Regulation of gene expression in cancer
Team Leader : Irwin DAVIDSON
Department : Functional genomics and cancer
Irwin DAVIDSON
Researcher
irwin@igbmc.fr
Research team(s)
Publications
2023
Article in a journal
Phosphorylation of BRN2 Modulates Its Interaction with the Pax3 Promoter To Control Melanocyte Migration and Proliferation
- Irina Berlin
- Laurence Denat
- Anne-Lise Steunou
- Isabel Puig
- Delphine Champeval
- Sophie Colombo
- Karen Roberts
- Elise Bonvin
- Yveline Bourgeois
- Irwin Davidson
- Veronique Delmas
- Laurence Nieto
- Colin Goding
- Lionel Larue
Molecular and Cellular Biology ; Volume: 32 ; Page: 1237-1247
Article in a journal
Treatment of HCC with claudin-1-specific antibodies suppresses carcinogenic signaling and reprograms the tumor microenvironment
- Natascha Roehlen
- Marion Muller
- Zeina Nehme
- Emilie Crouchet
- Frank Jühling
- Fabio del Zompo
- Sara Cherradi
- François Ht Duong
- Nuno Almeida
- Antonio Saviano
- Mirian Fernández-Vaquero
- Tobias Riedl
- Houssein El Saghire
- Sarah C. Durand
- Clara Ponsolles
- Marine Oudot
- Romain Martin
- Nicolas Brignon
- Emanuele Felli
- Patrick Pessaux
- ...
Journal of Hepatology ; Volume: 78 ; Page: 343-355
Article in a journal
General transcription factor TAF4 antagonizes epigenetic silencing by Polycomb to maintain intestine stem cell functions.
- Susanna Säisä-Borreill
- Guillaume Davidson
- Thomas Kleiber
- Andréa Thevenot
- Elisabeth Martin
- Stanislas Mondot
- Hervé M. Blottiere
- Alexandra Helleux
- Gabrielle Mengus
- Michelina Plateroti
- Isabelle Duluc
- Irwin Davidson
- Jean-Noël Freund
Cell death and differentiation
Article in a journal
Super-enhancer-driven expression of BAHCC1 promotes melanoma cell proliferation and genome stability
- Pietro Berico
- Maguelone Nogaret
- Max Cigrang
- Antonin Lallement
- Fatemeh Vand-Rajabpour
- Amanda Flores-Yanke
- Giovanni Gambi
- Guillaume Davidson
- Leane Seno
- Jolian Obid
- Bujamin H. Vokshi
- Stéphanie Le Gras
- Gabrielle Mengus
- Tao Ye
- Carlos Fernandez Cordero
- Mélanie Dalmasso
- Emmanuel Compe
- Corine Bertolotto
- Eva Hernando
- Irwin Davidson
- ...
Cell Reports ; Volume: 42 ; Page: 113363
Article in a journal
Silencing of genes by promoter hypermethylation shapes tumor microenvironment and resistance to immunotherapy in clear-cell renal cell carcinomas
- Xiaofan Lu
- Yann‐alexandre Vano
- Xiaoping Su
- Alexandra Helleux
- Véronique Lindner
- Roger Mouawad
- Jean-Philippe Spano
- Morgan Roupret
- Eva Comperat
- Virginie Verkarre
- Cheng-Ming Sun
- Mostefa Bennamoun
- Hervé Lang
- Philippe Barthélémy
- Wenxuan Cheng
- Li Xu
- Irwin Davidson
- Fangrong Yan
- Wolf Hervé Fridman
- Catherine Sautès-Fridman
- ...
Cell Reports Medicine ; Volume: 4 ; Page: 101287
2022
Article in a journal
A monoclonal antibody targeting nonjunctional claudin-1 inhibits fibrosis in patient-derived models by modulating cell plasticity
- Natascha Roehlen
- Antonio Saviano
- Houssein El Saghire
- Emilie Crouchet
- Zeina Nehme
- Fabio del Zompo
- Frank Juehling
- Marine Oudot
- Sarah C. Durand
- François Ht Duong
- Sara Cherradi
- Victor Gonzalez Motos
- Nuno Almeida
- Clara Ponsolles
- Laura Heydmann
- Tessa Ostyn
- Antonin Lallement
- Patrick Pessaux
- Emanuele Felli
- Andrea Cavalli
- ...
Science Translational Medicine ; Volume: 14
Article in a journal
The E-cadherin-ESR1-GRPR axis defines a sex-specific metastatic pathway in melanoma
- Jérémy Raymond
- Marie Pouteaux
- Valérie Petit
- Zackie Aktary
- Flavie Luciani
- Maria Wehbe
- Patrick Gizzi
- Claire Bourban
- Igor Martianov
- Irwin Davidson
- Catherine-Laure Tomasetto
- Florence-Mahuteau Betzer
- Béatrice Vergier
- Lionel Larue
- Véronique Delmas
BioRxiv
Article in a journal
The lncRNA LENOX interacts with RAP2C to regulate metabolism and promote resistance to MAPK inhibition in melanoma.
- Giovanni Gambi
- Gabrielle Mengus
- Guillaume Davidson
- Ewout Demesmaeker
- Alessandro Cuomo
- Tiziana Bonaldi
- Vasiliki Katopodi
- Gabriel Malouf
- Eleonora Leucci
- Irwin Davidson
Cancer Research
Article in a journal
Keratinocyte-derived cytokine TSLP promotes growth and metastasis of melanoma by regulating the tumor-associated immune microenvironment
- Wenjin Yao
- Beatriz German
- Dounia Chraa
- Antoine Braud
- Cecile Hugel
- Pierre Meyer
- Guillaume Davidson
- Patrick Laurette
- Gabrielle Mengus
- Eric Flatter
- Pierre Marschall
- Justine Segaud
- Marine Guivarch
- Pierre Hener
- Marie-Christine Birling
- Dan Lipsker
- Irwin Davidson
- Mei Li
JCI Insight
Article in a journal
Immune-Desert Tumor Microenvironment in Thoracic SMARCA4-Deficient Undifferentiated Tumors with Limited Efficacy of Immune Checkpoint Inhibitors
- Justine Gantzer
- Guillaume Davidson
- Bujamin Vokshi
- Noëlle Weingertner
- Antoine Bougoüin
- Marco Moreira
- Véronique Lindner
- Guillaume Lacroix
- Céline Mascaux
- Marie-Pierre Chenard
- F. Bertucci
- Irwin Davidson
- Jean-Emmanuel Kurtz
- Catherine Sautès-Fridman
- Wolf Fridman
- Gabriel Malouf
Oncologist