Pathophysiology of Down's syndrome and rare dose-effect diseases causing intellectual disabilities (ID) or autism spectrum disorders (ASD) and other comorbidities
Team Leader : Yann HERAULT
Department : Translational medecine and neurogenetics
Yann HERAULT
Researcher
yann.herault@igbmc.fr
Research team(s)
Research subgroup(s)
Publications
-
2021
-
Article in a journal
Specific Susceptibility to COVID-19 in Adults with Down Syndrome
- Tomer Illouz
- Arya Biragyn
- Milana Frenkel-Morgenstern
- Orly Weissberg
- Alessandro Gorohovski
- Eugene Merzon
- Ilan Green
- Florencia Iulita
- Lisi Flores-Aguilar
- Mara Dierssen
- Ilario de Toma
- Hefziba Lifshitz
- Stylianos Antonarakis
- Eugene Yu
- Yann Herault
- Marie-Claude Potier
- Alexandra Botté
- Randall Roper
- Benjamin Sredni
- Ronit Sarid
- ...
NeuroMolecular Medicine ; Volume: 23 ; Page: 561–571
-
-
2020
-
Article in a journal
Mouse mutant phenotyping at scale reveals novel genes controlling bone mineral density
- Anna Swan
- Christine Schütt
- Jan Rozman
- Maria del Mar Muñiz Moreno
- Stefan Brandmaier
- Michelle Simon
- Stefanie Leuchtenberger
- Mark Griffiths
- Robert Brommage
- Piia Keskivali-Bond
- Harald Grallert
- Thomas Werner
- Raffaele Teperino
- Lore Becker
- Gregor Miller
- Ala Moshiri
- John Seavitt
- Derek Cissell
- Terrence Meehan
- Elif Acar
- ...
PLoS Genetics ; Volume: 16 ; Page: e1009190
-
Pre-publication, Working Document
BIN1 genetic risk factor for Alzheimer is sufficient to induce early structural tract alterations in entorhinal cortex-dentate gyrus pathway and related hippocampal multi-scale impairments
- R Daudin
- D Marechal
- Q Wang
- Y Abe
- N Bourg
- M Sartori
- Y Loe-Mie
- J Lipecka
- C Guerrera
- A Mckenzie
- B Potier
- P Dutar
- J Viard
- A.M Lepagnol-Bestel
- A Winkeler
- V Hindié
- Mc Birling
- L Lindner
- C Chevalier
- G Pavlovic
- ...
-
Pre-publication, Working Document
Chr21 protein-protein interactions: enrichment in products involved in intellectual disabilities, autism and Late Onset Alzheimer Disease
- Julia Viard
- Yann Loe-Mie
- Rachel Daudin
- Malik Khelfaoui
- Christine Plancon
- Anne Boland
- Francisco Tejedor
- Richard Huganir
- Eunjoon Kim
- Makoto Kinoshita
- Guofa Liu
- Volker Haucke
- Thomas Moncion
- Eugene Yu
- Valérie Hindie
- Henri Bléhaut
- Clotilde Mircher
- Yann Herault
- Jean-François Deleuze
- Jean-Christophe Rain
- ...
-
Article in a journal
Mechanism of cystathionine-β-synthase inhibition by disulfiram: The role of bis(N,N-diethyldithiocarbamate)-copper(II)
- Karim Zuhra
- Theodora Panagaki
- Elisa Randi
- Fiona Augsburger
- Marc Blondel
- Gaelle Friocourt
- Yann Herault
- Csaba Szabo
Biochemical Pharmacology ; Volume: 182 ; Page: 114267
-
Pre-publication, Working Document
Pioglitazone improves deficits of Fmr1-KO mouse model of Fragile X syndrome by interfering with excessive diacylglycerol signaling
- Andréa Geoffroy
- Karima Habbas
- Boglarka Zambo
- Laetitia Schramm
- Arnaud Duchon
- Eric Flatter
- Laetitia Fouillen
- Julie Zumsteg
- Dimitri Heintz
- Jean-Louis Mandel
- Yann Hérault
- Hervé Moine
-
Article in a journal
Variability in Genome Editing Outcomes: Challenges for Research Reproducibility and Clinical Safety
- Lydia Teboul
- Yann Herault
- Sara Wells
- Waseem Qasim
- Guillaume Pavlovic
Molecular Therapy ; Volume: 28 ; Page: 1422-1431
-
Article in a journal
Introduction to Mammalian Genome Special Issue: Epigenetics
- Johannes Beckers
- Raffaele Teperino
- Yann Hérault
- Martin Hrabé de Angelis
Mammalian Genome ; Volume: 31 ; Page: 117-118
-
Article in a journal
Human and mouse essentiality screens as a resource for disease gene discovery
- Pilar Cacheiro
- Violeta Muñoz-Fuentes
- Stephen Murray
- Mary Dickinson
- Maja Bucan
- Lauryl Nutter
- Kevin Peterson
- Hamed Haselimashhadi
- Ann Flenniken
- Hugh Morgan
- Henrik Westerberg
- Tomasz Konopka
- Chih-Wei Hsu
- Audrey Christiansen
- Denise Lanza
- Arthur Beaudet
- Jason Heaney
- Helmut Fuchs
- Valerie Gailus-Durner
- Tania Sorg
- ...
Nature Communications ; Volume: 11
-
Article in a journal
A Small Compound Targeting Prohibitin with Potential Interest for Cognitive Deficit Rescue in Aging mice and Tau Pathology Treatment
- Anne-Cécile Guyot
- Charlotte Leuxe
- Clémence Disdier
- Nassima Oumata
- Narciso Costa
- Gwenaëlle Le Roux
- Paloma Fernandez-Varela
- Arnaud Duchon
- Jean Baptiste Charbonnier
- Yann Herault
- Serena Pavoni
- Hervé Galons
- Emile Andriambeloson
- Stéphanie Wagner
- Laurent Meijer
- Amie K. Lund
- Aloïse Mabondzo
Scientific Reports ; Volume: 10 ; Page: 1143
-