Pathophysiology of Down's syndrome and rare dose-effect diseases causing intellectual disabilities (ID) or autism spectrum disorders (ASD) and other comorbidities
Team Leader : Yann HERAULT
Department : Translational medecine and neurogenetics
Yann HERAULT
Researcher
yann.herault@igbmc.fr
Research team(s)
Research subgroup(s)
Publications
2015
Article in a journal
Opposite Phenotypes of Muscle Strength and Locomotor Function in Mouse Models of Partial Trisomy and Monosomy 21 for the Proximal Hspa13-App Region
- Véronique Brault
- Arnaud Duchon
- Caroline Romestaing
- Ignasi Sahún
- Stéphanie Pothion
- Mona Karout
- Christelle Borel
- Doulaye Dembele
- Jean-Charles Bizot
- Nadia Messaddeq
- Andrew J. Sharp
- Damien Roussel
- Stylianos E Antonarakis
- Mara Dierssen
- Yann Herault
PLoS Genetics ; Volume: 11 : e1005062. ; Page: 1-27
Article in a journal
La révolution de la génomique fonctionnelle
- Guillaume Pavlovic
- Tania Sorg
- Ali Ayadi
- Marie-Christine Birling
- Isabelle Goncalves
- C Fremont
- B Malissen
- Yann Hérault
Biofutur ; Volume: 34 ; Page: 47-53
Article in a journal
Deletion of the App-Runx1 region in mice models human partial monosomy 21
- Thomas Arbogast
- Matthieu Raveau
- Claire Chevalier
- Valérie Nalesso
- Doulaye Dembele
- Hugues Jacobs
- Olivia Wendling
- Michel J. Roux
- Arnaud Duchon
- Yann Hérault
Disease Models & Mechanisms ; Volume: 8 ; Page: 623-634
Article in a journal
LXR-Mediated ABCA1 Expression and Function Are Modulated by High Glucose and PRMT2
- Maryem A. Hussein
- Elina Shrestha
- Mireille Ouimet
- Tessa J. Barrett
- Sarah Leone
- Kathryn J. Moore
- Yann Herault
- Edward A. Fisher
- Michael J. Garabedian
PLoS ONE ; Volume: 10 ; Page: e0135218
Article in a journal
Conditional depletion of intellectual disability and Parkinsonism candidate gene ATP6AP2 in fly and mouse induces cognitive impairment and neurodegeneration
- Aline Dubos
- Anna Castells-Nobau
- Hamid Meziane
- Merel A.W. Oortveld
- Xander Houbaert
- Giovanni Iacono
- Christelle Martin
- Christophe Mittelhaeuser
- Valérie Lalanne
- Jamie M. Kramer
- Anuradha Bhukel
- Christine Quentin
- Jan Slabbert
- Patrik Verstreken
- Stefan J. Sigrist
- Nadia Messaddeq
- Marie-Christine Birling
- Mohammed Selloum
- Henk G. Stunnenberg
- Yann Humeau
- ...
Human Molecular Genetics ; Volume: 24 ; Page: 6736--6755
Article in a journal
Dosage of the Abcg1-U2af1 Region Modifies Locomotor and Cognitive Deficits Observed in the Tc1 Mouse Model of Down Syndrome
- Damien Marechal
- Patricia Lopes Pereira
- Arnaud Duchon
- Yann Herault
PLoS ONE ; Volume: 10 ; Page: e0115302
Article in a journal
Applying the ARRIVE Guidelines to an In Vivo Database
- Natasha A. Karp
- Terry F. Meehan
- Hugh Morgan
- Jeremy C. Mason
- Andrew Blake
- Natalja Kurbatova
- Damian Smedley
- Julius Jacobsen
- Richard F. Mott
- Vivek Iyer
- Peter Matthews
- David G. Melvin
- Sara Wells
- Ann M. Flenniken
- Hiroshi Masuya
- Shigeharu Wakana
- Jacqueline K. White
- K. C. Kent Lloyd
- Corey L. Reynolds
- Richard Paylor
- ...
PLoS Biology ; Volume: 13 ; Page: e1002151
2014
Article in a journal
Heterozygous deletion of the Williams–Beuren syndrome critical interval in mice recapitulates most features of the human disorder
- Maria Segura-Puimedon
- Ignasi Sahún
- Emilie Velot
- Pierre Dubus
- Cristina Borralleras
- Ana Rodrigues
- Maria Adela Valero
- Olga Valverde
- Nuno Sousa
- Yann Hérault
- Mara Dierssen
- Luis Pérez-Jurado
- Victoria Campuzano
Human Molecular Genetics ; Volume: 23 ; Page: 6481-6494
Article in a journal
Excitation/inhibition balance and learning are modified by Dyrk1a gene dosage
- Benoît Souchet
- Fayçal Guedj
- Ignasi Sahún
- Arnaud Duchon
- Fabrice Daubigney
- Anne Badel
- Yuchio Yanagawa
- Maria-Jose Barallobre
- Mara Dierssen
- Eugene Yu
- Yann Hérault
- Mariona Arbones
- Nathalie Janel
- Nicole Créau
- Jean-Maurice Delabar
Neurobiology of Disease ; Volume: 69 ; Page: 65-75
Article in a journal
Dyrk1A induces pancreatic β cell mass expansion and improves glucose tolerance
- Latif Rachdi
- Dulanjalee Kariyawasam
- Virginie Aïello
- Yann Hérault
- Nathalie Janel
- Jean-Maurice Delabar
- Michel Polak
- Raphaël Scharfmann
Cell Cycle ; Volume: 13 ; Page: 2221-2229