Christophe ROMIER

Publications

• 2017

  • Design, Multicomponent Synthesis, and Anticancer Activity of a Focused Histone Deacetylase (HDAC) Inhibitor Library with Peptoid-Based Cap Groups

    • Viktoria Krieger
    • Alexandra Hamacher
    • Christoph Gertzen
    • Johanna Senger
    • Martijn Zwinderman
    • Martin Marek
    • Christophe Romier
    • Frank Dekker
    • Thomas Kurz
    • Manfred Jung
    • Holger Gohlke
    • Matthias Kassack
    • Finn Hansen

    Journal of Medical Chemistry ; Volume: 60 ; Page: 5493-5506

    HAL DOI

  • Histone deacetylase inhibition modulates histone acetylation at gene promoter regions and affects genome-wide gene transcription in Schistosoma mansoni

    • Leticia Anderson
    • Monete Gomes
    • Lucas Dasilva
    • Adriana da Silva Andrade Pereira
    • Marina Mourão
    • Christophe Romier
    • Raymond Pierce
    • Sergio Verjovski-Almeida

    PLoS Neglected Tropical Diseases ; Volume: 11

    HAL DOI

• 2016

  • Molecular basis and specificity of H2A.Z–H2B recognition and deposition by the histone chaperone YL1

    • Chrysa Latrick
    • Martin Marek
    • Khalid Ouararhni
    • Christophe Papin
    • Isabelle Stoll
    • Maria Ignatyeva
    • Arnaud Obri
    • Eric Ennifar
    • Stefan Dimitrov
    • Christophe Romier
    • Ali Hamiche

    Nature Structural and Molecular Biology ; Volume: 23 ; Page: 309-316

    HAL DOI

  • Synthesis and Biological Investigation of Oxazole Hydroxamates as Highly Selective Histone Deacetylase 6 (HDAC6) Inhibitors

    • J. Senger
    • J. Melesina
    • Martin Marek
    • Christophe Romier
    • I. Oehme
    • O. Witt
    • W. Sippl
    • M. Jung

    Journal of Medicinal Chemistry ; Volume: 59 ; Page: 1545-55

    HAL DOI

  • Combattre les maladies négligées en ciblant sélectivement leurs enzymes épigénétiques : le cas de la désacétylase 8 (HDAC8) de Schistosoma mansoni

    • Martin Marek
    • Tajith Baba Shaik
    • Manfred Jung
    • Wolfgang Sippl
    • Raymond J. Pierce
    • Christophe Romier

    Biologie Aujourd'hui ; Volume: 210 ; Page: 311--320

    HAL DOI

  • Complex Reconstitution and Characterization by Combining Co-expression Techniques in Escherichia coli with High-Throughput

    • Renaud Vincentelli
    • Christophe Romier

    ADVANCED TECHNOLOGIES FOR PROTEIN COMPLEX PRODUCTION AND CHARACTERIZATION ; Volume: 896 ; Page: 43-58

    HAL DOI

  • Large-Scale Overproduction and Purification of Recombinant Histone Deacetylase 8 (HDAC8) from the Human-Pathogenic Flatworm Schistosoma mansoni

    • Martin Marek
    • Tajith Baba Shaik
    • Sylvie Duclaud
    • R. J. Pierce
    • Christophe Romier

    Methods in Molecular Biology ; Volume: 1436 ; Page: 109-18

    HAL DOI

• 2015

  • Characterization and Production of Protein Complexes by Co-expression in Escherichia coli

    • Matthias Haffke
    • Martin Marek
    • Martin Pelosse
    • Marie-Laure Diebold
    • Uwe Schlattner
    • Imre Berger
    • Christophe Romier

    Structural Proteomics ; Volume: 1261 ; Page: 63-89

    HAL DOI

  • Fluorescence-Based Screening Assays for the NAD+-Dependent Histone Deacetylase smSirt2 from Schistosoma mansoni

    • Matthias Schiedel
    • Martin Marek
    • Julien Lancelot
    • Berin Karaman
    • Ingrid Almlöf
    • Johan Schultz
    • Wolfgang Sippl
    • Raymond J. Pierce
    • Christophe Romier
    • Manfred Jung

    Journal of Biomolecular Screening ; Volume: 20 ; Page: 112-121

    HAL DOI

  • HDAC8: a multifaceted target for therapeutic interventions

    • Alokta Chakrabarti
    • Ina Oehme
    • Olaf Witt
    • Guilherme Oliveira
    • Wolfgang Sippl
    • Christophe Romier
    • Raymond J. Pierce
    • Manfred Jung

    Trends in Pharmacological Sciences ; Volume: 36 ; Page: 481-492

    HAL DOI