mRNA processing
Team Leader : Clement CHARENTON
Department : Integrated structural biology
Clement CHARENTON
Researcher
charentc@igbmc.fr
Research team(s)
Publications
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2025
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Article in a journal
Dominant variants in major spliceosome U4 and U5 small nuclear RNA genes cause neurodevelopmental disorders through splicing disruption
- Caroline Nava
- Benjamin Cogne
- Amandine Santini
- Elsa Leitão
- François Lecoquierre
- Yuyang Chen
- Sarah Stenton
- Thomas Besnard
- Solveig Heide
- Sarah Baer
- Abhilasha Jakhar
- Sonja Neuser
- Boris Keren
- Anne Faudet
- Sylvie Forlani
- Marie Faoucher
- Kevin Uguen
- Konrad Platzer
- Alexandra Afenjar
- Jean-Luc Alessandri
- ...
Nature Genetics
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2020
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Article in a journal
Pby1 is a direct partner of the Dcp2 decapping enzyme
- Clément Charenton
- Claudine Gaudon-Plesse
- Régis Back
- Nathalie Ulryck
- Loreline Cosson
- Bertrand Séraphin
- Marc Graille
Nucleic Acids Research ; Volume: 48
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2017
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Article in a journal
A unique surface on Pat1 C-terminal domain directly interacts with Dcp2 decapping enzyme and Xrn1 5′–3′ mRNA exonuclease in yeast
- Clément Charenton
- Claudine Gaudon-Plesse
- Zaineb Fourati
- Valério Taverniti
- Régis Back
- Olga Kolesnikova
- Bertrand Séraphin
- Marc Graille
Proceedings of the National Academy of Sciences of the United States of America ; Volume: 114 ; Page: E9493-E9501
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2016
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Article in a journal
Structure of the active form of Dcp1–Dcp2 decapping enzyme bound to m7GDP and its Edc3 activator
- Clément Charenton
- Valerio Taverniti
- Claudine Gaudon-Plesse
- Régis Back
- Bertrand Séraphin
- Marc Graille
Nature Structural and Molecular Biology ; Volume: 23 ; Page: 982-986
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2014
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Article in a journal
The C-Terminal Domain from S. cerevisiae Pat1 Displays Two Conserved Regions Involved in Decapping Factor Recruitment
- Zaineb Fourati
- Olga A Kolesnikova
- Régis Back
- Jenny Keller
- Clément Charenton
- Valério Taverniti
- Claudine Gaudon Plesse
- Noureddine Lazar
- Dominique Durand
- Herman van Tilbeurgh
- Bertrand Séraphin
- Marc Graille
PLoS ONE ; Volume: 9 ; Page: e96828
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