Chemical biophysics of transcriptional signaling
Team Leader : Annick DEJAEGERE
Department : Integrated structural biology
Natacha ROCHEL-GUIBERTEAU
Researcher
rochel@igbmc.fr
Research team(s)
Research subgroup(s)
Publications
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2022
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Article in a journal
Advances in vitamin D receptor function and evolution based on the 3D structure of the lamprey ligand binding domain
- Rita Sigüeiro
- Laurent Bianchetti
- Carole Peluso-Iltis
- Sandra Chalhoub
- Annick Dejaegere
- Judit Osz
- Natacha Rochel
Journal of Medicinal Chemistry ; Volume: 65 ; Page: 5821–5829
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Article in a journal
Development of novel Gemini-cholesterol analogues for retinoid-related orphan receptors
- Uxía Gómez-Bouzó
- Alioune Fall
- Judit Osz
- Yagamare Fall
- Natacha Rochel
- Hugo Santalla
Organic Chemistry Frontiers ; Volume: 9 ; Page: 1522-1530
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2021
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Article in a journal
Ligands and DNA in the allosteric control of retinoid receptors function
- Pierre Germain
- Natacha Rochel
- William Bourguet
Essays in Biochemistry ; Volume: 65 ; Page: 887-899
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Pre-publication, Working Document
PPARγ is a tumor suppressor in basal bladder tumors offering new potential therapeutic opportunities
- Laure Coutos-Thévenot
- Syrine Beji
- Hélène Neyret-Kahn
- Quentin Pippo
- Jacqueline Fontugne
- Judith Osz
- Clémentine Krucker
- Clarice dos Santos Groeneveld
- Florent Dufour
- Aurélie Kamoun
- Marie Ley
- Elodie Chapeaublanc
- Aurélien De Reynies
- Thierry Lebret
- Yves Allory
- Sarah Cianférani
- François Radvanyi
- Natacha Rochel
- Isabelle Bernard-Pierrot
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Article in a journal
Biological evaluation and synthesis of calcitroic acid
- Olivia Yu
- Daniel Webb
- Elliot Di Milo
- Tania Mutchie
- Kelly Teske
- Taosheng Chen
- Wenwei Lin
- Carole Peluso-Iltis
- Natacha Rochel
- Moritz Helmstädter
- Daniel Merk
- Leggy Arnold
Bioorganic Chemistry ; Volume: 116 ; Page: 105310
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Article in a journal
Design, synthesis and evaluation of side-chain hydroxylated derivatives of lithocholic acid as potent agonists of the vitamin D receptor (VDR)
- Carmen M González
- Sunil Gaikwad
- Gonzalo Lasanta
- Julian Loureiro
- Niclas Nilsson
- Carole Peluso-Iltis
- Natacha Rochel
- Antonio Mouriño
Bioorganic Chemistry ; Volume: 115 ; Page: 105202
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Article in a journal
Design, Synthesis, Evaluation and Structure of Allenic 1α,25‐Dihydroxyvitamin D 3 Analogs with Locked Mobility at C‐17
- Ramón Fraga
- Kateryna Len
- Regis Lutzing
- Gilles Laverny
- Julian Loureiro
- Miguel Maestro
- Natacha Rochel
- Enrique Rodriguez‐borges
- Antonio Mouriño
Chemistry - A European Journal ; Volume: 27 ; Page: 13384-13389
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Article in a journal
Lithocholic acid-based design of noncalcemic vitamin D receptor agonists
- Sunil Gaikwad
- Carmen González
- Daniel Vilariño
- Gonzalo Lasanta
- Carmen Villaverde
- Antonio Mouriño
- Lieve Verlinden
- Annemieke Verstuyf
- Carole Peluso-Iltis
- Natacha Rochel
- Klaudia Berkowska
- Ewa Marcinkowska
Bioorganic Chemistry ; Volume: 111 ; Page: 104878
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Article in a journal
Conformational editing of intrinsically disordered protein by α-methylation
- Valentin Bauer
- Boris Schmidtgall
- Gergő Gógl
- Jozica Dolenc
- Judit Osz
- Yves Nominé
- Camille Kostmann
- Alexandra Cousido-Siah
- André Mitschler
- Natacha Rochel
- Gilles Travé
- Bruno Kieffer
- Vladimir Torbeev
Chemical Science ; Volume: 12 ; Page: 1080-1089
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2020
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Article in a journal
Quercetin potentializes the respective cytotoxic activity of gemcitabine or doxorubicin on 3D culture of AsPC-1 or HepG2 cells, through the inhibition of HIF-1α and MDR1
- Sarah Hassan
- Jean Peluso
- Sandra Chalhoub
- Ysia Idoux-Gillet
- Nadia Benkirane-Jessel
- Natacha Rochel
- Guy Fuhrmann
- Genevieve Ubeaud-Sequier
PLoS ONE ; Volume: 15 ; Page: e0240676
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