Yann HERAULT

Researcher
yann.herault@igbmc.fr

Research team(s)

Pathophysiology of Down's syndrome and rare dose-effect diseases causing intellectual disabilities (ID) or autism spectrum disorders (ASD) and other comorbidities
Team Leader : Yann HERAULT
Department : Translational medecine and neurogenetics

Research subgroup(s)

Aging, Down's syndrome and Alzheimer's disease
Leader : Yann HERAULT
Teams : Pathophysiology of Down's syndrome and rare dose-effect diseases causing intellectual disabilities (ID) or autism spectrum disorders (ASD) and other comorbidities
Modeling of "genotype-phenotype" relationships and therapeutic approach in Down syndrome
Leader : Yann HERAULT
Teams : Pathophysiology of Down's syndrome and rare dose-effect diseases causing intellectual disabilities (ID) or autism spectrum disorders (ASD) and other comorbidities
neurobiology of 16p11.2 and 17q21.31syndromes and other genetic diseases with ID or ASD
Leader : Yann HERAULT
Teams : Pathophysiology of Down's syndrome and rare dose-effect diseases causing intellectual disabilities (ID) or autism spectrum disorders (ASD) and other comorbidities

Publications

2023
- Timeline of Developmental Defects Generated upon Genetic Inhibition of the Retinoic Acid Receptor Signaling Pathway
  - Marius Teletin
  - Manuel Mark
  - Olivia Wendling
  - Nadège Vernet
  - Betty Féret
  - Muriel Klopfenstein
  - Yann Herault
  - Norbert B Ghyselinck
  Biomedicines ; Volume: 11
  HAL DOI
- Development of HPV16 mouse and dog models for more accurate prediction of human vaccine efficacy
  - Emmanuelle Totain
  - Loic Lindner
  - Nicolas Martin
  - Yolande Misseri
  - Alexandra Iché
  - Marie-Christine Birling
  - Tania Sorg
  - Yann Hérault
  - Alain Bousquet-Melou
  - Pascale Bouillé
  - Christine Duthoit
  - Guillaume Pavlovic
  - Severine Boullier
  Laboratory Animal Research ; Volume: 39 ; Page: 14
  HAL DOI
- Day-to-day spontaneous social behaviours is quantitatively and qualitatively affected in a 16p11.2 deletion mouse model
  - Anna Rusu
  - Claire Chevalier
  - Fabrice de Chaumont
  - Valérie Nalesso
  - Véronique Brault
  - Yann Hérault
  - Elodie Ey
  Frontiers in Behavioral Neuroscience ; Volume: 17 ; Page: 1294558
  HAL DOI
- Dissecting the autism-associated 16p11.2 locus identifies multiple drivers in neuroanatomical phenotypes and unveils a male-specific role for the major vault protein
  - Perrine Kretz
  - Christel Wagner
  - Anna Mikhaleva
  - Charlotte Montillot
  - Sylvain Hugel
  - Ilaria Morella
  - Meghna Kannan
  - Marie-Christine Fischer
  - Maxence Milhau
  - Ipek Yalcin
  - Riccardo Brambilla
  - Mohammed Selloum
  - Yann Hérault
  - Alexandre Reymond
  - Stephan Collins
  - Binnaz Yalcin
  Genome Biology ; Volume: 24 ; Page: 261
  HAL DOI
- Gdaphen, R pipeline to identify the most important qualitative and quantitative predictor variables from phenotypic data
  - Maria del Mar Muniz Moreno
  - Claire Gaveriaux-Ruff
  - Yann Hérault
  BMC Bioinformatics ; Volume: 24 ; Page: 28
  HAL DOI
2022
- A 16p11.2 deletion mouse model displays quantitatively and qualitatively different behaviours in sociability and social novelty over short- and long-term observation
  - Anna Rusu
  - Claire Chevalier
  - Fabrice de Chaumont
  - Valérie Nalesso
  - Véronique Brault
  - Yann Hérault
  - Elodie Ey
  HAL DOI
- Large-Scale Functional Assessment of Genes Involved in Rare Diseases with Intellectual Disabilities Unravels Unique Developmental and Behaviour Profiles in Mouse Models
  - Hamid Meziane
  - Marie-Christine Birling
  - Olivia Wendling
  - Sophie Leblanc
  - Aline Dubos
  - Mohammed Selloum
  - Guillaume Pavlovic
  - Tania Sorg
  - Vera M. Kalscheuer
  - Pierre Billuart
  - Frédéric Laumonnier
  - Jamel Chelly
  - Hans van Bokhoven
  - Yann Hérault
  Biomedicines ; Volume: 10
  HAL DOI
- Analysis of genome-wide knockout mouse database identifies candidate ciliopathy genes
  - Kendall Higgins
  - Bret A. Moore
  - Zorana Berberovic
  - Hibret A. Adissu
  - Mohammad Eskandarian
  - Ann M. Flenniken
  - Andy Shao
  - Denise M. Imai
  - Dave Clary
  - Louise Lanoue
  - Susan Newbigging
  - Lauryl M. J. Nutter
  - David J. Adams
  - Fatima Bosch
  - Robert E. Braun
  - Steve D. M. Brown
  - Mary E. Dickinson
  - Michael Dobbie
  - Paul Flicek
  - Xiang Gao
  - ...
  Scientific Reports ; Volume: 12
  HAL DOI
- Ts66Yah, a mouse model of Down syndrome with improved construct and face validity
  - Arnaud Duchon
  - Maria del Mar Muñiz Moreno
  - Claire Chevalier
  - Valérie Nalesso
  - Philippe Andre
  - Marta Fructuoso-Castellar
  - Mary Mondino
  - Chrystelle Po
  - Vincent Noblet
  - Marie-Christine Birling
  - Marie-Claude Potier
  - Yann Herault
  Disease Models & Mechanisms ; Volume: 15 ; Page: dmm049721
  HAL DOI
- Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease
  - Julia Viard
  - Yann Loe-Mie
  - Rachel Daudin
  - Malik Khelfaoui
  - Christine Plancon
  - Anne Boland
  - Francisco Tejedor
  - Richard L. Huganir
  - Eunjoon Kim
  - Makoto Kinoshita
  - Guofa Liu
  - Volker Haucke
  - Thomas Moncion
  - Eugene Yu
  - Valérie Hindie
  - Henri Bléhaut
  - Clotilde Mircher
  - Yann Hérault
  - Jean-François Deleuze
  - Jean-Christophe Rain
  - ...
  Life Science Alliance ; Volume: 5
  HAL DOI

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Yann HERAULT

Research team(s)

Research subgroup(s)

Publications

2023

2022