Regulation of gene expression in cancer
Team Leader : Irwin DAVIDSON
Department : Functional genomics and cancer
Irwin DAVIDSON
Researcher
irwin@igbmc.fr
Research team(s)
Publications
2025
Article in a journal
SETDB1 is critically required for uveal melanoma growth and represents a promising therapeutic target
- Imène Krossa
- Céline Pisibon
- Yann Cheli
- Karine Bille
- Mélanie Dalmasso
- Sabah Hamadat
- Chrystel Husser
- Marie Irondelle
- Julien Cherfils-Vicini
- Frédéric Soysouvanh
- Sacha Nahon-Esteve
- Arnaud Martel
- Sandra Lassalle
- Jean-Pierre Caujolle
- Célia Maschi
- Stéphanie Baillif
- Dan Hasson
- Saul Carcamo
- Andrew E Aplin
- Irwin Davidson
- ...
Cell Death and Disease ; Volume: 16 ; Page: 754
Article in a journal
BDH2-driven lysosome-to-mitochondria iron transfer shapes ferroptosis vulnerability of the melanoma cell states
- Francesca Rizzollo
- Abril Escamilla-Ayala
- Nicola Fattorelli
- Natalia Barbara Lysiak
- Sanket More
- Pablo Hernández Varas
- Lucia Barazzuol
- Chris van den Haute
- Joris van Asselberghs
- David Nittner
- Jonathan Coene
- Vivek Venkataramani
- Bernhard Michalke
- Christine Gaillet
- Tatiana Cañeque
- Irwin Davidson
- Steven Verhelst
- Peter Vangheluwe
- Tito Calì
- Jean-Christophe Marine
- ...
Nature Metabolism ; Volume: 7 ; Page: 1851-1870
Article in a journal
Targeting GRPR for sex hormone-dependent cancer after loss of E-cadherin
- Jérémy H Raymond
- Zackie Aktary
- Marie Pouteaux
- Valérie Petit
- Flavie Luciani
- Maria Wehbe
- Patrick Gizzi
- Claire Bourban
- Didier Decaudin
- Fariba Némati
- Igor Martianov
- Irwin Davidson
- Catherine Tomasetto
- Richard M White
- Florence Mahuteau-Betzer
- Béatrice Vergier
- Lionel Larue
- Veronique Delmas
Nature ; Volume: 643 ; Page: 801 - 809
Article in a journal
Pan-inhibition of super-enhancer-driven oncogenic transcription by next-generation synthetic ecteinascidins yields potent anti-cancer activity
- Max Cigrang
- Julian Obid
- Maguelone Nogaret
- Leane Seno
- Tao Ye
- Guillaume Davidson
- Philippe Catez
- Pietro Berico
- Clara Capelli
- Clara Marechal
- Amélie Zachayus
- Clémence Elly
- Marie Jose Guillen Navarro
- Marta Martínez Diez
- Gema Santamaria Nunez
- Tsai-Kun Li
- Emmanuel Compe
- Pablo Avilés
- Irwin Davidson
- Jean-Marc Egly
- ...
Nature Communications ; Volume: 16 ; Page: 512
2024
Article in a journal
Changes in AXL and/or MITF melanoma subpopulations in patients receiving immunotherapy
- M. Willemsen
- J. Bulgarelli
- S.K. Chauhan
- R.R. Lereim
- D. Angeli
- G. Grisendi
- G. Krebbers
- I. Davidson
- J.A. Kyte
- M. Guidoboni
- Rosalie M Luiten
- W.J. Bakker
Immuno-Oncology and Technology ; Volume: 24 ; Page: 101009
Article in a journal
An atlas of the human liver diurnal transcriptome and its perturbation by hepatitis C virus infection.
- Atish Mukherji
- Frank Juehling
- Yogy Simanjuntak
- Emilie Crouchet
- Fabio del Zompo
- Yuji Teraoka
- Alexandre Haller
- Philippe Baltzinger
- Soumith Paritala
- Fahmida Rasha
- Naoto Fujiwara
- Cloé Gadenne
- Nevena Slovic
- Marine Oudot
- Sarah C. Durand
- Clara Ponsolles
- Catherine Schuster
- Xiaodong Zhuang
- Jacinta Holmes
- Ming-Lun Yeh
- ...
Nature Communications ; Volume: 15 ; Page: 7486
2023
Article in a journal
Mesenchymal-like Tumor Cells and Myofibroblastic Cancer-Associated Fibroblasts Are Associated with Progression and Immunotherapy Response of Clear Cell Renal Cell Carcinoma
- Guillaume Davidson
- Alexandra Helleux
- Yann Vano
- Veronique Lindner
- Antonin Fattori
- Marie Cerciat
- Reza T. Elaidi
- Virginie Verkarre
- Cheng-Ming Sun
- Christine Chevreau
- Mostefa Bennamoun
- Hervé Lang
- Thibault Tricard
- Wolf H. Fridman
- Catherine Sautes-Fridman
- Xiaoping Su
- Damien Plassard
- Céline Keime
- Christelle Thibault-Carpentier
- Philippe Barthelemy
- ...
Cancer Research ; Volume: 83 ; Page: 2952-2969
Article in a journal
SMARCB1 regulates a TFCP2L1-MYC transcriptional switch promoting renal medullary carcinoma transformation and ferroptosis resistance
- Bujamin Vokshi
- Guillaume Davidson
- Nassim Tawanaie Pour Sedehi
- Alexandra Helleux
- Marc Rippinger
- Alexandre Haller
- Justine Gantzer
- Jonathan Thouvenin
- Philippe Baltzinger
- Rachida Bouarich
- Valeria Manriquez
- Sakina Zaidi
- Priya Rao
- Pavlos Msaouel
- Xiaoping Su
- Hervé Lang
- Thibault Tricard
- Véronique Lindner
- Didier Surdez
- Jean-Emmanuel Kurtz
- ...
Nature Communications ; Volume: 14 ; Page: 3034
Article in a journal
Epigenomic mapping identifies an enhancer repertoire that regulates cell identity in bladder cancer through distinct transcription factor networks
- Hélène Neyret-Kahn
- Jacqueline Fontugne
- Xiang Yu Meng
- Clarice Groeneveld
- Luc Cabel
- Tao Ye
- Elodie Guyon
- Clémentine Krucker
- Florent Dufour
- Elodie Chapeaublanc
- Audrey Rapinat
- Daniel Jeffery
- Laura Tanguy
- Victoria Dixon
- Yann Neuzillet
- Thierry Lebret
- David Gentien
- Irwin Davidson
- Yves Allory
- Isabelle Bernard-Pierrot
- ...
Oncogene ; Volume: 42 ; Page: 1524-1542
Article in a journal
An Enhancer Demethylator Phenotype Converged to Immune Dysfunction and Resistance to Immune Checkpoint Inhibitors in Clear-Cell Renal Cell Carcinomas
- Xiaofan Lu
- Yann Vano
- Alexandra Helleux
- Xiaoping Su
- Veronique Lindner
- Guillaume Davidson
- Roger Mouawad
- Jean-Philippe Spano
- Morgan Rouprêt
- Reza Elaidi
- Eva Compérat
- Virginie Verkarre
- Chengming Sun
- Christine Chevreau
- Mostefa Bennamoun
- Hervé Lang
- Thibault Tricard
- Wenxuan Cheng
- Li Xu
- Irwin Davidson
- ...
Clinical Cancer Research ; Volume: 29 ; Page: 1279-1291