Chemical biophysics of transcriptional signaling
Team Leader : Annick DEJAEGERE
Department : Integrated structural biology
Natacha ROCHEL-GUIBERTEAU
Researcher
rochel@igbmc.fr
Research team(s)
Research subgroup(s)
Publications
2007
Article in a journal
Silicon analogues of the retinoid agonists TTNPB and 3-methyl-TTNPB, disila-TTNPB and disila-3-methyl-TTNPB: chemistry and biology.
- Matthias W Büttner
- Christian Burschka
- Jürgen O Daiss
- Diana Ivanova
- Natacha Rochel
- Sabrina Kammerer
- Carole Peluso-Iltis
- Audrey Bindler
- Claudine Gaudon
- Pierre Germain
- Dino Moras
- Hinrich Gronemeyer
- Reinhold Tacke
ChemBioChem ; Volume: 8 ; Page: 1688-99
Article in a journal
Crystal structure of the vitamin D nuclear receptor ligand binding domain in complex with a locked side chain analog of calcitriol.
- Natacha Rochel
- Shinji Hourai
- Xenxo Pérez-García
- Antonio Rumbo
- Antonio Mourino
- Dino Moras
Archives of Biochemistry and Biophysics ; Volume: 460 ; Page: 172-6
Article in a journal
Adaptability of the Vitamin D nuclear receptor to the synthetic ligand Gemini: remodelling the LBP with one side chain rotation.
- Fabrice Ciesielski
- Natacha Rochel
- Dino Moras
Journal of Steroid Biochemistry and Molecular Biology ; Volume: 103 ; Page: 235-42
2006
Article in a journal
Co-expression of protein complexes in prokaryotic and eukaryotic hosts: experimental procedures, database tracking and case studies.
- Christophe Romier
- Marouane Ben Jelloul
- Shira Albeck
- Gretel Buchwald
- Didier Busso
- Patrick H N Celie
- Evangelos Christodoulou
- Valeria de Marco
- Suzan van Gerwen
- Puck Knipscheer
- Joyce H Lebbink
- Valerie Notenboom
- Arnaud Poterszman
- Natacha Rochel
- Serge X Cohen
- Tamar Unger
- Joel L Sussman
- Dino Moras
- Titia K Sixma
- Anastassis Perrakis
Acta crystallographica Section D : Structural biology [1993-...] ; Volume: 62 ; Page: 1232-42
Article in a journal
Probing a water channel near the A-ring of receptor-bound 1 alpha,25-dihydroxyvitamin D3 with selected 2 alpha-substituted analogues.
- Shinji Hourai
- Toshie Fujishima
- Atsushi Kittaka
- Yoshitomo Suhara
- Hiroaki Takayama
- Natacha Rochel
- Dino Moras
Journal of Medicinal Chemistry ; Volume: 49 ; Page: 5199-205
Article in a journal
Novel 1alpha,25-dihydroxyvitamin D3 analogues with the side chain at C12.
- Xosé C González-Avión
- Antonio Mouriño
- Natacha Rochel
- Dino Moras
Journal of Medicinal Chemistry ; Volume: 49 ; Page: 1509-16
Article in a journal
Ligand binding domain of vitamin D receptors
- Natacha Rochel
- Dino Moras
Current Topics in Medicinal Chemistry ; Volume: 6 ; Page: 1229-1241
2005
Article in a journal
Superagonistic action of 14-epi-analogs of 1,25-dihydroxyvitamin D explained by vitamin D receptor-coactivator interaction.
- Guy Eelen
- Lieve Verlinden
- Natacha Rochel
- Frank Claessens
- Pierre de Clercq
- Maurits Vandewalle
- Giuseppe D. Tocchini-Valentini
- Dino Moras
- Roger Bouillon
- Annemieke Verstuyf
Molecular Pharmacology ; Volume: 67 ; Page: 1566-73
2004
Article in a journal
Rational design of RAR‐selective ligands revealed by RARβ crystal stucture
- Pierre Germain
- Sabrina Kammerer
- Efrén Pérez
- Carole Peluso-Iltis
- David Tortolani
- F Christopher Zusi
- John Starrett
- Philippe Lapointe
- Jean‐paul Daris
- Anne Marinier
- Angel de Lera
- Natacha Rochel
- Hinrich Gronemeyer
EMBO Reports ; Volume: 5 ; Page: 877-882
Article in a journal
Crystal structures of the vitamin D nuclear receptor liganded with the vitamin D side chain analogues calcipotriol and seocalcitol, receptor agonists of clinical importance. Insights into a structural basis for the switching of calcipotriol to a receptor antagonist by further side chain modification
- Giuseppe Tocchini-Valentini
- Natacha Rochel
- Jean-Marie Wurtz
- Dino Moras
Journal of Medicinal Chemistry ; Volume: 47 ; Page: 1956-1961