Pathophysiology of Down's syndrome and rare dose-effect diseases causing intellectual disabilities (ID) or autism spectrum disorders (ASD) and other comorbidities
Team Leader : Yann HERAULT
Department : Translational medecine and neurogenetics
Yann HERAULT
Researcher
yann.herault@igbmc.fr
Research team(s)
Research subgroup(s)
Publications
2014
Article in a journal
Domains of genome-wide gene expression dysregulation in Down’s syndrome
- Audrey Letourneau
- Federico Santoni
- Ximena Bonilla
- M. Reza Sailani
- David Gonzalez
- Jop Kind
- Claire Chevalier
- Robert Thurman
- Richard Sandstrom
- Youssef Hibaoui
- Marco Garieri
- Konstantin Popadin
- Emilie Falconnet
- Maryline Gagnebin
- Corinne Gehrig
- Anne Vannier
- Michel Guipponi
- Laurent Farinelli
- Daniel Robyr
- Eugenia Migliavacca
- ...
Nature ; Volume: 508 ; Page: 345-350
Article in a journal
Developmental molecular and functional cerebellar alterations induced by PCP4/PEP19 overexpression: implications for Down syndrome.
- François Mouton-Liger
- Ignasi Sahún
- Thibault Collin
- Patricia Lopes Pereira
- Debora Masini
- Sophie Thomas
- Evelyne Paly
- Sabrina Luilier
- Sandra Même
- Quentin Jouhault
- Soumia Bennaï
- Jean-Claude Beloeil
- Jean-Charles Bizot
- Yann Hérault
- Mara Dierssen
- Nicole Créau
Neurobiology of Disease ; Volume: 63 ; Page: 92-106
Article in a journal
In vivo 9.4T MRI and 1H MRS for Evaluation of Brain Structural and Metabolic Changes in the Ts65Dn Mouse Model for Down Syndrome.
- S. Même
- N. Joudiou
- N. Yousfi
- F. Szeremeta
- P. Lopes-Pereira
- J. C. Beloeil
- Y. Herault
- W. Même
World Journal of Neuroscience ; Volume: 04 ; Page: 152-163
Article in a journal
Cognition and Hippocampal Plasticity in the Mouse Is Altered by Monosomy of a Genomic Region Implicated in Down Syndrome
- Ignasi Sahún
- Damien Marechal
- Patricia Lopes Pereira
- Valérie Nalesso
- Agnès Gruart
- José Maria Delgado-García
- Stylianos E. Antonarakis
- Mara Dierssen
- Yann Herault
Genetics ; Volume: 197 ; Page: 899--912
Article in a journal
Skin Progenitor Cells Contribute to Bleomycin-Induced Skin Fibrosis
- Shangxi Liu
- Yann Hérault
- Guillaume Pavlovic
- Andrew Leask
Arthritis & rheumatology ; Volume: 66 ; Page: 707--713
2013
Article in a journal
Epigallocatechin‐3‐gallate, a DYRK1A inhibitor, rescues cognitive deficits in D own syndrome mouse models and in humans
- Rafael de la Torre
- Susana de Sola
- Meritxell Pons
- Arnaud Duchon
- María Martínez de Lagran
- Magí Farré
- Montserrat Fitó
- Bessy Benejam
- Klaus Langohr
- Joan Rodriguez
- Mitona Pujadas
- Jean Charles Bizot
- Aída Cuenca
- Nathalie Janel
- Silvina Catuara
- Maria Isabel Covas
- Henri Blehaut
- Yann Hérault
- Jean Marie Delabar
- Mara Dierssen
Molecular Nutrition and Food Research ; Volume: 58 ; Page: 278-288
Article in a journal
FELASA guidelines for the refinement of methods for genotyping genetically-modified rodents
- Paolo Cinelli
- Eleni Douni
- Yann Hérault
- Alex Maas
- Pirjo Pakarinen
- Matti Poutanen
- Mirentxu Santos Lafuente
- Ferdinando Scavizzi
Laboratory Animals ; Volume: 47 ; Page: 134-145
Article in a journal
The homeodomain factor Gbx1 is required for locomotion and cell specification in the dorsal spinal cord
- Hamid Meziane
- Valérie Fraulob
- Fabrice Riet
- Wojciech Krezel
- Mohammed Selloum
- Michaela Geffarth
- Dario Acampora
- Yann Hérault
- Antonio Simeone
- Michael Brand
- Pascal Dollé
- Muriel Rhinn
PeerJ ; Volume: 1 ; Page: e142
Article in a journal
Surveying the Down syndrome mouse model resource identifies critical regions responsible for chronic otitis media
- Mahmood F. Bhutta
- Michael T. Cheeseman
- Yann Hérault
- Yuejin E. Yu
- Steve D. M. Brown
Mammalian Genome ; Volume: 24 ; Page: 439--445
Article in a journal
DYRK1A overexpression decreases plasma lecithin:cholesterol acyltransferase activity and apolipoprotein A-I levels
- Asma Tlili
- Christophe Noll
- Sandrine Middendorp
- Arnaud Duchon
- Marie Jouan
- Eva Benabou
- Yann Hérault
- Jean-Louis Paul
- Jean-Maurice Delabar
- Nathalie Janel
Molecular Genetics and Metabolism ; Volume: 110 ; Page: 371--377