L Billas
BMC Biology ; Volume: 20 ; Page: 217
2021
Article in a journal
The SOUL family of heme-binding proteins: Structure and function 15 years later
- Brian J. Goodfellow
- Filipe Freire
- Ana Luisa Carvalho
- Susana S. Aveiro
- Peggy Charbonnier
- Jean Marc Moulis
- Leonildo Delgado
- Gloria C. Ferreira
- João E. Rodrigues
- Pierre Poussin-Courmontagne
- Catherine Birck
- Alastair G Mcewen
- Anjos L. Macedo
Coordination Chemistry Reviews ; Volume: 448 ; Page: 214189
Article in a journal
A structural signature motif enlightens the origin and diversification of nuclear receptors
- Brice Beinsteiner
- Gabriel V Markov
- Stéphane Erb
- Yassmine Chebaro
- Alastair G Mcewen
- Sarah Cianférani
- Vincent Laudet
- Dino Moras
- Isabelle M L Billas
PLoS Genetics ; Volume: 17 ; Page: e1009492