Pathophysiology of Down's syndrome and rare dose-effect diseases causing intellectual disabilities (ID) or autism spectrum disorders (ASD) and other comorbidities
Team Leader : Yann HERAULT
Department : Translational medecine and neurogenetics
Yann HERAULT
Researcher
yann.herault@igbmc.fr
Research team(s)
Research subgroup(s)
Publications
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2023
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Article in a journal
Changes in social behavior with MAPK2 and KCTD13/CUL3 pathways alterations in two new outbred rat models for the 16p11.2 syndromes with autism spectrum disorders
- Sandra Martin Lorenzo
- Maria del Mar Muniz Moreno
- Helin Atas
- Marion Pellen
- Valérie Nalesso
- Wolfgang Raffelsberger
- Geraldine Prevost
- Loic Lindner
- Marie-Christine Birling
- Séverine Menoret
- Laurent Tesson
- Luc Negroni
- Jean-Paul Concordet
- Ignacio Anegon
- Yann Herault
Frontiers in Neuroscience ; Volume: 17 ; Page: 1148683
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Pre-publication, Working Document
Towards Preclinical Validation of Arbaclofen (R-baclofen) Treatment for 16p11.2 Deletion Syndrome
- Brigitta B Gundersen
- William T O’brien
- Melanie D Schaffler
- Maria N Schultz
- Tatsuya Tsukahara
- Sandra Martin Lorenzo
- Valérie Nalesso
- Alice H Luo Clayton
- Ted Abel
- Jacqueline N Crawley
- Sandeep Robert Datta
- Yann Herault
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Article in a journal
Increased On-Target Rate and Risk of Concatemerization after CRISPR-Enhanced Targeting in ES Cells
- Valérie Erbs
- Romain Lorentz
- Benjamin Eisenman
- Laurence Schaeffer
- Laurence Luppi
- Loic Lindner
- Yann Hérault
- Guillaume Pavlovic
- Marie Wattenhofer-Donzé
- Marie-Christine Birling
Genes ; Volume: 14 ; Page: 401
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Article in a journal
Genome-wide screening reveals the genetic basis of mammalian embryonic eye development
- Justine M Chee
- Louise Lanoue
- Dave Clary
- Kendall Higgins
- Lynette Bower
- Ann Flenniken
- Ruolin Guo
- David J Adams
- Fatima Bosch
- Robert E Braun
- Steve D M Brown
- H.-J. Genie Chin
- Mary E Dickinson
- Chih-Wei Hsu
- Michael Dobbie
- Xiang Gao
- Sanjeev Galande
- Anne Grobler
- Jason D Heaney
- Yann Hérault
- ...
BMC Biology ; Volume: 21 ; Page: 22
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Article in a journal
Identifying foetal forebrain interneurons as a target for monogenic autism risk factors and the polygenic 16p11.2 microdeletion
- Yifei Yang
- Sam A Booker
- James M Clegg
- Idoia Quintana-Urzainqui
- Anna Sumera
- Zrinko Kozic
- Owen Dando
- Sandra Martin Lorenzo
- Yann Hérault
- Peter C Kind
- David J Price
- Thomas Pratt
BMC Neuroscience ; Volume: 24 ; Page: 5
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Article in a journal
Timeline of Developmental Defects Generated upon Genetic Inhibition of the Retinoic Acid Receptor Signaling Pathway
- Marius Teletin
- Manuel Mark
- Olivia Wendling
- Nadège Vernet
- Betty Féret
- Muriel Klopfenstein
- Yann Herault
- Norbert B Ghyselinck
Biomedicines ; Volume: 11
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Article in a journal
Dissecting the autism-associated 16p11.2 locus identifies multiple drivers in neuroanatomical phenotypes and unveils a male-specific role for the major vault protein
- Perrine Kretz
- Christel Wagner
- Anna Mikhaleva
- Charlotte Montillot
- Sylvain Hugel
- Ilaria Morella
- Meghna Kannan
- Marie-Christine Fischer
- Maxence Milhau
- Ipek Yalcin
- Riccardo Brambilla
- Mohammed Selloum
- Yann Hérault
- Alexandre Reymond
- Stephan Collins
- Binnaz Yalcin
Genome Biology ; Volume: 24 ; Page: 261
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Article in a journal
Gdaphen, R pipeline to identify the most important qualitative and quantitative predictor variables from phenotypic data
- Maria del Mar Muniz Moreno
- Claire Gaveriaux-Ruff
- Yann Hérault
BMC Bioinformatics ; Volume: 24 ; Page: 28
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Article in a journal
Development of HPV16 mouse and dog models for more accurate prediction of human vaccine efficacy
- Emmanuelle Totain
- Loic Lindner
- Nicolas Martin
- Yolande Misseri
- Alexandra Iché
- Marie-Christine Birling
- Tania Sorg
- Yann Hérault
- Alain Bousquet-Melou
- Pascale Bouillé
- Christine Duthoit
- Guillaume Pavlovic
- Severine Boullier
Laboratory Animal Research ; Volume: 39 ; Page: 14
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Article in a journal
Day-to-day spontaneous social behaviours is quantitatively and qualitatively affected in a 16p11.2 deletion mouse model
- Anna Rusu
- Claire Chevalier
- Fabrice de Chaumont
- Valérie Nalesso
- Véronique Brault
- Yann Hérault
- Elodie Ey
Frontiers in Behavioral Neuroscience ; Volume: 17 ; Page: 1294558
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